Abstract: A particle therapy system includes a particle accelerator for generating a charged particle beam, a beam delivery device, a beam transport system for transporting the beam from the particle accelerator to the beam delivery device, and a supporting device for supporting a subject. The beam delivery device is rotatable around the target and with respect to the supporting device, so as to be able to deliver the beam to the target according to a plurality of irradiation angles. The system also includes a controller configured to make the beam delivery device rotate at a beam-on speed and meanwhile to irradiate the target with the beam. The controller is configured to make the beam delivery device rotate at at least two different beam-on speeds with respect to the supporting device, a first speed corresponding to a first irradiation angle and a second speed corresponding to a second irradiation angle.

Abstract: The present disclosure relates to a process for purifying and concentrating 68Ga isotope produced by irradiation with an accelerated particle beam of a 68Zn target in solution. The process according to the present disclosure allows for the production of pure and concentrated 68Ga isotope in hydrochloric acid solution. The present disclosure also relates to a disposable cassette for performing the steps of purification and concentration of the process.

Abstract: A magnet for transporting a particle beam in a target magnet field may include a first set of coils and a second set of coils. According to some aspects, the first and second set of coils may be configured to generate a combined desired magnetic field within the bore and may be configured to generate a combined magnetic field weaker than the desired magnetic field outside the bore.

Abstract: An electron accelerator including a resonant cavity, an electron source, an RF system, and at least one magnet unit is provided. The resonant cavity further includes a hollow closed conductor and the electron source is configured to radially inject a beam of electrons into the cavity. The RF system is configured to generate an electric field to accelerate the electrons along radial trajectories. The at least one magnet unit further-includes a deflecting magnet configured to generate a magnetic field that deflects an electron beam emerging out of the resonant cavity along a first radial trajectory and redirects the electron beam into the resonant cavity along a second radial trajectory. The resonant cavity further includes a first half shell, a second half shell, and a central ring element.

Abstract: A capsule for the transfer of a target material in a conveying system between a target irradiation station and a collecting station comprising: a beamline channel for the passage of an energetic beam irradiating the target material, a target holder holding the target material or a substrate backing the target material at a glancing angle with respect to the beamline channel axis, a degrader foil positioned across the beamline channel for degrading an energy of the energetic beam upstream of the target material, a target cooling inlet and a target cooling outlet for passage of a cooling fluid in a target cooling duct in a vicinity of the target holder such that the target material can be cooled during an irradiation, and a degrader foil cooling inlet and a degrader foil cooling outlet for passage of a cooling gas in a vicinity of the degrader foil.

Abstract: A cyclotron for accelerating a beam of charged particles and extracting the beam. The cyclotron includes a vacuum chamber; a target support element sealed and coupled to the vacuum chamber and including a tubular channel leading to a target; first energy specific extraction kit including a first stripper assembly with a stripper located at a first stripping position for stripping charged particles at a first energy and a second energy specific extraction kit for driving modified charged particles of second energy along a second extraction path towards a target holder, wherein the energy specific extraction kit includes: a second stripper assembly with a stripper located at a second stripping position for stripping charged particles at a second energy and an insert for modifying an orientation of the tubular channel to match the second extraction path such that the modified charged particles of second energy intercept the target holder.

Abstract: A cyclotron for accelerating charged particles includes: a first and second superconducting main coils arranged parallel to one another on either side of a median plane; and at least a first and second field bump modules arranged on either side of the median plane, and extending circumferentially over a common azimuthal angle for creating a local magnetic field bump in the main magnetic field. Each of the field bump modules includes at least one superconducting bump coil locally generating a broad magnetic field bump having a bell-shape defined by a first gradient of the z-component in a radial direction, r. Each of the field bump modules further includes at least one superconducting bump shaping unit positioned such as to locally steepen the first gradient produced by the at least one superconducting bump coil, when said at least one superconducting bump shaping unit is activated.

Abstract: An apparatus comprising a wireless communication device for enabling the remote control of a medical apparatus The apparatus includes a remote control enable device comprising a transmitter and one or more switches, actuatable by enable buttons. The buttons allow an operator to close the switch(es), causing the transmitter to send a status signal related to the status (open or closed) of the switch(es), to a receiver configured to communicate said status signal to a control unit. The control unit verifies the signal on a number of criteria. When all required criteria have been met, remote control of the medical apparatus is allowed. In an embodiment the remote control enable device is configured to maintain the power supply to a transmitting chip sufficiently long, upon opening a switch, so that a check can be performed on the correct functioning of the switch after the switch has been opened.

Abstract: The present invention relates to a particle therapy apparatus used for radiation therapy. More particularly, this invention relates to a gantry for delivering particle beams which comprises means to analyse the incoming beam. Means are integrated into the gantry to limit the momentum spread of the beam and/or the emittance of the beam.

Abstract: The present disclosure relates to a magnet pole for an isochronous sector-focused cyclotron having hill and valley sectors alternatively distributed around a central axis, Z, each hill sector having an upper surface bounded by four edges: an upper peripheral edge, an upper central edge, a first and a second upper lateral edges, and a peripheral surface extending from the upper peripheral edge to a lower peripheral line. The upper peripheral edge of at least one hill sector may further include a concave portion with respect to the central axis defining a recess extending at least partially over a portion of the peripheral surface of the corresponding hill sector.

Abstract: An electron accelerator is provided. The electron accelerator comprises a resonant cavity comprising a hollow closed conductor, an electron source configured to inject a beam of electrons, and an RF system. The electron accelerator further comprises a magnet unit, comprising a deflecting magnet. The deflecting magnet is configured to generate a magnetic field in a deflecting chamber in fluid communication with the resonant cavity by a deflecting window. The magnetic field is configured to deflect an electron beam emerging out of the resonant cavity through the deflecting window along a first radial trajectory in the mid-plane (Pm) and to redirect the electron beam into the resonant cavity through the deflecting window towards the central axis along a second radial trajectory. The deflecting magnet is composed of first and second permanent magnets positioned on either side of the mid-plane (Pm).

Abstract: An electron accelerator comprising a resonant cavity, an electron source, an RF system, and at least one magnet unit is provided. The resonant cavity further comprises a hollow closed conductor and the electron source is configured to radially inject a beam of electrons into the cavity. The RF system is configured to generate an electric field to accelerate the electrons along radial trajectories. The at least one magnet unit further comprises a deflecting magnet configured to generate a magnetic field that deflects an electron beam emerging out of the resonant cavity along a first radial trajectory and redirects the electron beam into the resonant cavity along a second radial trajectory. The resonant cavity further comprises a first half shell, a second half shell, and a central ring element.

Abstract: A sensing device for a radiation therapy apparatus, the apparatus comprising an accelerator and a beam-shaping device the beam shaping device being a multi-leaf collimator (MLC) (2) having a plurality of pairs of leaves, and a rotatable gantry, the sensing device comprising: a transmission electronic detector (1) comprising an array of ionization chambers. The ionization chambers are defined by a bias electrode (11a,11b, 34,42) on the one hand and by a planar array of conductive strips (40) or strip assemblies (30) on the other hand. The strips or strip assemblies are associated to the leaf pairs of the MLC. The strips are the collecting electrodes of the ionization chambers.

Abstract: A particle therapy apparatus for irradiating a diseased part of a patient's eye with a charged particle beam comprises a particle accelerator to generate the particle beam, a movable irradiation nozzle adapted to direct the particle beam towards the patient's eye according to different beam directions, and a patient support adapted to receive and hold the patient in a treatment position. The apparatus further comprises a pencil beam scanning subsystem configured to scan the particle beam over the diseased part of the patient's eye, a movable marker arranged in such a way that it is visible by the patient while he is in the treatment position and a controller configured to move said marker to a pre-determined and patient-specific position before starting an irradiation of the eye with the particle beam.

Abstract: The invention relates to a hadron therapy installation that comprises an irradiation unit (1) supported by a rotary support structure, so as to be able to rotate around a target volume (15) centered on the axis of rotation (22), to deliver a treatment beam (17) from different angles on the target volume (15). An imaging device (3, 4) is secured in rotation with the irradiation unit (1) and translatable relative to the irradiation unit (1) between a retracted position at the irradiation unit (1) and a lateral deployed position relative to the target volume (15), such that in its deployed position, the imaging device (3, 4) can rotate around the target volume (15) together with the irradiation unit (1). Such an installation can be used for a cone beam computed tomography method and/or a fluoroscopic imaging method on a patient to be treated in the hadron therapy installation.

Abstract: This disclosure is related to an apparatus and method for commissioning or performing a quality assurance (QA) verification of a radiation therapy (RT) device. The device may comprise: (a) a motorised water phantom; (b) a RT controller configured for obtaining operation parameters of fields, and causing the RT device to emit a beam according to said operations parameters; (c) a QA controller having a memory for storing a measurements plan, the measurements plan including data defining a sequence of fields, and d) a reference radiation detector adapted and positioned for intercepting said radiation beam and for measuring the dose rate of said radiation beam. The reference radiation detector may be substantially transparent to the radiation beam. The QA controller may include an acquisition interface for acquiring and storing the dose rate from the reference radiation detector.

Abstract: A phantom and method for quality assurance of a particle therapy apparatus used in the intensity modulated particle therapy (IMPT) mode is provided. The phantom comprises a frame structure having a first face and a second face that is parallel to the first face. The phantom further comprises one or more wedges, and a first and second block of material each having a first block face and a second block face parallel thereto. In addition, the phantom further includes an absolute dosimeter arranged at the first block face. A plurality of beads of high density material is located in the first or second block, and a 2D detector is arranged at the second face of the frame structure.

Abstract: In accordance with the embodiments of the present disclosure, a rack comprising a frame having first vertical posts on a first side and second vertical posts on a second side, between which a plurality of RF amplifier modules are mounted, is provided. The RF power outputs of the RF amplifier modules are connected to inputs of an RF power combiner to deliver a combined RF power output. The RF power combiner is arranged at least partially in at least one of a first volume between the first vertical posts of the frame or a second volume between the second vertical posts of the frame, thereby reducing a footprint of the rack.

Abstract: The embodiments of the present disclosure relate to a method and system for controlling the extraction of ion beam pulses produced by a synchrocyclotron. The synchrocyclotron comprises electrodes configured to be placed in a magnetic field. An alternating voltage is applied between the electrodes, and the frequency of the alternating voltage is modulated in a cyclic manner. In other embodiments, the method further comprises the steps of starting an acceleration cycle of the synchrocyclotron, generating a reference signal when the modulated frequency reaches a predefined value, communicating the time, at which the reference signal is generated, to the beam control elements, assessing one or more status parameters of the one or more beam control elements, and cancelling or proceeding with the extraction of the beam pulse depending on the results of the assessment.

Abstract: The present disclosure relates to a magnet pole for an isochronous sector-focused cyclotron having hill and valley sectors alternatively distributed around a central axis, Z, each hill sector having an upper surface bounded by four edges: an upper peripheral edge, an upper central edge, a first and a second upper lateral edges. The upper surface of at least one hill sector may further include: a recess extending over a length between a proximal end and a distal end along a longitudinal axis intersecting the upper peripheral edge and the upper central edge. The recess may be separate from the first and second upper lateral edges over at least 80% of its length, and a pole insert having a geometry fitting in the recess may be positioned in, and reversibly coupled to the recess.