Abstract: A balloon catheter for use with a guidewire is disclosed. The catheter has a body with a balloon located thereon, preferably at the distal end. A lumen within the catheter body communicates with the interior of the balloon which can be inflated by known methods with saline solution. A series of sleeve members of predetermined lengths and sizes are coupled to and positioned along the length of the catheter body. One or more of the sleeve members can span the length of the balloon. Each sleeve member has a passageway and both an exit and entry port so that the guidewire can pass therethrough. Instead of a balloon, the catheter can include a device member that forms a chamber which can store medicine until discharged at the desired site within the blood vessel. Apertures or pores on the catheter body allow for the perfusion of blood or the delivery of medicine to the site of the blood vessel. A method of operation is also disclosed.

Abstract: The invention relates to a stent preform for implantation in a body lumen. The stent preform includes an elongated metal core having first and second core ends, a contact surface, and a solid cross-section, and a hollow outer sheath made of a biocompatible polymer and having first and second sheath ends, caps disposed on the sheath ends, and an interior surface. The outer sheath surrounds and contacts the contact surface of the core to prevent the core from directly contacting the body lumen. In another embodiment, the biocompatible polymer of the outer sheath is formed of a heat-shrinkable polymer material, and the elongated core is formed of a shape-memory alloy. In another embodiment, the outer sheath is formed from a polymer tape.

Abstract: The invention relates to a stent preform for implantation in a body lumen. The stent preform includes an elongated metal core having first and second core ends, a contact surface, and a solid cross-section, and a hollow outer sheath made of a biocompatible polymer and having first and second sheath ends, caps disposed on the sheath ends, and an interior surface. The outer sheath surrounds and contacts the contact surface of the core to prevent the core from directly contacting the body lumen. In another embodiment, the biocompatible polymer of the outer sheath is formed of a heat-shrinkable polymer material, and the elongated core is formed of a shape-memory alloy. In another embodiment, the outer sheath is formed from a polymer tape.

Abstract: A balloon catheter for use with a guidewire is disclosed. The catheter has a body with a balloon located thereon, preferably at the distal end. A lumen within the catheter body communicates with the interior of the balloon which can be inflated by known methods with saline solution. A series of sleeve members of predetermined lengths and sizes are coupled to and positioned along the length of the catheter body. One or more of the sleeve members can span the length of the balloon. Each sleeve member has a passageway and both an exit and entry port so that the guidewire can pass therethrough. Instead of a balloon, the catheter can include a device member that forms a chamber which can store medicine until discharged at the desired site within the blood vessel. Apertures or pores on the catheter body allow for the perfusion of blood or the delivery of medicine to the site of the blood vessel. A method of operation is also disclosed.

Abstract: A stent is disclosed in several embodiments including the use of a material known as NITINOL forming the ends of the stent as well as support structure connecting the ends. A fabric is interconnected with the NITINOL structure to form the stent. The NITINOL material ends have slits parallel with the direction of elongation of the stent allowing radial expansion of the ends. The pieces interconnecting the ends have a serpentine shape allowing longitudinal expansion of the stent. The NITINOL material structure may be located within the fabric portion or outside the fabric portion. The connecting pieces may be separate structures attached to the fabric. Alternatively, the end pieces may be separate structures attached to the fabric without the connecting pieces.

Abstract: A balloon catheter for use with a guidewire is disclosed. The catheter has a body with a balloon located thereon, preferably at the distal end. A lumen within the catheter body communicates with the interior of the balloon which can be inflated by known methods with saline solution. A series of sleeve members of predetermined lengths and sizes are coupled to and positioned along the length of the catheter body. One or more of the sleeve members can span the length of the balloon. Each sleeve member has a passageway and both an exit and entry port so that the guidewire can pass therethrough. Instead of a balloon, the catheter can include a device member that forms a chamber which can store medicine until discharged at the desired site within the blood vessel. Apertures or pores on the catheter body allow for the perfusion of blood or the delivery of medicine to the site of the blood vessel. A method of operation is also disclosed.

Abstract: A stent is disclosed in several embodiments including the use of a material known as NITINOL forming the ends of the stent as well as support structure connecting the ends. A fabric is interconnected with the NITINOL structure to form the stent. The NITINOL material ends have slits parallel with the direction of elongation of the stent allowing radial expansion of the ends. The pieces interconnecting the ends have a serpentine shape allowing longitudinal expansion of the stent. The NITINOL material structure may be located within the fabric portion or outside the fabric portion. The connecting pieces may be separate structures attached to the fabric. Alternatively, the end pieces may be separate structures attached to the fabric without the connecting pieces.

Abstract: A stent is made generally tubular and is initially formed in a collapsed configuration. A fabric cover is provided for the inner stent and is attached outside the stent at one or more desired locations. The fabric cover is larger in diameter than the diameter of the collapsed stent, however, when the stent is expanded through activation of the balloon catheter therewithin, the stent expands to closely conform to the interior walls of the fabric cover. The securement of the fabric cover or intermediate stent layer about the inner stent is accomplished through the use of a wire spiraling externally about the outer surface of the fabric cover to secure the fabric cover or intermediate stent layer about the inner stent. When the stent sandwich is expanded, the configuration of this spiraling wire permits it to expand as well and lie against the inner walls of the blood vessel at the desired location. The stent has spaced ends, each of which may be coated or otherwise provided with a radio-opaque material.

Abstract: A stent is made of a fabric interlaced in a knitting machine. The knitting machine receives a plurality of fabric strands and at least one wire strand from spools and knits them into a tubular fabric stent having at least one reinforcing wire interwoven in the fabric. If desired, the spool carrying the wire may rotate more slowly than the yarn spools so that the wire is braided about the yarn locking the yarn together. The wire may be made of materials such as Stainless Steel, Tungsten, Titanium, NITINOL a nickel-titanium alloy, Gold or Silver.

Abstract: A star-shaped stent and replacement valve or replacement graft for use in repairing damaged vascular organs: Two to eight star-shaped members are interconnected into a "chain". Once this "chain" has been created through interconnection of the star-shaped members, a central opening through all of the interconnected star-shaped members receives a graft made of any suitable flexible and bio-compatible material. A catheter delivery system is used to deliver the stent with the graft to the desired site. The star-shaped stents are made by using a laser to cut out a plurality of flat star-shaped members with a plurality of outwardly and inwardly directed points. The outwardly directed points are bent so that they face away from a plane defined by the inwardly directed points and then a series of such stents are fastened together in a chain.

Abstract: The present invention preferably includes a balloon catheter for use with a guidewire. The catheter has a body with a balloon located thereon, preferably at the distal end. A lumen within the catheter body communicates with the interior of the balloon which can be inflated by known methods with saline solution. A series of sleeve members of predetermined lengths and sizes are coupled to and positioned along the length of the catheter body. One or more of the sleeve members can span the length of the balloon. Each sleeve member has a passageway and both an exit and entry port so that the guidewire can pass therethrough. Instead of a balloon, the catheter can include a device member that forms a chamber which can store medicine until discharged at the desired site within the blood vessel. Apertures or pores on the catheter body allow for the perfusion of blood or the delivery of medicine to the site of the blood vessel. A method of operation is also disclosed.

Abstract: A stent is made generally tubular and is initially formed in a collapsed configuration. A fabric cover is provided for the inner stent and is attached outside the stent at one or more desired locations. The fabric cover is much larger in diameter than the diameter of the collapsed stent, however, when the stent is expanded through activation of the balloon catheter therewithin, the stent expands to closely conform to the interior walls of the fabric cover. The attachment of the fabric cover and the stent may be accomplished in several ways. In one embodiment, the fabric cover may be attached outside the inner stent at one linear location parallel to the axis of elongation of the stent. In an alternative embodiment, the fabric cover may be attached concentrically about the inner stent and secured in that configuration by a series of sutures. In a further modification, the fabric cover may be attached around the inner stent non-concentrically through the use of suitable sutures.

Abstract: A stent has a generally cylindrical shape having a series of slots or other surface discontinuities facilitating adherence to the inner walls of a blood vessel. In one embodiment, one end of the stent has a terminus that is tapered at a non-orthogonal angle with respect to the axis of elongation of the stent. In other embodiments, both ends are angled non-orthogonally with respect to the longitudinal axis of the stent. The particular angle that each end surface of the stent makes with the longitudinal axis of the stent may be varied, in each case, to accommodate to bifurcated blood vessels of varying sizes, shapes and configurations. Use of stents in accordance with the teachings of the present invention precludes wall portions of a stent from protruding into a passage of a blood vessel in a manner that would cause restricted flow through the blood vessel. The method of making the stent in accordance with the teachings of the present invention is also disclosed.

Abstract: A metallic stent is coated with a synthetic or biological active or inactive agent that only adheres to the metallic surface of the stent and does not cover slots formed in the stent. In the method, a metallic stent is manufactured in a known manner and is then cleaned to remove surface contaminants and carbon deposits formed from cutting operations and electro-polishing procedures. The stent is then dried in a chamber in which nitrogen gas is purged and then placed in a bath containing a suitable surfactant, such as a long chain alkyl quaternary salt, that removes any residual carbon on the surface of the stent. The stent is then placed in a container filled with the coating agent and the container is placed in an ultrasonic bath. When the bath is activated, the stent swirls in the agent, which agent coats the stent but does not cover the slots of the stent. The stent is removed from the container and dried in a controlled atmosphere.

Abstract: Embodiments of multiple interconnected stents each include a stent having a plurality of rows of slots with spaces between the slots being staggered in adjacent rows. In each embodiment, a plurality of stents are interconnected together with a connector. In one embodiment, the connector consists of a single flexible bar. In a second embodiment, the connector consists of a plurality of U-shaped members fused together. In a third embodiment, the connector consists of a plurality of slots orthogonal to the stent slots. In a fourth embodiment, a multiplicity of stents are interconnected together by flexible bars that are vertically staggered with respect to one another. In a fifth embodiment, adjacent stents are interconnected by flexible connectors resembling the letter "H". In a sixth embodiment, adjacent stents are interconnected by a plurality of vertically spaced horizontal bars.

Abstract: A tubular member is formed from a flat sheet having opposed longitudinal edges. Rows of parallel longitudinal slots are cut in the flat sheet and at least three holes are cut along the opposed longitudinal edges. The holes are aligned with the holes on the opposed edge and sutured together to form the tubular member. The tubular member is compressed over a balloon catheter and thereafter permanently positioned within a desired portion of a blood vessel.