Patents Assigned to IPSEN BIOINNOVATION LIMTIED
  • Therapeutic fusion proteins
    Patent number: 10704038
    Abstract: The present invention relates to the construction of a new class of Targeted Secretion Inhibitors (TSIs), which comprise a non-cytotoxic protease, translocation peptide and a targeting moiety peptide, wherein the targeting moiety peptide has a free N-terminal domain and a free C-terminal domain; to a single-chain fusion protein precursor thereof, and to a method of activating said single-chain fusion protein precursor.
    Type: Grant
    Filed: August 20, 2018
    Date of Patent: July 7, 2020
    Assignee: IPSEN BIOINNOVATION LIMTIED
    Inventors: John Chaddock, Elaine Harper