Abstract: The present invention relates to the use of a gonadotropin-releasing hormone (including GnRH I, a GnRH I analogue, GnRH II, or a GnRH II analogue) as adjuvant immunotherapeutic.
Type:
Grant
Filed:
February 22, 2018
Date of Patent:
June 13, 2023
Assignee:
ISR IMMUNE SYSTEM REGULATION HOLDING AB (PUBL)
Abstract: The present invention provides immune stimulating peptides (immunorhelins) capable of activating GnRH receptors when administered to animal or human patients or cells. These immunorhelins have utility in treating intracellular bacterial, fungal, and protozoal infections.
Type:
Grant
Filed:
January 19, 2018
Date of Patent:
January 31, 2023
Assignee:
ISR IMMUNE SYSTEM REGULATION HOLDING AB (publ)
Inventors:
Ola Winqvist, Emma Lindh, Robert Wallin, Matt Gregory, Steven Moss
Abstract: The present invention provides a method of treating intracellular infections, in particular intracellular bacterial, fungal, and protozoal infections.
Type:
Grant
Filed:
January 19, 2018
Date of Patent:
April 19, 2022
Assignee:
ISR IMMUNE SYSTEM REGULATION HOLDING AB (PUBL)
Inventors:
Ola Winqvist, Emma Lindh, Robert Wallin, Matt Gregory, Steven Moss
Abstract: The present invention provides immune stimulating macrolides of formula (I), wherein the substituents are as defined in claim 1. The macrolides have utility in treating intracellular bacterial, fungal, and protozoal infections.
Type:
Grant
Filed:
February 22, 2018
Date of Patent:
July 13, 2021
Assignee:
ISR IMMUNE SYSTEM REGULATION HOLDING AB (PUBL)
Inventors:
Ola Winqvist, Emma Lindh, Robert Wallin, Matt Gregory, Steven Moss
Abstract: The present invention provides immune stimulating macrolides of formula (I), wherein the substituents are as defined in the claims. The macrolides have utility in treating viral diseases and cancer.
Type:
Grant
Filed:
February 22, 2018
Date of Patent:
July 13, 2021
Assignee:
ISR IMMUNE SYSTEM REGULATION HOLDING AB (PUBL)
Inventors:
Ola Winqvist, Emma Lindh, Robert Wallin, Matt Gregory, Steven Moss
Abstract: The present invention provides immune stimulating macrolide of formula (I). The macrolide has utility in treating intracellular bacterial, fungal, and protozoal infections.
Type:
Grant
Filed:
February 22, 2018
Date of Patent:
July 13, 2021
Assignee:
ISR IMMUNE SYSTEM REGULATION HOLDING AB (PUBL)
Inventors:
Ola Winqvist, Emma Lindh, Robert Wallin, Matt Gregory, Steven Moss