Patents Assigned to iviGene Corporation
  • In situ induced antigen technology (isiat) for identification of polynucleotides expressed during infection or colonization
    Publication number: 20060099579
    Abstract: The invention provides compositions and methods for identifying polynucleotides and polypeptides expressed by a microbe during infection or colonization. The invention also provides compositions and methods for identifying polynucleotides and polypeptides expressed by a host organism in response to a disease state. The invention also provides methods and compositions for the diagnosis, treatment, prevention, and amelioration of diseases and infections caused by microbes.
    Type: Application
    Filed: February 24, 2003
    Publication date: May 11, 2006
    Applicant: iviGene Corporation
    Inventor: Jeffrey Hillman
  • Identification of microbial polynucleotides expressed during infection of a host
    Patent number: 7033748
    Abstract: The invention provides methods useful for identifying polynucleotides expressed in vivo by a microbe during infection of a host. Antibodies against antigens that are expressed by the microbe in vivo and in vitro are adsorbed with cells or cellular extracts of the microbe that have been grown in vitro. Unadsorbed antibodies are isolated and are probed against a phage display library of the microbe's DNA or RNA. A polynucleotide of the microbe that is expressed in vivo is isolated and identified.
    Type: Grant
    Filed: March 6, 2002
    Date of Patent: April 25, 2006
    Assignee: iviGene Corporation
    Inventor: Jeffrey Daniel Hillman
  • Identification of microbial polynucleotides expressed during infection of a host
    Publication number: 20020197625
    Abstract: The invention provides methods useful for identifying polynucleotides expressed in vivo by a microbe during infection of a host. Antibodies against antigens that are expressed by the microbe in vivo and in vitro are adsorbed with cells or cellular extracts of the microbe that have been grown in vitro. Unadsorbed antibodies are isolated and are probed against a phage display library of the microbe's DNA or RNA. A polynucleotide of the microbe that is expressed in vivo is isolated and identified.
    Type: Application
    Filed: March 6, 2002
    Publication date: December 26, 2002
    Applicant: iviGene Corporation
    Inventor: Jeffrey Daniel Hillman