Abstract: A formulation for use to treat a person who snores when he or she sleeps, the said formulation comprising an effective amount of yohimbine (3.alpha.-15.alpha.-20.beta.-17.alpha.-hydroxy yohimbine-16.alpha.carboxylic acid methyl ester) and pharmaceutically tolerable forms thereof (for example, salts, esters and the like), in a pharmaceutically acceptable carrier.