Abstract: The present invention relates to a novel use of a panduratin derivative or a Boesenbergia pandurata extract. More specifically, the invention relates to a composition for preventing and treating/relieving a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes, containing a panduratin derivative represented by Chemical Formula 1, 2 or 3 or a Boesenbergia pandurata extract as an active ingredient, a method for treating a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes, by administering an effective amount of the panduratin derivative or the Boesenbergia pandurata extract to a subject in need thereof, and a use of the panduratin derivative or the Boesenbergia pandurata extract to prepare a reagent for preventing and treating/relieving a metabolic disease selected from a group consisting of obesity, hyperlipidemia, hypercholesterolemia and diabetes.
Abstract: The present invention relates to the use of lignan compounds for treating or preventing an inflammatory disease. More particularly, it relates to a method for preventing or treating an inflammatory disease, comprising administering to a subject in need thereof an effective amount of macelignan represented by Chemical Formula I or a pharmaceutically acceptable salt thereof. The lignan compound has the effect of inhibiting inflammatory reactions by inhibiting the production or expression of inflammation mediators NO, iNOS, PGE2, COX-2 and TNF-? and by treating or preventing inflammatory disease in vivo. Accordingly, the lignan compound or a Myristica fragrans extract will be highly useful for the treatment or prevention of an inflammatory disease.
Type:
Application
Filed:
April 23, 2010
Publication date:
November 11, 2010
Applicants:
NEWTREE INDUSTRY CO., LTD., Jae-Kwan
Inventors:
Jae-Kwan Hwang, Do-Un Kim, Jae-Youn Chung, Hee-Chul Chung, Kyu-Lee Han
Abstract: Disclosed is a seismic load transmitting system based on impact mechanism for a multi-span continuous bridge, comprising impact assemblies connected to a superstructure of the bridge for colliding with movable support piers according to a longitudinal displacement of the superstructure of the bridge caused by a seismic load and transmitting the seismic load from the superstructure of the bridge to the movable support piers; and impact receiving assemblies installed in the movable support piers for receiving an impact force generated when the movable support piers become collided with the impact assemblies and transmitting the seismic load transferred from the superstructure of the bridge through the impact assemblies to the movable support piers, wherein the seismic load generated in the superstructure of the bridge is transmitted not only to the fixed support piers but also to the moving support piers due to the collision between the impact assemblies and the impact receiving assemblies; and wherein the cont