Patents Assigned to Japan as Represented by the Director-General of National Inst. of Infectious Diseases
  • WEST NILE VIRUS VACCINE, AND METHOD FOR PRODUCTION THEREOF
    Publication number: 20140065180
    Abstract: The invention provides virus-like particles (VLP) highly secreting or producing signal peptide obtained by altering a signal sequence derived from West Nile virus (WNV), the signal peptide, a WNV VLP secretion expression vector containing a nucleic acid encoding prM protein and E protein, a WNP VLP highly secreting or producing animal cell line harboring the vector, a WNV vaccine containing WNV VLP obtained by the cell line as an active ingredient, and a WNV DNA vaccine containing the VLP secretion expression vector as an active ingredient.
    Type: Application
    Filed: November 4, 2013
    Publication date: March 6, 2014
    Applicants: The Research Foundation for Microbial Diseases of Osaka University, Japan as Represented by the Director-General of National Inst. of Infectious Diseases
    Inventors: Asato KOJIMA, Hidehiro TAKAHASHI, Toyokazu ISHIKAWA