Abstract: An electrode material for an electrochemical device comprising a composite of a particulate conductive material and a metal oxide is prepared by mixing and dispersing the particulate conductive material with a colloidal solution of an oxide of an element in a range of from Group 3 to Group 12 in the fourth, fifth and sixth periods of the Periodic Table and heating the mixture. This composite has a high capacity even at a high current density and good filling properties, and is useful as an electrode material for an electrochemical device such as a lithium secondary battery or an electrochemical capacitor. When the electrode material comprising this composite is used, an electrode can be produced without any binder, and the electrochemical device having good output characteristics can be constructed.
Type:
Grant
Filed:
September 6, 2001
Date of Patent:
December 1, 2009
Assignees:
Hitachi Maxell, Ltd., Japan as Represented by the President of the University of Tokyo
Abstract: p53-dependent Damage-Inducible Nuclear Protein 1 (p53DINP1 protein) is a p53-induced nuclear protein that induces p53-dependent apoptosis by regulating p53 function through Ser 46 phosphorylation. A DNA encoding p53DINP1 can be applied as anticancer agents for destroying neoplasms such as tumors, and as therapeutic or preventive agents for diseases associated with p53-mediated apoptosis abnormalities. It is also possible to apply the above protein and DNA in methods of screening for candidate compounds for regulating p53-mediated apoptosis.
Type:
Application
Filed:
April 16, 2008
Publication date:
September 11, 2008
Applicants:
Japan as Represented be the President of the University of Tokyo, Oncotherapy science, Inc.
Abstract: p53-dependent Damage-Inducible Nuclear Protein 1 (p53DINP1 protein) is a p53-induced nuclear protein that induces p53-dependent apoptosis by regulating p53 function through Ser 46 phosphorylation. A DNA encoding p53DINP1 can be applied as anticancer agents for destroying neoplasms such as tumors, and as therapeutic or preventive agents for diseases associated with p53-mediated apoptosis abnormalities. It is also possible to apply the above protein and DNA in methods of screening for candidate compounds for regulating p53-mediated apoptosis.
Type:
Grant
Filed:
July 18, 2002
Date of Patent:
May 13, 2008
Assignees:
Japan as Represented by the President of the University of Tokyo, Oncotherapy Science, Inc.
Abstract: A core layer contains photonic crystals formed by ferroelectric members made of a ferroelectric substance and periodically disposed along a one-dimensional direction or two-dimensional directions. Electrodes apply an electric field to the core layer. An optical function device is provided which can be made compact and can set a wavelength at high speed.
Type:
Grant
Filed:
March 19, 2004
Date of Patent:
April 25, 2006
Assignees:
Fujitsu Limited, Japan as represented by the President of The University of Tokyo
Abstract: The present invention relates to the use of cytoxicity based on the effector function of anti-FAM3D antibodies. Specifically, the present invention provides methods and pharmaceutical compositions that comprise an anti-FAM3D antibody as an active ingredient for damaging FAM3D-expressing cells using antibody effector function. Since FAM3D is strongly expressed in lung cancer cells, the present invention is useful in lung cancer therapies.
Type:
Application
Filed:
March 24, 2004
Publication date:
September 29, 2005
Applicants:
Oncotherapy Science, Inc., Japan as Represented by the President of the University of Tokyo
Abstract: This invention demonstrates that the PEG10 protein suppresses apoptosis and promotes cancer cell growth. Furthermore, PEG10 protein was found to be degraded through interaction with SIAH1 protein. This invention provides methods of regulating cell growth and cell death using the PEG10 protein. Furthermore, the present invention provides methods of screening for novel anticancer agents which use the PEG10 protein. The screening of this invention enables development of pharmaceutical agents that induce apoptosis and suppress cell growth by specifically targeting cancer cells. In particular, since the PEG10 protein is specifically expressed in hepatoma cells, it is an ideal target molecule for diagnosis and treatment of hepatoma.
Type:
Application
Filed:
August 21, 2002
Publication date:
March 31, 2005
Applicants:
JAPAN AS REPRESENTED BY THE PRESIDENT OF THE UNIVERSITY OF TOKYO, ONCOTHERAPY SCIENCE, INC.
Abstract: A core layer contains photonic crystals formed by ferroelectric members made of a ferroelectric substance and periodically disposed along a one-dimensional direction or two-dimensional directions. Electrodes apply an electric field to the core layer. An optical function device is provided which can be made compact and can set a wavelength at high speed.
Type:
Application
Filed:
March 19, 2004
Publication date:
September 23, 2004
Applicants:
FUJITSU LIMITED, JAPAN AS REPRESENTED BY THE PRESIDENT OF THE UNIVERSITY OF TOKYO
Abstract: A ligand expressed by a general formula (1) in claim 1, wherein R1, R2 and R3 denote substituting groups on aromatic rings, X is P or As, and n is 1 to 3.
Type:
Grant
Filed:
July 30, 2002
Date of Patent:
January 13, 2004
Assignee:
Japan as represented by President of the University of
Tokyo