Patents Assigned to JCRT Radiation Oncology Support Services, Inc.
  • Drug complex for treatment of metastatic prostate cancer
    Publication number: 20050233948
    Abstract: A drug complex for delivery of a drug or other agent to a target cell, comprising a targeting carrier molecule which is selectively distributed to a specific cell type or tissue containing the specific cell type; a linker which is acted upon by a molecule which is present at an effective concentration in the environs of the specific cell type; and a drug or an agent to be delivered to the specific cell type. In particular, a drug complex for delivering a cytotoxic drug to prostate cancer cells, comprising a targeting carrier molecule which is selectively delivered to prostate tissue, bone or both; a peptide which is a substrate for prostate specific antigen; and a cytotoxic drug which is toxic to androgen independent prostate cancer cells.
    Type: Application
    Filed: April 8, 2005
    Publication date: October 20, 2005
    Applicants: Beth Israel Deaconess Medical Center, Northeastern University, JCRT Radiation Oncology Support Services, Inc.
    Inventors: Anthony D'Amico, Glenn Bubley, David Jebaratnam, James Weinberg
  • Drug complex for treatment of metastatic prostate cancer
    Patent number: 6368598
    Abstract: A drug complex for delivery of a drug or other agent to a target cell, comprising a targeting carrier molecule which is selectively distributed to a specific cell type or tissue containing the specific cell type; a linker which is acted upon by a molecule which is present at an effective concentration in the environs of the specific cell type; and a drug or an agent to be delivered to the specific cell type. In particular, a drug complex for delivering a cytotoxic drug to prostate cancer cells, comprising a targeting carrier molecule which is selectively delivered to prostate tissue, bone or both; a peptide which is a substrate for prostate specific antigen; and a cytotoxic drug which is toxic to androgen independent prostate cancer cells.
    Type: Grant
    Filed: July 6, 1998
    Date of Patent: April 9, 2002
    Assignee: JCRT Radiation Oncology Support Services, Inc.
    Inventors: Anthony V. D'Amico, Glenn J. Bubley, David J. Jebaratnam, James S. Weinberg