Abstract: Disclosed are a full-automatic storage shelf assembly production line and an operation method thereof. The production line includes a logistics channel, a stand column-based feeding area, a supporting beam-based feeding area, an in-line logistics system, a shelf assembly area, a finished product area, and a control system. The stand column-based feeding area, the supporting beam-based feeding area, the shelf assembly area, and the finished product area are connected in series by means of the in-line logistics system to form an integrated production line.