Abstract: The present invention relates to compositions comprising one or more extracts and/or compounds having retinol-like activity and properties and methods of using the compositions to treat the eye.

Abstract: An ocular surgical apparatus is provided, including a processor configured to receive ocular surgical data and a graphical user interface configured to display the ocular surgical data to a user. The processor configured to filter the ocular surgical data and the graphical user interface configured to display filtered ocular surgical data. The processor is configured to receive a number of ocular surgical data samples, discard selected ocular surgical data samples thereby yielding a number of emphasized samples, and perform an operation on the number of emphasized samples to produce filtered ocular surgical data.

Abstract: Disclosed are co-polymers which are produced from reactive monomer mixtures and which have both high refractive index and a high Abbe number. These materials are well suited for use as implantable ophthalmic devices and have a refractive index which may be edited through application of energy. When used for an intraocular lens, the high refractive index allows for a thin lens which compresses to allow a small incision size.

Abstract: A packaged elongate sanitary protection product includes a folded sanitary protection product enveloped in a substantially circular package and having first and second arcuate end portions comprising first and second ends, respectively, separated by a central portion. The topsheet and backsheet are joined in a flange surrounding the absorbent structure, and the absorbent structure comprises at least three intersecting, substantially circular sections aligned along a longitudinal axis. A first circular section is associated with the first arcuate end portion, and a second section is associated with the second arcuate end portion, and a central portion is associated with at least one intervening substantially circular portion. The intersections define folding axes perpendicular to the longitudinal axis and enlarged flange sections of the topsheet and backsheet. The product is folded at the fold lines and the enlarged flange sections are folded inwardly to give the product a generally circular form.

Abstract: A method of assessing and/or quantifying remineralization in a tooth model by exposing a tooth model to calcium and a calcium-binding fluorophore either sequentially or simultaneously under conditions sufficient to produce a remineralized/demineralized tooth model; exposing the remineralized/demineralized tooth model to a non-calcium binding fluorophore to produce an enhanced tooth model; and assessing and/or quantifying remineralization, demineralization, or both on the enhanced tooth model by determining the location and extent of calcium binding fluorophore and non-calcium binding fluorophore on the enhanced test tooth sample.

Abstract: The present disclosure relates to ophthalmic devices such as ophthalmic lenses. An ophthalmic device may comprise an ophthalmic lens for at least one of slowing, retarding or preventing myopia progression. The ophthalmic lens may comprise a center zone with a negative power for myopic vision correction; and at least one treatment zone surrounding the center zone, the at least one treatment zone having a power profile comprising an ADD power, the at least one treatment zone having a surface shape comprising a portion of a generally toroidal shape, wherein the at least one treatment zone is arranged as to form a continuous surface with the center zone.

Abstract: A method for making a hydrogel, photochromic contact lens including supplying a first lens composition comprising a contact lens monomer and a photochromic material to a front contact lens mold and supplying a second lens composition to said contact lens mold wherein the viscosity of said first composition is at least about 1000 cp greater than the viscosity of said second contact lens composition, and the makeup of said second composition matches the of said first composition to reduce strain between said compositions of the resulting lens.

Abstract: The disclosed apparatus, system and method may include at least a phacoemulsification surgical console having a customizable non-linear custom phacoemulsification mode. The apparatus, system and method may include an ultrasonic delivery tip; a foot pedal; and non-transitory computing code resident on a computing memory associated with a computing processor which, when executed by the processor, causes to be executed the steps of: receiving a percentage actuation of the foot pedal; calculating, including from a non-linear algorithm, a percentage actuation for the ultrasonic delivery tip corresponded to the received percentage foot pedal actuation; and dictating the calculated percentage actuation for the ultrasonic delivery tip actuation to the ultrasonic delivery tip.

Abstract: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator; (c) contacting the crosslinked substrate network with a grafting composition containing one or more ethylenically unsaturated compounds, wherein the contacting is conducted under conditions such that the grafting composition penetrates into the crosslinked substrate network; and (d) activating the covalently bound activatable free radical initiator at one or more selective regions of the crossli

Abstract: An improved immediate release solid dosage form of naproxen with a certain particle size distribution for the intragranular portion, and a certain particle size distribution for the carbonate portion that allows naproxen to remain in solution and achieves fast dissolution and fast absorption of naproxen. The invention provides a naproxen dosage form that when administered to a human in a fasted state provides an average blood plasma naproxen concentration of at least 15-20 ?g/ml in 10 minutes or less. The invention also provides a naproxen dosage form that when administered to a human in a fed state provides an average blood plasma naproxen concentration of at least 15-20 ?g/ml in 50 minutes or less.

Abstract: Provided are articles such as medical devices which comprise at least one water soluble, crosslinked copolymer. The primary polymer chains of the copolymer are hydrophilic and independently have a degree of polymerization in the range of about 10 to about 10,000. The water soluble, crosslinked copolymers of the present invention are free from terminal substrate associating segments. The copolymers may be incorporated into a formulation from which the article is made or may be contacted with the article post-formation.

Abstract: A contact lens incorporating one or more surface modified zones on the anterior surface of the lens may be utilized to generate a friction driven rotational force when the upper and/or lower eyelids pass over the one or more regions during blinking. A small difference in the coefficient of friction between the modified and unmodified regions of the lens may result in an equivalent rotational force to that of a thickness gradient lens. This small difference in the coefficient of friction produces a means to orient and stabilize the contact lens on eye.

Abstract: A pneumatic cross-connect proportional valve provides the capability to calibrate pressure and vacuum sensors in a surgical cassette associated with a surgical console. Calibration of non-invasive pressure and vacuum sensors in a cassette by utilizing a proportional cross-connect to pressurize the lines with set pressure or vacuum the lines with set vacuum and measure the response of respective sensors in the cassette. The use of proportional pressure may be used along with other clearing methods to clear material clogging the aspiration channel pathways and tubing of the surgical system. Utilize the cross-connect functionality to more rapidly pressurize the aspiration line upon detection or prediction of a post occlusion surge, thereby reducing the pressure difference between the surgical field, the eye chamber, and aspiration line which may prevent, for example, a surge of fluid out of the anterior chamber of the eye.

Abstract: In some embodiments, a fluid dynamics system includes a solenoid valve including a valve body including ports including an inlet port and an outlet port, and a valve cavity having a direction of elongation and configured to provide fluid connectivity between respective ones of the ports, a solenoid coil disposed in the valve body around valve cavity, and a plunger comprising a permanent magnet, and configured to move back-and-forth along the direction of elongation between a first position and a second position in the valve cavity selectively controlling the fluid connectivity between respective ones of the ports, and a controller configured to apply at least one current to the solenoid coil to selectively move the plunger between the first position and the second position, and to selectively maintain the plunger in the first position and the second position.

Abstract: A system of contact lenses includes at least two contact lenses, each lens having a visual correction for a non-rotationally symmetric eye aberration. Each lens has a different level or degree of a stabilization that is characterized by a thickness differential between a thickness of a stabilization zone and a thickness of a non-stabilization zone.

Abstract: A system includes (i) a solenoid valve, positioned between a handle of a probe, and an aspiration line coupled with the handle for aspirating fluids from the probe, the solenoid valve includes at least a solenoid coil and a plunger movable by the solenoid coil, (ii) a sensor, positioned between the handle and the aspiration line and configured to produce a signal indicative of a fluid metric in the aspiration line, and (iii) a controller, configured to identify, based on the signal, a vacuum surge in the aspiration line, and, in response to identifying the vacuum surge, to apply at least one current to the solenoid coil to selectively move the plunger between a first position and a second position, and to selectively maintain the plunger in the first position and the second position.

Abstract: In one embodiment, a fluid dynamics system includes a solenoid valve including a valve body including ports including an inlet and outlet port, and a valve cavity having a direction of elongation and configured to provide fluid connectivity between ones of the ports, a solenoid coil disposed around valve cavity, and a plunger including a permanent magnet, and configured to move back-and-forth along the direction of elongation between a first and a second position in the valve cavity selectively controlling the fluid connectivity between respective ones of the ports, the valve body including shock absorber(s) to soften striking of the plunger against the valve body in the direction of elongation, and a controller configured to apply at least one current to the solenoid coil to selectively move the plunger between the first and second position, and to selectively maintain the plunger in the first position and the second position.