Abstract: A biological hazard protection body bag comprises an non-transparent outer bag case and a transparent inner bag case, which transparent inner bag case provides a vacuum filtration device formed by a check valve and medical grade filter screen for achieving a vacuum state inside the inner space of the transparent inner bag case by air suction through the check valve of the vacuum filtration device, and the air extracted from the inner space of the transparent inner bag case is completely filtrated by the medical grade filter screen to prevent the pathogen from being extracted from the inner space of the transparent inner bag case to isolate the corpse inside the transparent inner bag case under nearly vacuum state with gastight bag case construction to achieve the purpose of prevent infection or dissemination of pathogen.