Patents Assigned to Kangwon National University Industry Cooperation Foundation
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Patent number: 11207363Abstract: The present invention provides a pharmaceutical composition for preventing or treating Alzheimer's disease and a food composition for relieving symptoms of Alzheimer's disease, which comprise a mountain-cultivated ginseng extract. The composition comprising the mountain-cultivated ginseng extract of the present invention is beneficially used as a pharmaceutical composition for preventing or treating Alzheimer's disease in the medical field for the treatment of Alzheimer's disease or as a food composition for relieving the symptoms of Alzheimer's disease.Type: GrantFiled: April 26, 2018Date of Patent: December 28, 2021Assignees: KANGWON NATIONAL UNIVERSITY INDUSTRY COOPERATION FOUNDATIONInventors: Sang Il Lee, Hyoung Chun Kim, Sung Kwon Ko, Eun Joo Shin
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Patent number: 10414736Abstract: Disclosed is a method of preparing ezetimibe, including cross-metathesis using a Grubbs 2nd catalyst and deprotection using a Pearlman's catalyst, and an intermediate thereof. The method of preparing ezetimibe is useful as an efficient ezetimibe synthesis technique in pharmaceutical fields using ezetimibe as a raw material.Type: GrantFiled: September 28, 2018Date of Patent: September 17, 2019Assignee: Kangwon National University Industry Cooperation FoundationInventors: Phil Ho Lee, Koo Yeon Lee, Yonghyeon Baek, Kyusik Um, Byeong Su Kim
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Patent number: 10150961Abstract: The present disclosure relates to a method for producing a monoclonal antibody that binds to an epitope for the glycan binding site of a glycoprotein. According to the present disclosure, a monoclonal antibody that recognizes the glycan binding site of a glycoprotein as an epitope can be produced in a relatively simple and economic manner, and a monoclonal antibody having high sensitivity and specificity for the glycan binding site of a glycoprotein can be produced. The monoclonal antibody produced according to the present disclosure can be effectively used as an agent for diagnosing or treating various diseases associated with a change in glycan structure or glycan expression level.Type: GrantFiled: July 19, 2013Date of Patent: December 11, 2018Assignees: Seoul National University R&DB Foundation, Kangwon National University Industry Cooperation FoundationInventors: Eugene C. Yi, Min Jueng Kang, Kristine M. Kim, Eunhee G. Kim
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Patent number: 9868874Abstract: Using the sympathetic printed-matter according to the present invention, a hidden content can be visualized just by wetting. Therefore, it is possible to remove necessities of the sympathetic ink and a special material such as reagent or equipment for visualizing hidden contents. In addition, since the hidden contents disappear by removing water from the sympathetic printed-matter, the sympathetic printed-matter can be used repeatedly. Using the reading confirmation portion, whether or not the sympathetic printed-matter has been read by any other person can be easily determined. In the sympathetic printing method according to the present invention, a hydrophobic substrate can be formed using an existing gas grafting facility, and an ester hydrolase composition and the reading confirmation portion can be formed using an existing printing method. Therefore, a large amount of sympathetic printed-matters can be produced inexpensively and efficiently.Type: GrantFiled: July 29, 2016Date of Patent: January 16, 2018Assignees: KANGWON NATIONAL UNIVERSITY-INDUSTRY COOPERATION FOUNDATION, DAEHAN PAPER CO., LTD., TAEKYUNG POLYMER CO., LTD., CENTRE TECHNIQUE DE L'INDUSTRIE DES PAPIERS, CARTONS ET CELLULOSESInventors: Myoung Ku Lee, Jeong Yong Ryu, Chang Geun Kim, Kwang Seob Lee, Jae Hoon Lee, Han Je Cho, Hyeok Jun Kwon, David Guerin, Philippe Martinez
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Patent number: 9249481Abstract: A preparation method of silver nanostructure for use as substrate of surface-enhanced Raman scattering (SERS), which can ensure the ‘hot spot’, which provides the considerably very intense electromagnetic field in which the silver nano-structures have uniform average size and very strong forms of particles, by characterizing a variety of conditions such as, for example, concentration of AgNO3 and reductant, reaction temperature, stirring velocity, single dropwise addition quantity, dropwise addition rate, or total dropwise addition quantity, which were unpredictable in the conventional silver nanoparticle preparation method using AgNO3 aqueous solution and NaBH4 reductant, so that the preparation method can be advantageously applied for the mass production of silver nano-structures for use as substrate of SERS because the method can provide multimer form with enhanced SERS signals and reproducibility, and also ability to selectively control the particle size.Type: GrantFiled: October 1, 2013Date of Patent: February 2, 2016Assignee: Kangwon National University-Industry Cooperation FoundationInventors: Chan Ho Kwon, So Young Eom, Hong Lae Kim
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Patent number: 8795890Abstract: Provided are an anode active material for a lithium secondary battery having high reversible capacity and excellent charge/discharge efficiency, comprising a complex composed of ultra-fine Si phase particles and an oxide surrounding the ultra-fine Si phase particles, and a carbon material; and a method for preparing the same. The present invention also provides a method for preparing an anode active material for a lithium secondary battery comprising producing a complex composed of ultra-fine Si particles and an oxide surrounding the ultra-fine Si particles by mixing a silicon oxide and a material having an absolute value of oxide formation enthalpy (?Hfor)greater than that of the silicon oxide and negative oxide formation enthalpy by a mechanochemical process or subjecting them to a thermochemical reaction to reduce the silicon oxide; and mixing the Si phase-containing oxide complex and carbon material.Type: GrantFiled: February 3, 2011Date of Patent: August 5, 2014Assignees: LG Chem, Ltd., Kangwon National University Industry Cooperation FoundationInventors: Sung-Man Lee, Heon Young Lee, Moon Ki Hong
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Publication number: 20140099513Abstract: A preparation method of silver nanostructure for use as substrate of surface-enhanced Raman scattering (SERS), which can ensure the ‘hot spot’, which provides the considerably very intense electromagnetic field in which the silver nano-structures have uniform average size and very strong forms of particles, by characterizing a variety of conditions such as, for example, concentration of AgNO3 and reductant, reaction temperature, stirring velocity, single dropwise addition quantity, dropwise addition rate, or total dropwise addition quantity, which were unpredictable in the conventional silver nanoparticle preparation method using AgNO3 aqueous solution and NaBH4 reductant, so that the preparation method can be advantageously applied for the mass production of silver nano-structures for use as substrate of SERS because the method can provide multimer form with enhanced SERS signals and reproducibility, and also ability to selectively control the particle size.Type: ApplicationFiled: October 1, 2013Publication date: April 10, 2014Applicant: KANGWON NATIONAL UNIVERSITY-INDUSTRY COOPERATION FOUNDATIONInventors: Chan Ho KWON, So Young EOM, Hong Lae KIM
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Patent number: 7906236Abstract: Provided are an anode active material for a lithium secondary battery having high reversible capacity and excellent charge/discharge efficiency, comprising a complex composed of ultra-fine Si phase particles and an oxide surrounding the ultra-fine Si phase particles, and a carbon material; and a method for preparing the same. The present invention also provides a method for preparing an anode active material for a lithium secondary battery comprising producing a complex composed of ultra-fine Si particles and an oxide surrounding the ultra-fine Si particles by mixing a silicon oxide and a material having an absolute value of oxide formation enthalpy (?Hfor) greater than that of the silicon oxide and negative oxide formation enthalpy by a mechanochemical process or subjecting them to a thermochemical reaction to reduce the silicon oxide; and mixing the Si phase-containing oxide complex and carbon material.Type: GrantFiled: July 29, 2004Date of Patent: March 15, 2011Assignees: LG Chem, Ltd., Kangwon National University Industry Cooperation FoundationInventors: Sung-Man Lee, Heon Young Lee, Moon Ki Hong