Abstract: This application relates to the field of neurodegenerative diseases, more particularly to the field of Parkinson's disease. In particular, the disclosure describes that inhibitors reducing FAS activity can be used for treatment of Parkinson's disease, in particular, the treatment of patients suffering from Parkinson's disease having loss of function mutations in PINK1 or PARKIN genes.
Type:
Grant
Filed:
November 20, 2015
Date of Patent:
December 21, 2021
Assignees:
VIB VZW, Katholieke Universiteit Leuven, KU Leuven R&E
Inventors:
Patrik Verstreken, Vanessa Morais Epifânio, Melissa Vos