Abstract: Described herein is a germ guard label and methods of using the same. A germ guard label at least substantially conformal to an oral transmission area of an object can prevent or limit transmission of contaminants like germs, for example, from person to person. When an infected person touches an object covered with a germ guard label, germs transmitted from the infected person can contaminate the germ guard label rather than the object. Another person can remove the contaminated germ guard label from the object, and the oral contact area of the object covered by the germ guard label can be substantially germ free. The germ guard label also can prevent spillage of a substance from the oral contact area.