Patents Assigned to Kisérleti Orvostudoányi Kutatóintézet
  • Transgenic mouse for the assessment of thyroid hormone (TH) action
    Patent number: 10694724
    Abstract: A transgenic animal model that is suitable for the cell or tissue specific assessing of thyroid hormone (TH) action in vivo is described. The recombinant DNA construct and methods suitable to generate such an animal are also provided. The assessment of TH action is based on a reporter that is dependent on an endogenously expressed thyroid hormone receptor (TR) and coregulators of said receptor.
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: June 30, 2020
    Assignee: Kisérleti Orvostudoányi Kutatóintézet
    Inventors: Csaba Fekete, Balázs Gereben, Petra Mohácsik, Ferenc Erdélyi, Gábor Szabó