Abstract: A non-invasive analyte sensor device that includes a sensor housing, and a decoupled antenna/detector array having at least one transmit antenna/element and at least one receive antenna/element. The sensor housing has a maximum length dimension no greater than 50 mm, a maximum width dimension no greater than 50 mm, a maximum thickness dimension no greater than 25 mm, and a total interior volume of no greater than about 62.5 cm3. In addition, the at least one transmit antenna/element and the at least one receive antenna/element have a maximum spacing therebetween that does not exceed 50 mm and a minimum spacing therebetween that is at least 1.0 mm, and the at least one transmit antenna/element and the at least one receive antenna/element are less than 95% coupled to one another, or less than 90% coupled to one another, or less than 85% coupled to one another, or less than 75% coupled to one another.

Abstract: An enhanced SPO2 measuring device which includes an optical SPO2 measurement subsystem, an RF SPO2 measurement subsystem, and an integration module that provides at least one of the following functions: a fusion module in which the optical data and RF data are fused to create new SPO2 data: a machine learning module that enhances the final SPO2 measurements; or an accuracy module that provides more accurate SPO2 data.

Abstract: A method for providing notification regarding one or more analytes includes detecting an amount of each of the one or more analytes using a non-invasive sensor, determining a notification to present based on the amount of at least one of the one or more analytes and notification criteria using a processor, and sending an instruction directing presentation of the notification. The method can further include presenting the notification. The notification can include vibration, sound, or visible components such as light, text, or images. The notification criteria can include upper thresholds, lower thresholds, or the analyte being within or outside of bounded ranges. Systems performing the method can include the sensor and optionally one or more of a mobile device and a remote server, and the notification can be presented in a device including the sensor or a separate device such as the mobile device.

Abstract: A method of operating a sensor system for detecting one or more analytes in a target includes preparing for an analyte scan of the target, generating an analyte scan that includes one or more frequencies in a radio or microwave range of the electromagnetic spectrum, and controlling a non-invasive sensor to implement the analyte scan of the target using. One or more of implementing a warm-up preparatory scan and/or detecting for external signal interference and the analyte scan being generated based on the detection for the external signal interference. A sensor system includes a non-invasive sensor and a controller for the non-invasive sensor. A sensor system includes a non-invasive sensor and one or more auxiliary sensors communicatively connected to the non-invasive sensor.

Abstract: Methods for determining variability in a state of a medium, include monitoring the medium and determining the variability in the state of the medium based on the processing of the response over time based on the response detected at the at least one receive element over time. Monitoring the medium can include generating a transmit signal, transmitting it into the medium using a transmit element, and receiving a signal from the medium at a receive element. The transmit and receive elements can be decoupled from one another. The transmit and receive elements can have differing geometry. The determined variability in the state of the medium can be used to provide notifications and/or take automated actions.

Abstract: An analyte sensor that detects an analyte via spectroscopic techniques using frequencies in the radio or microwave frequency range of the electromagnetic spectrum. The analyte sensor is configured to permit adjustment of the position(s) of one or more transmit components and/or the position(s) of one or more receive components. Adjusting position (or the like) as used in the description and claims includes changing an angle of the transmit component(s) and/or the receive component(s), and/or moving the transmit component(s) and/or the receive component(s) in one or more X, Y, Z directions, and/or changing a shape of the transmit component(s) and/or the receive component(s), and any combinations thereof.

Abstract: Systems for determining a variability in a state of a medium include one or more transmit elements or antennas and one or more receive elements or antennas which are relatively decoupled from one another. The transmit and receive elements or antennas can be less than 95% coupled to one another. The system also includes a transmit circuit configured to generate a transmit signal to be transmitted, which is in a radio or microwave frequency range of the electromagnetic spectrum. The system also includes a receive circuit configured to receive a response detected by the at least one receive antenna resulting from transmission of the transmit signal into the medium. The system includes a processor configured to determine the variability in the state of the medium based on processing of the response over time. The variability can further be used to direct notifications or automated actions.

Abstract: Consumable and replaceable light bulbs that emit white light to provide ambient lighting and also emit UV light for pathogen inactivation. The white light and the UV light may be emitted simultaneously or the light bulb can be controlled to emit the white light and the UV light at separate times. The UV light emitted by the light bulbs has a wavelength and output power that is safe for humans and pets and the UV light inactivates pathogens over relatively prolonged exposure periods. The light bulbs described herein can be used in place of conventional light bulbs, for example in a room of a home, office building or other human occupied space. Humans can remain in the space when the light bulb(s) is on without being harmed by the UV light.

Abstract: A highly accurate glucose sensor that detects glucose by transmitting and receiving sensing signals in a radio or microwave frequency range of the electromagnetic spectrum is provided. The glucose sensor has at least two antennas at least one of which operates as a transmit antenna to transmit one or more of the sensing signals and at least one of which operates as a receive antenna, and the glucose sensor has a mean absolute relative difference (MARD) value of about 5.0% to about 9.9%, or of about 5.0% to about 7.0%, or of about 5.0%.

Abstract: Analyte sensing and response systems include a sensor detecting one or more analytes in a medium. The sensor uses decoupled transmit and receive elements or antennas to transmit a signal into the medium, and receive a response to the transmitted signal. An action that is based on the detection of the analyte is generated which can directly or indirectly affect the detected analyte in the medium. The action is automatically performed. The action can be increasing or decreasing flow from a source of the analyte, or of a chemical compound interacting with the analyte. An example of the action is controlling an insulin pump, where the analyte is glucose.

Abstract: Analyte sensing and response methods include using a non-invasive analyte sensor to detect at least one analyte in a medium. The sensor uses decoupled transmit and receive elements or antennas to transmit a signal, and to receive a response to the signal transmitted into the medium. An action is determined based on the detection of the analyte, which can affect a property of the analyte or the medium, and the action is automatically carried out. The action can be increasing or decreasing flow from a source of the analyte, increasing or decreasing flow of a chemical compound interacting with the analyte, or modifying a temperature of the medium. An example of the action is controlling an insulin pump, where the analyte is glucose.

Abstract: A method of detection of an analyte includes implementing a scan routine using a detector array that is electrically connected to a transmit circuit and electrically connected to a receive circuit, the detector array having at least three detector elements. In a first scan, a first combination of the detector elements is used to transmit a first transmit signal that is in a radio or microwave frequency or visible range of the electromagnetic spectrum into a target containing at least one analyte of interest and used to detect a response resulting from transmission of the first transmit signal into the target. In a second scan, a second combination of the detector elements, different from the first combination, is used to transmit a second transmit signal that is in a radio or microwave frequency or visible range of the electromagnetic spectrum into the target and is used to detect a response resulting from transmission of the second transmit signal into the target.

Abstract: Establishing an analyte database using analyte data that has been obtained using one or more non-invasive analyte sensors, and using the analyte database to analyze data obtained using a non-invasive analyte sensor. Once the analyte database is established, the analyte database can be updated with new analyte data, and the analyte database can be used to analyze the new analyte data to derive information from the new analyte data. For example, in the case of a human target, the new analyte data together with the analyte database can be used to predict an actual or possible abnormal medical pathology of the human target.

Abstract: Establishing an analyte database using analyte data that has been obtained using non-invasive analyte sensors, and using the analyte database to analyze data obtained using a non-invasive analyte sensor. Once the analyte database is established, the analyte database can be updated with new analyte data, and the analyte database can be used to analyze the new analyte data to derive information from the new analyte data. For example, in the case of a human target, the new analyte data together with the analyte database can be used to predict an actual or possible abnormal medical pathology of the human target.

Abstract: Establishing an analyte database using analyte data that has been obtained using non-invasive analyte sensors, and using the analyte database to analyze data obtained using a non-invasive analyte sensor. Once the analyte database is established, the analyte database can be updated with new analyte data, and the analyte database can be used to analyze the new analyte data to derive information from the new analyte data. For example, in the case of a human target, the new analyte data together with the analyte database can be used to predict an actual or possible abnormal medical pathology of the human target.

Abstract: A method of non-invasive detection of an analyte includes generating a transmit signal having at least two different frequencies each of which is in a radio or microwave frequency range of the electromagnetic spectrum, and transmitting the transmit signal into a target containing at least one analyte of interest using at least one transmit antenna/element. At least one receive antenna/element that is decoupled from the at least one transmit antenna/element is used to detect a response resulting from transmitting the transmit signal by the at least one transmit antenna/element into the target containing the at least one analyte of interest. In one embodiment, the at least one transmit antenna/element can have a first geometry and the at least one receive antenna/element can have a second geometry that is geometrically different from the first geometry.