Abstract: The invention provides monoclonal antibodies, which specifically react with a Fas ligand, or active fragments thereof, a production process of the monoclonal antibodies, which specifically react with a Fas ligand, hybridomas separately producing a monoclonal antibody, which specifically reacts with a Fas ligand present on a cell surface, a method of detecting a Fas ligand in a solution, and a kit for use in detecting a Fas ligand, comprising plurality of monoclonal antibodies against Fas ligand in combination.
Type:
Grant
Filed:
March 21, 1996
Date of Patent:
September 20, 2005
Assignee:
Ko Okumura
Inventors:
Nobuhiko Kayagaki, Hideo Yagita, Ko Okumura, Motomi Nakata