Patents Assigned to Korea Institute of Science and Technology
  • Implant having controlled generation rate of reactive oxygen species and method of controlling generation of reactive oxygen species using the same
    Patent number: 11738123
    Abstract: Provided is an implant having a controlled generation rate of reactive oxygen species and a method of controlling generation of reactive oxygen species using the same. The implant having a controlled generation rate of reactive oxygen species according to the present invention includes a body formed of a metallic material and having a groove, a first filling metal filling one region of the groove, and a second filling metal filling the groove on the first filling metal, wherein the second filling metal has an ionization tendency different from that of the first filling metal.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: August 29, 2023
    Assignees: Korea Institute of Science and Technology, Korea University Research and Business Foundation
    Inventors: Myoung-Ryul Ok, Jimin Park, Yu Chan Kim, Hyun Kwang Seok, Hyung-Seop Han, Hojeong Jeon, Hyunseon Seo, Jee-Wook Lee, Jin Kyung Jeon, Gayoung Jung, Jong Woong Park, Ji Hun Park
  • Early and non invasive method for assessing a subject's risk of having pancreatic ductal adenocarcinoma and methods of treatment of such disease
    Patent number: 11740243
    Abstract: A non invasive diagnostic method of pancreatic ductal adenocarcinoma (PDAC) in a subject is provided. The method comprises the step of measuring the level of ?ig-h3 protein in a blood sample wherein the serum level of ?ig-h3 is positively correlated with the risk of having a PDAC. By following studies on 2 distinct cohorts of 20 and 104 of PDAC patients, and on PDAC mouse model, the inventors show that ?ig-h3 can be directly detected in the blood sample and ?ig-h3 is expressed very early in tumorigenesis in pancreatic neoplastic lesions. Also provided is a ?ig-h3 protein, for use in the treatment of PDAC. The inventors found that ?ig-h3 bind directly on CD8+ T cells by reducing their activation and cytotoxic properties. Furthermore, the use of neutralizing ?ig-h3 antibodies in PDAC mouse model reduced tumor growth by enhancing CD8+ T cell anti-tumoral response.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: August 29, 2023
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ CLAUDE BERNARD—LYON, CENTRE LEON BERARD, KIST (KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY)
    Inventors: Kim In-San, Philippe Bertolino, Ana Hennino
  • NEUROMORPHIC SYSTEM FOR IMPLEMENTING SPIKE TIMING DEPENDENT PLASTICITY OPERATION
    Publication number: 20230267318
    Abstract: Provided is a neuromorphic system for synaptic learning in a spiking neural network (SNN)-based neuromorphic array structure. Control blocks including a post-synaptic neuron, which generates a post-neuron spike, are disposed on output lines of a synapse array to implement a spike timing dependent plasticity (STDP) operation such that synaptic learning can be stably implemented in an SNN neuromorphic array. Also, a lateral inhibition circuit may be added. When a post-neuron spike is generated by an STDP control block connected to any one output line, the lateral inhibition circuit inhibits STDP control blocks connected to other output lines from generating spikes. Accordingly, learning selectivity can be improved, and thus the performance of an STDP algorithm can be improved.
    Type: Application
    Filed: July 25, 2022
    Publication date: August 24, 2023
    Applicant: Korea Institute of Science and Technology
    Inventors: Joon Young KWAK, Sung Yun PARK, Min Jee KIM, Su Youn LEE
  • Smart wearable lens mounted with all-solid-state thin film secondary battery and method for manufacturing the same
    Patent number: 11733543
    Abstract: Disclosed herein is a smart wearable lens mounted with an all-solid-state thin film secondary battery including a flexible substrate, a cathode current collector, a cathode, a solid electrolyte, an anode, and an anode current collector. The smart wearable lens mounted with the all-solid-state thin film secondary battery may be stably and continuously supplied with power and has a low self-discharge rate. In addition, the smart wearable lens may minimize aversion when humans are wearing the smart wearable lens and be suitably used for a curved lens, especially a micro-lens such as a contact lens.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: August 22, 2023
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Ji-Won Choi, Yong-Won Song, Hyunjung Yi, Jin Sang Kim, Chong Yun Kang, Seong Keun Kim, Seung Hyub Baek, Sang Tae Kim, Hyun Seok Lee
  • Method for supporting X-RAY image reading using image transform model and system performing the same
    Patent number: 11734831
    Abstract: Embodiments relate to a method for supporting X-ray image reading including receiving information associated with a reading target positioned in a reading space where X-rays pass through or are reflected off, acquiring a non X-RAY image of an item object based on the information associated with the reading target, and generating a fake X-RAY image of the item object by applying the non X-RAY image of the item object to the image transform model, and a system for performing the same.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: August 22, 2023
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Junghyun Cho, Ig Jae Kim, Hyunwoo Cho, Haesol Park
  • System and method for calibrating ratio of body size of subject
    Patent number: 11730394
    Abstract: Embodiments relate to a system and method for calibrating a ratio of body size of a subject including setting a body coordinate system of each body segment of the subject, calculating a first rotation matrix from a world coordinate system set based on the ground to a sensor coordinate system of each motion sensor when the subject takes a first basic pose, calculating a second rotation matrix from the world coordinate system to the sensor coordinate system of each motion sensor when the subject takes a second basic pose, calculating a third rotation matrix from the world coordinate system to the body coordinate system of a trunk for a first motion sensor attached to the trunk of the subject, and calculating a ratio of body size of the subject based on the third rotation matrix.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: August 22, 2023
    Assignee: Korea Institute of Science and Technology
    Inventors: Donghoon Kang, Jinwook Kim
  • Silver nanowire-mesh (Ag NW-mesh) electrode and manufacturing method thereof
    Patent number: 11735330
    Abstract: According to one aspect of the present invention, a silver nanowire mesh (Ag NW-mesh) electrode and a fabricating method thereof. The Ag NW-mesh electrode includes a flexible substrate; and a mesh pattern layer which is disposed on the flexible substrate and in which a plurality of first meal lines and a plurality of second metal lines are composed of Ag NWs and intersect each other in an orthogonal or diagonal direction to form a grid pattern, wherein the first metal lines and the second metal lines of the mesh pattern layer form an angle of 35 degrees to 55 degrees with respect to a bending direction.
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: August 22, 2023
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sang Woo Kim, Seong Jun Kim
  • ELECTROMAGNETIC SHAPE SENSOR INTEGRATED WITH WIRE-DRIVEN ROBOT
    Publication number: 20230256628
    Abstract: Provided is an electromagnetic shape sensor integrated with a wire-driven robot. The electromagnetic shape sensor for sensing a shape of the wire-driven robot according to the embodiment includes an excitation coil configured to surround at least a part of an outer peripheral surface of the tube, and a plurality of sensing coils configured to each surround at least a part of an outer peripheral surface of the wire.
    Type: Application
    Filed: February 8, 2023
    Publication date: August 17, 2023
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jiyun JEON, Chunwoo KIM
  • CATALYST FOR A DEHYDROGENATION REACTION, A MANUFACTURING METHOD THEREOF, AND A HYDROGEN PRODUCTION METHOD USING SAME
    Publication number: 20230256419
    Abstract: A catalyst for a dehydrogenation reaction includes a carrier including Al2O3 having a theta (?) phase, an active metal supported on the carrier and including a noble metal, and an auxiliary metal supported on the carrier and different from the active metal.
    Type: Application
    Filed: July 12, 2022
    Publication date: August 17, 2023
    Applicants: HYUNDAI MOTOR COMPANY, KIA CORPORATION, KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Pyung Soon Kim, Jin Woo Choung, Yongwoo Kim, Jihui Seo, Jaeyong Lee, Sungeun Moon, Changil Ahn, Suk Woo Nam, Hyuntae Sohn, Yongmin Kim, Hyangsoo Jeong
  • Synthesis of metal oxide catalysts using supercritical carbon dioxide extraction
    Patent number: 11724252
    Abstract: A metal oxide catalyst synthesized using supercritical carbon dioxide extraction is provided, wherein the metal oxide catalyst includes an active site containing at least one type of metal oxide and a support for loading the active site and the metal oxide is an oxide of a metal selected from the group consisting of transition metals (atomic number 21 to 29, 39 to 47, 72 to 79, or 104 to 108), lanthanide (atomic number 57 to 71), post-transition metals (atomic number 13, 30 to 31, 48 to 50, 80 to 84, and 112), and metalloids (atomic number 14, 32 to 33, 51 to 52, and 85) in the periodic table, and a combination thereof.
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: August 15, 2023
    Assignee: Korea Institute of Science and Technology
    Inventors: Jongsik Kim, Heon Phil Ha
  • COMPOSITION FOR REGULATING EXPRESSION OF PROX1 OR EXPRESSION OF TELOMERASE REVERSE TRANSCRIPTASE COMPRISING ACTIVITY REGULATOR OR METHOD FOR SCREENING TELOMERASE REVERSE TRANSCRIPTASE REGULATOR
    Publication number: 20230250424
    Abstract: In the present specification, on the basis of the correlation between prospero homeobox protein 1 (PROX1) and telomerase reverse transcriptase (TERT), a composition for regulating expression of TERT, a method for screening a TERT expression regulator, a composition for diagnosing a TERT expression status, a diagnostic kit, a method for providing information for diagnosis, or a method for providing information for cancer diagnosis are disclosed. Specifically, in one aspect, the PROX1 of the present disclosure may bind to a TERT promoter, in particular a mutant TERT promoter in which base substitution occurs at the -124 or -146 bp position to regulate the expression of TERT, and the expression of TERT in non-hepatitis B virus-associated liver cancer can be inhibited specifically among liver cancers.
    Type: Application
    Filed: October 19, 2018
    Publication date: August 10, 2023
    Applicants: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
    Inventors: Sang Hoon JUNG, Young-Joo KIM, Dae-geun SONG, Young Nyun PARK, Jeong Eun YOO, Hyung Jin RHEE, Youngsic JEON
  • 3D HUMAN BODY JOINT ANGLE PREDICTION METHOD AND SYSTEM USING 2D IMAGE
    Publication number: 20230248261
    Abstract: A system for predicting a three-dimensional human body joint angle according to an embodiment predicts information on a human body joint angle of a new subject by photographing a motion of a subject at different three-dimensional positions and using information on the human body joint angle according to the generated motion of the subject and information on the human body joint angle according to the motion of the subject.
    Type: Application
    Filed: October 31, 2022
    Publication date: August 10, 2023
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kyung-Ryoul MUN, Jinwook KIM
  • Method of continuously producing cannabinol from cannabis plant and uses thereof
    Patent number: 11717474
    Abstract: Provided are: a method of preparing a cannabis processed product having an increased CBN content in an efficient and economic manner, through cyclization of CBD and aromatization of THC by continuous microwave irradiation of a cannabis extract; and use of a processed product having an increased CBN content prepared by the method, a fraction thereof, and a single ingredient of CBN, in foods, drugs, and cosmetics.
    Type: Grant
    Filed: December 30, 2020
    Date of Patent: August 8, 2023
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jungyeob Ham, Taejung Kim, Bong Chul Chung, Sungdo Ha, Seok Lee, Jin-Chul Kim, Pilju Choi, Bong Geun Song
  • Method of improving thermoelectric performance of SnSe thermoelectric material
    Patent number: 11723273
    Abstract: Provided is a method of preparing an SnSe thermoelectric material including (a) heating a mixture including Sn2+ and Se2?, (b) cooling the mixture at a cooling rate greater than 0 and equal to or less than 3 K/h, and forming single crystal Sn1-xSe (where 0<x<1), and an SnSe thermoelectric material prepared thereby and including Sn vacancies.
    Type: Grant
    Filed: December 14, 2021
    Date of Patent: August 8, 2023
    Assignees: Korea Institute of Science and Technology, Pusan National University Industry-University Cooperation Foundation
    Inventors: Hyejin Ryu, Choongyu Hwang, Kyoo Kim
  • Apparatus for evaluating high-temperature creep behavior of metals, and method of evaluating the same
    Patent number: 11714036
    Abstract: Provided is an apparatus for evaluating high-temperature creep behavior of metals, the apparatus including a chamber configured to fix a metal sample in an inner space sealed from an external environment, and including, at a lower portion, a metal tube stretchable in a length direction by a pressure of a gas, wherein the apparatus is configured in such a manner that a load received by the chamber in the length direction due to the pressure of the gas injected into the chamber is applied to the metal sample.
    Type: Grant
    Filed: November 4, 2020
    Date of Patent: August 1, 2023
    Assignee: Korea Institute of Science and Technology
    Inventors: Jin-Yoo Suh, Han-Jin Kim, Young Whan Cho, Woo Sang Jung, Jae-Hyeok Shim, Dong-Ik Kim, Young-Su Lee, Jihyun Hong
  • Antiviral composition for SARS-CoV-2 containing cannabinoids as active ingredient
    Patent number: 11707444
    Abstract: The present invention relates to an antiviral composition and a screening method thereof for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that occurred in Wuhan, China in 2019. An extract from leaves or unfertilized female flowers of Cannabis sativa L. or its fraction, and the cannabinoids (CBDs) molecules isolated from it have high binding strength and stability to SARS-CoV-2 MPpro, thereby inhibiting its action as the main protease, to provide a useful lead molecule that can be used alone or in combination with other drugs to treat SARS-CoV-2.
    Type: Grant
    Filed: September 3, 2021
    Date of Patent: July 25, 2023
    Assignees: RESEARCH COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY, KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jintae Lee, Jungyeob Ham, Taejung Kim
  • TERNARY PHOTOACTIVE LAYER COMPOSITION AND ORGANIC SOLAR CELL COMPRISING SAME
    Publication number: 20230227473
    Abstract: The present disclosure relates to a ternary photoactive layer composition and an organic solar cell including the same. According to the present disclosure, excessive crystal growth and aggregation can be prevented during large-area coating of a photoactive layer, uniform morphology can be achieved without significant phase separation, an organic solar cell with superior photovoltaic cell characteristics can be realized, and superior performance may be maintained even after long-term exposure to heat by preventing the morphological change of the photoactive layer.
    Type: Application
    Filed: August 9, 2022
    Publication date: July 20, 2023
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hae Jung SON, Sungmin PARK, So Hyun PARK, Hyunjung JIN, Hyeonggeun YU, Jai Kyeong KIM, Seongwon YOON
  • SMART SLING FOR PATIENT TRANSFER ASSISTANCE
    Publication number: 20230225921
    Abstract: A smart sling for patient transfer assistance includes a first driving unit, a second driving unit, a wire part and a sling unit. The first driving unit is configured to provide a rotational driving force. The second driving unit is spaced apart from the first driving unit by a predetermined distance. The wire part extends between the first driving unit and the second driving unit. The sling unit is configured to unfold toward the second driving unit from a folded state into the first driving unit along the wire part, to position a patient on the sling unit.
    Type: Application
    Filed: January 13, 2023
    Publication date: July 20, 2023
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyunki IN, Myungjoong LEE, Yonghwan MOON, Keri KIM
  • High efficiency and high sensitivity particle capture type terahertz sensing system
    Patent number: 11703442
    Abstract: Provided is a high efficiency and high sensitivity particle capture type terahertz sensing system. The particle capture type terahertz sensing system includes a sensing substrate to capture particles, and a terahertz sensor to emit terahertz electromagnetic waves to the sensing substrate to sense the particles, wherein the sensing substrate includes a base substrate and a particle capture structure layer formed on the base substrate, the particle capture structure layer includes a plurality of slits for focusing the terahertz electromagnetic waves, the particle capture structure layer captures the particles in the plurality of slits using dielectrophoresis, and an area in which the terahertz electromagnetic waves converge to the plurality of slits matches an area in which the particles are captured in the plurality of slits through the dielectrophoresis.
    Type: Grant
    Filed: December 31, 2020
    Date of Patent: July 18, 2023
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Minah Seo, Yong-Sang Ryu, Eui-Sang Yu, Taikjin Lee, Hyun Seok Song
  • Method of manufacturing and modularizing assembled thermal management material based on diamond-graphene hybrid structure
    Patent number: 11702736
    Abstract: Provided are a method of manufacturing a diamond-graphene hybrid heat spreader-thermal interface material assembled thermal management material including: (a) preparing a planar diamond base material; and (b) converting a predetermined thickness of at least a partial area of one side or both sides of the diamond base material into vertical graphene, wherein the diamond base material serves as a heat spreader, and a graphene layer formed on the diamond base material serves as a thermal interface material (TIM) or a heat sink, and a method of modulating the diamond-graphene hybrid thermal management material including modulating the thermal management material by attaching a heterogenous member to the surface of the diamond-graphene hybrid thermal management material and pressurizing the attached structure.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: July 18, 2023
    Assignee: Korea Institute of Science and Technology
    Inventors: Jae Kap Lee, Hyunsu Ju