Abstract: The present invention relates to an anti-inflammatory composition comprising Epimedium koreanum Nakai, Polygala tenuifolia Willd, and Polyporus umbellatus Fries extracts or a mixture thereof as an active ingredient. The extracts and mixture prepared according to the present invention exhibit a high inhibitory effect against nitric oxide and a suppressive effect against the expression of iNOS and COX2 and thus can be advantageously used as an anti-inflammatory composition.
Type:
Application
Filed:
March 19, 2021
Publication date:
May 9, 2024
Applicant:
Korea Research Institute of Chemical Technology
Inventors:
Hyoung-Yun Han, Jung-Hwa Oh, Seokjoo Yoon, Se-Myo Park, Mi-Sun Choi, Soojin Kim
Abstract: The present invention relates to an isoindolin-1-on derivative, a method for preparing same, and a pharmaceutical composition comprising same as an effective component for preventing or treating tumors, wherein the isoindolin-1-on derivative exhibits a high inhibitory effect on EGFR mutations, and thus can be beneficially used for the treatment of EGFR-mutated tumors, and the isoindolin-1-on derivative exhibits a significant synergistic effect when co-administered, and thus can be beneficially used in concomitant therapy.
Type:
Grant
Filed:
August 12, 2019
Date of Patent:
May 7, 2024
Assignee:
Korea Research Institute of Chemical Technology
Inventors:
Kwangho Lee, Gildon Choi, Seoyoung Lee, Jiwon Kim, Byoung Chul Cho, Chae Won Park, Jiyeon Yun
Abstract: Disclosed is a small animal intraventricular injection compensator for injecting a drug into a desired location through a syringe, the compensator including: a guide part provided with a guide hole into which a needle of a syringe is inserted; a body comprising an upper cavity provided inside thereof and a cradle provided to seat the guide part on an upper side thereof; and a fixation part integrally provided with the body or separately provided, and comprising a lower cavity provided to allow a head accommodation space, which a head of a small animal may enter into or exit from, to be provided inside thereof by corresponding to the upper cavity.
Type:
Grant
Filed:
July 18, 2019
Date of Patent:
May 7, 2024
Assignees:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Sung Gurl Park, Kang Hyun Han, Chang Mook Lim, So Ra Park, Hong Su Lee, Jae Bong Lee, Jung Ho Noh, Sang Seop Han
Abstract: The present disclosure relates to a catalyst for ammonia decomposition, a manufacturing method therefor, and a method for producing hydrogen using the same. More particularly, the present disclosure relates to a catalyst for ammonia decomposition, a manufacturing method therefor, and a method for producing hydrogen using the same, in which by manufacturing a catalyst for decomposition of ammonia using a solvothermal synthesis method to which alcohol is applied, an ammonia conversion rate can be improved due to excellent catalytic activity in an ammonia decomposition reaction, and hydrogen can be efficiently produced from ammonia due to long-term stability even at a high temperature and for long periods of time.
Type:
Application
Filed:
March 10, 2022
Publication date:
May 2, 2024
Applicant:
Korea Research Institute of Chemical Technology
Inventors:
Ho Jeong Chae, Youngmin Kim, Thien An Le, Jeong-Rang Kim, Tae Wan Kim
Abstract: The present invention relates to a VOC reduction system and a VOC reduction method that applies pulse type thermal energy to a catalyst to activate the catalyst and oxidizes and removes the VOC.
Type:
Grant
Filed:
February 20, 2020
Date of Patent:
April 23, 2024
Assignee:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Jin Hee Lee, Iljeong Heo, Tae Sun Chang, Ji Hoon Park, Sang Joon Kim, Young Jin Kim
Abstract: The present invention relates to a benzothiazole or benzimidazole derivative, a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising same as an active ingredient for prevention or treatment of SIRTUIN 7 protein-related diseases. With excellent inhibitory activity against SIRTUIN 7 protein the derivative can be used for preventing or treating SIRTUIN 7 protein-related diseases.
Type:
Application
Filed:
January 21, 2022
Publication date:
April 11, 2024
Applicant:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Kwang Rok KIM, Kwan Young JEONG, Hee Jung JUNG, Doyoun KIM, Junmi LEE, Sang Dal RHEE, Kyu Myung LEE
Abstract: Provided is a method for synthesizing bipyridine that includes performing a dimerization reaction of a reactant including a piperidine-based compound, a pyridine-based compound, or a mixture thereof in the presence of a catalyst in which an active metal is supported on a composite metal oxide support including silica (SiO2) and alumina (Al2O3).
Type:
Grant
Filed:
August 22, 2022
Date of Patent:
April 9, 2024
Assignees:
HYUNDAI MOTOR COMPANY, KIA CORPORATION, KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Jihui Seo, Jaeyong Lee, Pyung Soon Kim, Jin Woo Choung, Yongwoo Kim, Ji Hoon Park, Soo Min Kim, Jeong Jae Lee, Kwanyong Jeong
Abstract: The present invention relates to a composition for forming a composite polymer film, a method for preparing the composition for forming a composite polymer film, a composite polymer film and a method for preparing the composite polymer film. The composition for forming a composite polymer film comprises: a fluorine-based polymer solution comprising a fluorine-based polymer; and polyvinylidene fluoride nanoparticles dispersed in the fluorine-based polymer solution. The method for preparing the composition for forming a composite polymer film comprises the steps of: preparing a fluorine-based polymer solution comprising a fluorine-based polymer; and dispersing polyvinylidene fluoride nanoparticles in the fluorine-based polymer solution. The composite polymer film comprises: a polymer matrix formed from a fluorine-based polymer; and polyvinylidene fluoride nanoparticles dispersed in the polymer matrix.
Type:
Application
Filed:
September 4, 2020
Publication date:
March 28, 2024
Applicants:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Eun Ho SOHN, Shin Hong YOOK, Hong Suk KANG, In Joon PARK, Sang Goo LEE, Soo Bok LEE, Won Wook SO, Hyeon Jun HEO, Dong Je HAN, Seon Woo KIM
Abstract: A light-emitting plasma lamp bulb for solar ultraviolet simulation includes a bulb cover having a spherical shape or a rod shape through which ultraviolet rays are transmittable, discharge gas contained in the bulb cover, and a first light-emitting material and a second light-emitting material, wherein the first light-emitting material includes at least one of mercury (Hg) and mercury iodide (HgI2), and the second light-emitting material includes sulfur (S8), wherein light emitted from the bulb has a maximum optical power intensity in a range of 395 to 455 nm which is an ultraviolet-visible boundary region, wherein, when compared using a same ultraviolet dose in an ultraviolet region of 290 to 400 nm, an integrated intensity of a visible and infrared region of 400 to 850 nm is equal to or less than ? of an integrated intensity of a visible and infrared region of a standard solar spectrum (ASTM G173, AM 1.5G).
Type:
Application
Filed:
August 16, 2023
Publication date:
February 22, 2024
Applicant:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Abstract: Proposed are a coordination complex compound-ZIF complex and a method of preparing the same. More particularly, proposed are a coordination complex compound-ZIF complex, which is a complex on which a coordination complex compound is supported by being chemically and directly bonded to a metal vacancy site of a ZIF, capable of being usable as a heterogeneous catalyst that can be recovered and reused in subsequent processes and maintaining catalytic functions of the coordination complex compound, which is an active ingredient, and to a method of preparing the same.
Type:
Application
Filed:
August 15, 2023
Publication date:
February 22, 2024
Applicant:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Young Kyu HWANG, Chang Ho YOO, Kyung Ryul OH, Dong Won HWANG, Gwang Nam YUN, Mi Jung LEE
Abstract: The present invention relates to a novel isoquinoline derivative, a preparing method thereof, and a pharmaceutical composition for preventing or treating autophagy related diseases containing the same as an active ingredient. The novel isoquinoline furanone derivative according to the present invention is capable of regulating autophagy activity, and thus, by using this derivative as an active ingredient, there is a useful effect that can be used as a pharmaceutical composition for preventing or treating autophagy-related diseases such as neurodegenerative diseases, cancer, metabolic diseases, inflammatory diseases or melanogenesis-related diseases, a health functional food composition for ameliorating thereof, or a cosmetic composition with a whitening function.
Type:
Grant
Filed:
July 2, 2021
Date of Patent:
January 23, 2024
Assignee:
Korea Research Institute of Chemical Technology
Inventors:
Myung-Ae Bae, Dae-Seop Shin, Jung Yoon Yang, Kyu Seok Hwang, Seong Soon Kim, Byung Hoi Lee, Ki Young Kim, Won Hoon Jung, Jae Chun Woo
Abstract: Disclosed is a catalyst for producing an olefin including an oxygen carrier material and a dehydrogenation catalyst. The catalyst allows hydrogen to be converted into water by using oxygen inside the lattice of an oxide catalyst without the additional supply of oxygen, and thus, the conversion can be increased while the decrease in selectivity, which is a disadvantage of an additional oxidative dehydrogenation reaction (ODHP), is suppressed.
Type:
Grant
Filed:
May 14, 2019
Date of Patent:
January 9, 2024
Assignees:
SK GAS CO., LTD., KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Yong Ki Park, Won Choon Choi, Daesung Park, Hawon Park, Changyeol Song, Deuk Soo Park, Ung Gi Hong, Miyoung Lee
Abstract: The present disclosure relates to a bifunctional catalyst for manufacturing a hydrocarbon from carbon dioxide and hydrogen. The bifunctional catalyst includes a carbon composite including cobalt (Co) and nitrogen (N) atoms forming a coordinate bond with the cobalt, and metal particles which exhibit a catalytic activity for a Fischer-Tropsch synthesis reaction and which are dispersed on the inner pore surface and/or the outer surface of the carbon composite support, thus simultaneously promoting a reverse water gas shift reaction and the Fischer-Tropsch synthesis reaction.
Type:
Grant
Filed:
January 23, 2020
Date of Patent:
January 9, 2024
Assignee:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Sun Mi Hwang, Ki Won Jun, Seok Ki Kim, Hae Gu Park, Seung Ju Han
Abstract: Provided are a recombinant microorganism, a composition comprising the same, and a method of producing a target product by using the same, the recombinant microorganism comprising a polynucleotide encoding a target product-binding protein fused to a secretion signal sequence.
Type:
Application
Filed:
July 8, 2021
Publication date:
January 4, 2024
Applicant:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Abstract: The present invention relates to an accelerated degradation test for testing durability of a specimen by rapidly inducing a failure or degradation rate according to use environmental factors, such as temperature and humidity, and more particularly, to an automated test device and test method for a complex accelerated degradation test, capable of various and precise accelerated degradation tests by constructing a multi-test environment in a single device and automating a process of putting pre-test specimens formed of chemical materials into a test environment, transferring the specimens to other test environments, and storing tested specimens in a storage chamber.
Type:
Application
Filed:
November 15, 2021
Publication date:
December 28, 2023
Applicants:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, AB NEXO CO., LTD
Inventors:
Doo Jin BYUN, Ho JUNG, Youngho PARK, Hyosang EOM
Abstract: Disclosed herein are an activated carbon catalyst for hydrogen peroxide decomposition, a preparation method thereof and a hydrogen peroxide decomposition method using the same. The activated carbon catalyst for hydrogen peroxide decomposition, provided in an aspect of the present invention may be easily prepared through the carbonization and activation of an ion exchange resin, and safer and higher decomposition efficiency of hydrogen peroxide may be achieved than the conventional catalyst for hydrogen peroxide decomposition through the control of the manganese content and pore properties in the catalyst.
Type:
Grant
Filed:
October 31, 2019
Date of Patent:
December 26, 2023
Assignee:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Jeong Kwon Suh, Ji Sook Hong, Iljeong Heo
Abstract: The present invention relates to a BCDA-based semi-alicyclic homo- or co-polyimide membrane material for gas separation and a preparation method thereof. The polyimide material prepared according to the present invention has high solubility in casting solvents, particularly in polar organic solvents, by interrupting asymmetry in the polyimide chain structure and formation of polyimide complexes compared with aromatic polyimides, and has higher heat resistance than the conventional aromatic polyimides and aliphatic polyimides, so that it is useful for the process of a high-selective permeable composite membrane or a asymmetric hollow fiber membrane used for commercial purposes, suggesting that it can be effectively used as a membrane for gas separation in various fields. In addition, the polyimide material membrane for gas separation of the present invention is useful because it has superior gas separation properties to the conventional commercialized aromatic polyimides or semi-alicyclic polyimides.
Type:
Grant
Filed:
November 20, 2019
Date of Patent:
December 26, 2023
Assignee:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Jeong Hoon Kim, Bong Jun Chang, Simon MoonGeun Jung, Su Young Moon, Chae Young Park, Hoon moh Seong
Abstract: The present invention relates to a water degradable film comprising hyaluronic acid or a salt thereof and polyphenol compounds. The film of the present invention can transcribe nanofilms in the form of CNT (carbon nanotube), graphene and magnetic particles to various places. The film of the present invention can be dissolved by an aqueous solution or body fluid, and can be effectively used in the medical field since it is non-toxic and biocompatible. The film of the present invention can also be effectively used as a transcript that does not degrade the quality and performance of the device because no residue remains in the electronic device and the existing photolithography process.
Type:
Grant
Filed:
July 21, 2020
Date of Patent:
December 5, 2023
Assignee:
Korea Research Institute of Chemical Technology
Inventors:
Jae-Hyeok Lee, Sun-Hyun Park, Ki-Suk Kim
Abstract: There is provided a dehydrogenation catalyst for producing olefins from alkane gases, in which a metal active component is supported on an alumina carrier containing boron. There is provided a method for preparing a dehydrogenation catalyst for producing olefins from alkane gases. The method includes impregnating alumina in a boron-containing solution and calcining it to provide a boron-alumina carrier; providing a solution containing the metal active component; impregnating the boron-alumina solution in the solution containing the metal active component and drying it; and calcining the boron-alumina carrier on which the metal active component is supported at 700° C. to 900° C.
Type:
Application
Filed:
November 1, 2021
Publication date:
November 30, 2023
Applicants:
SK GAS CO., LTD., KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Inventors:
Daesung PARK, Hawon PARK, Changyeol SONG, Yong Ki PARK, Won Choon CHOI, Ung Gi HONG, Deuk Soo PARK, Miyoung LEE, Hae Bin SHIN, Sanghyeon PARK
Abstract: The present invention provides a complex of LNA probe and graphene oxide, and a nucleic acid detection method using the same. In the present invention, LNA-containing molecular beacon is conjugated through covalent bonding with graphene oxide, a single strand of the molecular beacon binds to a target nucleic acid to form a complex, and the complex is separated from graphene oxide to induce a fluorescence signal. The molecular beacon and graphene oxide can be covalently bonded to minimize non-specific signals, and a LNA-added molecular beacon is designed in a double strand to detect a very low concentration of target nucleic acid with high sensitivity, as well as a fluorescent signal, and the multiple target nucleic acids can be detected simultaneously through diversification of the fluorescent signal to enable easy and accurate detection of a nucleic acid biomarker whose specific expression level is specifically changed according to diseases and disease progression.
Type:
Grant
Filed:
August 30, 2020
Date of Patent:
November 14, 2023
Assignee:
Korea Research Institute of Chemical Technology
Inventors:
Jieon Lee, Woo-keun Kim, Seokjoo Yoon, Bomi Shin