Abstract: The present invention relates to various compounds capable of temporarily hardening soft tissue for surgical suturing of the soft tissue. The compounds according to the present invention can temporarily increase the hardness or tension of soft tissue, thereby improving the suturing efficiency during suturing of the soft tissue, thereby preventing aftereffects or the like from occurring due to insufficient anastomosis. In addition, the compounds according to the present invention can temporarily increase the hardness or tension of soft tissue, particularly pancreas, thereby increasing the suturing efficiency during pancreaticoduodenectomy and effectively preventing pancreatic leakage.

Abstract: Disclosed is an olefin production method which includes: (a) providing the regenerated catalyst and the hydrocarbon including not less than 90 wt % of LPG into Riser of Fast Fluidization Regime, and dehydrogenating in the presence of an alumina type catalyst; (b) separating an effluent from the dehydrogenation reaction into the catalyst and propylene mixture; (c) stripping to remove the hydrocarbon compound included in the catalyst separated at stage (b); (d) mixing the catalyst stripped at stage (c) with the gas including oxygen, and continuously regenerating it; (e) recycling the catalyst regenerated at stage (d) to stage (a), and providing it again into Riser; and (f) producing propylene product by cooling, compressing and separating propylene mixture of the reaction product separated at stage (b).

Abstract: The present invention relates to an inhalation toxicity testing chamber device for nanoparticles having a plurality of concentrations. The present invention provides an inhalation toxicity testing chamber device for nanoparticles having a plurality of concentrations, which: can supply nanoparticles having different concentrations to particle exposure modules by stacking a plurality of particle exposure modules inside a single chamber housing and by allowing each particle exposure module so as to form an independent space from each other; can perform inhalation toxicity testing of nanoparticles having a plurality of concentrations through a single chamber housing by being capable of exposing the test animals put into each particle exposure module to nanoparticles having different concentrations; can easily perform inhalation toxicity tests of nanoparticles in a small scale laboratory etc.

Abstract: The present invention relates to a diagnostic kit for sepsis, comprising: a first core gold nanoparticle having a target capture oligonucleotide coupled thereto, the target capture oligonucleotide binding complementarily to a portion of a sepsis pathogen-specific genome; and a second core gold nanoparticle to which a target capture oligonucleotide having a Raman-active molecule coupled to one end thereof is coupled via the other end thereof, the target capture oligonucleotide including a sequence complementary to a portion of the sepsis pathogen-specific genome which does not overlap with, but is successive to the portion for the first gold nanoparticle, and a method for diagnosis of sepsis, using the same.

Abstract: The present invention relates to a method for effectively recovering a sugar solution containing glucose and saccharogenic residues after saccharification using an acid or a saccharification enzyme of a wood-based or algae biomass, and a device for implementing the method. More specifically, the present invention relates to a method capable of recovering a sugar solution using minimal equipment and water after aggregating fine particles by adding a protein suspension to a suspension of glucose and saccharogenic residues which are produced by saccharifying cellulose by adding an acid or saccharification enzyme to the biomass, while capable of minimizing an amount of saccharide lost in the residues, and a device for implementing the method.

Abstract: Provided is an oxime ester phenylcarbazole compound useful as a photoinitiator for photocrosslinking. Specifically, the carbon atom forming a double bond with the nitrogen atom in the oxime ester moiety of the oxime ester phenylcarbazole compound is bonded to the phenylcarbazole group and is directly bonded to a (C1-C20)alkyl or (C6-C20)aryl group. Also provided is a photopolymerizable composition including the oxime ester phenylcarbazole compound. The oxime ester phenylcarbazole compound and the photopolymerizable composition have improved solubilities, are highly photosensitive, and exhibit excellent physical properties in terms of residual film ratio, pattern stability, resist adhesiveness. Due to these advantages, the oxime ester phenylcarbazole compound and the photopolymerizable composition are suitable for use in black resists, color resists, overcoats, column spacers, and organic insulating films of LCDs.

Abstract: The present invention relates to a method for preparing a four-coordinated organic boron compound, and more specifically, to a method for preparing various and widespread four-coordinated organic boron compounds by directly using an aryl, heteroaryl, or vinyl-functional boronic acid, boroxine, or borate compound as a starting material and adding the compound to any bidentate N,O-ligand, O,O-ligand, or N,N-ligand.

Abstract: A microfabricated platform for mimicking the liver zonation and an evaluating method of zone-specific hepatotoxicity using the same is provided. The microfabricated platform for mimicking the liver zonation prepared according to the method of the present invention is divided into three zones of zone 1, zone 2 and zone 3 similarly to in vivo liver tissue and thus the zone-specific hepatotoxicity of a drug in the liver can be evaluated using the same. According to the present invention, the zone-specific hepatotoxicity results can be analyzed quantitatively by using image analysis, so that the platform of the present invention can be effectively used for in vitro screening of zone-specific hepatotoxicity.

Abstract: The present invention relates to a pharmaceutical composition comprising a DUSP1 inhibitor. The pharmaceutical composition comprising the DUSP1 inhibitor according to the present invention can solve the problems of inhibitors that target the active site because it inhibits DUSP1 by an allosteric inhibitory mechanism, and is effective for preventing or treating diseases involving DUSP1 enzymes, for example, a cancer such as a liver cancer, a breast cancer and a pancreatic cancer, a hepatitis C, and a depression. In particular, the DUSP1 inhibitor according to the present invention is very effective in treating a depression because it directly acts on neuronal growth.

Abstract: The present invention relates to compounds represented by Formula 1 or a pharmaceutically acceptable salt thereof, wherein: R1 is chloro or methyl; R2 is hydrogen or chloro; R3 is hydrogen, fluoro, chloro, bromo, methyl, ethyl, isopropyl, pentyl, hexyl, octyl, methoxy, phenoxy, (4-nitrophenyl)sulfonyl, piperidin-4-yl, or piperazin-1-yl; R4 is hydrogen, chloro, methyl or trifluoromethyl, phenoxy, (4-nitrophenyl)sulfonyl or piperidin-4-yl; or R3 and R4, together with the carbons to which they are attached, form a fused ring selected form the group consisting of: n is 1 or 2. These compounds according to the present invention remarkably inhibits activity of DRAK that inhibits signal systems of TGF-?, which is known to suppress cancer growth, and thus the novel pyrimidine compounds can be used as a pharmaceutical composition for preventing or treating cancer and can be used as a pharmaceutical composition for preventing or treating inflammatory disease.

Abstract: An exhaust gas post processing apparatus of a gasoline vehicle may include a housing mounted on the exhaust pipe to receive the exhaust gas discharged from the engine and to exhaust the exhaust gas passed through rearward thereof, a front end honeycomb catalyst unit embedded in the housing to primarily purify the exhaust gas introduced into the housing through a front end portion of the housing, and a rear end honeycomb catalyst unit embedded in the housing to secondarily purify the exhaust gas via the front end honeycomb catalyst unit before flowing out to a rear end portion of the housing, wherein the front end honeycomb catalyst unit includes a powder type catalyst in which an iridium-ruthenium alloy is supported on an aluminum oxide support powder, and the rear end honeycomb catalyst unit includes three-way catalyst powder which is configured to remove carbon monoxide, nitrogen oxides, and hydrocarbons simultaneously.

Abstract: The present invention relates to a method for converting heavy oil by means of high dispersion of asphaltenes, comprising the steps of: preparing a mixture by mixing an amphiphilic additive and the heavy oil; and performing a hydrogenation reaction on the mixture, wherein the amphiphilic additive comprises both a polar group and a nonpolar group.

Abstract: Provided is a secondary battery having a battery case which accommodates an electrode assembly including a cathode, a anode, and a separator disposed between the cathode and the anode, together with an electrolyte, wherein one or more selected from the group consisting of the cathode, the anode, the separator, the electrolyte, and the interior of the battery case include, as a water adsorbent, a first organic-inorganic hybrid nanoporous material which may be regenerated by desorbing 70% or more of a total adsorption amount of adsorbed water at 150° C. or lower; and optionally, a second organic-inorganic hybrid nanoporous material, of which water adsorption capacity is higher than water desorption capacity at a relative humidity p/p0 of 0.3 or less (herein, p0 represents a saturated vapor pressure at an application temperature and p represents a vapor pressure upon adsorption).

Abstract: The present invention relates to a fatty liver and liver fibrosis evaluation system based on impedance. The fatty liver and liver fibrosis evaluation system based on impedance provided in one aspect of the present invention uses 3-dimensional liver microtissues so that the fatty liver formation and the stiffness changes resulted from liver fibrosis induced by a test drug can be analyzed with non-invasive and highly reproducible manner.

Abstract: A catalyst regenerator includes: a container including a catalyst inlet through which a coked catalyst is introduced and a catalyst outlet to which a regenerated catalyst is discharged; a first supply unit formed below the catalyst inlet and supplying a syngas containing solid carbon to the coked catalyst introduced into the container; and a second supply unit formed below the first supply unit and supplying high-temperature air into the container.

Abstract: The present invention relates to a method for preparing, from wood-based biomass, a high concentration of fermentable sugar which can be effectively used in culturing various industrial fermented bacteria. According to the method of the present invention, biomass can be extracted by hot water prior to a pre-treatment so as to remove extractible substances such as mineral salts to thus minimize the content of impurities in raw materials for an enzymatic saccharification. The biomass from which substances extractible by hot water are removed is pre-treated in the condition where xylan yield rate is maximized, thus achieving maximum inhibition of the generation of over-decomposed products of sugar.

Abstract: The present invention relates to a pharmaceutical composition the prevention or treatment of DYRK-related diseases containing a pyridine-based compound as an active ingredient, a pyridine-based compound of the present invention which is used as an active ingredient of the pharmaceutical composition inhibits the activity of DYRK1A with very high efficacy and selectivity, thereby can be used effectively in the prevention or treatment of DYRK-related diseases, such as Down syndrome, degenerative brain diseases, cancer, and metabolic diseases.

Abstract: Disclosed are a catalyst for producing olefin and a preparation method thereof. The catalyst for producing olefin includes: a support including an alumina and a sub-support component; and a catalytic component comprising a metal component and an alkali metal impregnated on the support. The preparation method includes: providing a support comprising a sub-support component and an alumina; preparing pre-catalyst by dipping a metal component oxide in the support and calcining it; and dipping a metal component oxide and an alkali metal oxide in the pre-catalyst and calcining it.

Abstract: The present invention relates to a pyrimidine derivative compound, an optical isomer thereof, or a pharmaceutically acceptable salt thereof, and a composition for preventing or treating cancer comprising the same as an active ingredient. The pyrimidine derivative compound, the optical isomer thereof, or the pharmaceutically acceptable salt thereof according to the present invention has an excellent selective inhibitory effect especially against TYRO 3 among TAM receptor inhibitory effects, and thus can be used as an excellent composition of preventing or treating cancer without adverse effects resulting from the inhibition of Axl and Mer.

Abstract: The present invention relates to a Ru—Pd bimetallic catalyst for use in hydrogenation of a compound, and more particularly to a catalyst prepared by loading both ruthenium and palladium on a g-C3N4 support and to a selective hydrogenation process of a pyridine group in a reaction system containing both a pyridine group and a benzene group using the catalyst.