Patents Assigned to Korea University Industry and Academy Cooperation Foundation
  • Patent number: 11911519
    Abstract: A device for producing nanoparticles includes: a first connector comprising a first supply tube fitting member, a second supply tube fitting member, and a first discharge tube fitting member; a first tube having one side connected to the first supply tube fitting member; a second tube having one side connected to the second supply tube fitting member; a first conduit having one side connected to the first discharge tube fitting member; a first supply connected to another side of the first tube to supply a first material to the first conduit; and a second supply connected to another side of the second tube to supply a second material to the first conduit.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: February 27, 2024
    Assignees: SOONCHUNHYANG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION, KOREA INSTITUTE OF CERAMIC ENGINEERING AND TECHNOLOGY
    Inventors: Jong Min Lim, Daekyung Sung, Won II Choi, Hyeon Woo Han, Sehee Jeong, Yoonhee Na, Jiseob Woo
  • Patent number: 8501488
    Abstract: The present invention relates to a compound for N-terminal substitution of polypeptides which is used in sequencing and quantifying amino acids and a method for sequencing and quantifying an amino acid sequence using the same. The method for sequencing and quantifying amino acids in accordance with the present invention leads to a relative quantitative analysis of proteins with very high reliability, and can distinctively discriminate between y-type ions and b-type ions on the MS/MS spectra, providing the means for realization of high-reliability protein identification.
    Type: Grant
    Filed: June 29, 2005
    Date of Patent: August 6, 2013
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Sang-Won Lee, Yong-Ho Lee
  • Patent number: 8230754
    Abstract: The present invention provides a safety unit comprising: a case; a rotary linkage disposed at one end thereof at the outside of the case and rotatably mounted at the other end thereof to the case; a force transfer shaft mounted to one side of the rotary linkage in such a fashion as to be oriented perpendicular to the rotating plane of the rotary linkage; a crank linkage rotatably mounted at one end thereof to the inner side of the case and adapted to abut against the force transfer shaft at the outer circumferential edge thereof so as to be transferred with an external force to be rotatably moved; and a support means rotatably connected to the other end of the crank linkage and adapted to allow for the rotation of the crank linkage when an external force having a value larger than a predetermined threshold value is exerted to the rotary linkage.
    Type: Grant
    Filed: August 11, 2006
    Date of Patent: July 31, 2012
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Jae-Bok Song, Jung-Jun Park, Byeong-Sang Kim
  • Publication number: 20120083002
    Abstract: The present invention relates to a composition for modulating the activation of Nurr1, the composition comprising an agonist or an antagonist of a dopamine D2 receptor, methods for modulating the activation of Nurr1 by the dopamine D2 receptor, a method and composition for treating Nurr1-related diseases using the dopamine D2 receptor, and methods for screening a modulator of a dopamine D2 receptor of a test compound. Accordingly, the activation of Nurr1 can be modulated by treating the dopaminergic neurons with the agonist or the antagonist of the dopamine D2 receptor, thereby enhancing or inhibiting generation of the dopaminergic neurons.
    Type: Application
    Filed: October 12, 2011
    Publication date: April 5, 2012
    Applicant: Korea University Industry And Academy Cooperation Foundation
    Inventors: Ja hyun BAIK, Sung yul KIM
  • Patent number: 8084647
    Abstract: A two-photon probe for real-time monitoring of intracellular calcium ions is provided. The two-photon probe is very suitable for real-time imaging of intracellular calcium ions, shows 20˜50-fold TPEF enhancement in response to Ca2+, has a dissociation constant (KdTP) of 0.14±0.02 to 0.25±0.03 ?M, and emits 5-fold stronger TPEF than currently available one-photon fluorescent Ca2+ probes. Unlike the previously available probes, the two-photon probe can selectively detect dynamic levels of intracellular free Ca2+ in live cells and living tissues without interference from other metal ions and from the membrane-bound probes. Moreover, the two-photon probe is capable of monitoring the calcium waves at a depth of 100-300 ?m in live tissues for 1,100-4,000 s using two-photon microscopy (TPM) with no artifacts of photo-bleaching. Further provided are a method for preparing the two-photon probe and a method for real-time monitoring of intracellular calcium ions using the two-photon probe.
    Type: Grant
    Filed: January 21, 2008
    Date of Patent: December 27, 2011
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Bong-Rae Cho, Hwan Myung Kim
  • Patent number: 8023835
    Abstract: An optical receiver with a threshold voltage convergence and audio apparatus and communication apparatus using the optical receiver are provided. The optical receiver of the present invention includes an optical detector for converting a received optical signal to a current signal; a transimpedance amplifier for converting the current signal to a voltage signal; a level shifter for converging the voltage signal to a threshold voltage by removing an offset of the voltage signal, the level shifter comprising a plurality of linear subtractors connected in series; a reference voltage generator for generating a reference voltage in proportion to a variation of the offset of the voltage signal; and a comparator for comparing the threshold voltage and the reference voltage and generating a digital signal of a logic level according to a comparison result.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: September 20, 2011
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Gil Su Kim, Soo Won Kim
  • Patent number: 7960130
    Abstract: The present invention relates to a method for activation of TRPA1 (transient receptor potential cation channel, subfamily A, member 1) using acetaldehyde, more precisely a method for selecting a candidate for TRPA1 activation blocker from neurons activated by acetaldehyde. Acetaldehyde of the present invention works on TRPA1 specifically so that it facilitates the isolation of sensory neurons expressing TRPA1. Therefore, acetaldehyde of the invention can be effectively used for the studies on TRPA1 mechanisms and the development of a TRPA1 based anodyne.
    Type: Grant
    Filed: April 24, 2008
    Date of Patent: June 14, 2011
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Sun Wook Hwang, Sang Su Bang
  • Patent number: 7935394
    Abstract: Disclosed herein is a polar nematic liquid crystal assembly. The liquid crystal assembly comprises 5˜7.5% by weight of a dopant having the structure of Formula 1 below: (wherein X is an alkyl, alkenyl or heteroalkyl group having three or more carbon atoms) and 92.5˜95% by weight of smectic liquid crystal molecules having a linear alkyl chain wherein the N-bonding moiety of the dopant is spontaneously bonded to the alkyl chain of the smectic liquid crystal molecules to induce macroscopic spontaneous polarization in a particular direction.
    Type: Grant
    Filed: November 9, 2005
    Date of Patent: May 3, 2011
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Tong-Kun Lim, Ji-Hoon Lee
  • Patent number: 7915397
    Abstract: The present invention relates to a promoter of hot pepper related to TMV-resistance, more precisely a promoter of the gene related to TMV-resistance and a method for regulating the expression of a target protein by using a transcription factor binding to the same. The method of the present invention can be effectively used for the regulation of the expression of a target protein in disease-resistant plants.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: March 29, 2011
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Kyung-Hee Paek, Boo-Ja Lee, Ki-Jeong Kim, Soo Bok Choi
  • Patent number: 7888532
    Abstract: A two-photon probe for real-time monitoring of intracellular magnesium ions is provided. Specifically, the two-photon probe is represented by Formula 1: wherein R is H or CH2OCOCH3. The two-photon probe is very suitable for real-time imaging of intracellular magnesium ions. The two-photon probe shows 17-fold two-photon excited fluorescence enhancement in response to Mg2+, which is 7-fold stronger than commercial probes, thus enabling staining of cells in a greatly reduced amount. In addition, the two-photon probe has a sufficiently low molecular weight to stain cells and is very suitable for monitoring Mg2+ ions present in the deep tissue. Furthermore, the two-photon probe can be effectively used for the quantitative as well as qualitative detection of intracellular magnesium ions. Further provided are a method for preparing the two-photon probe and a method for real-time monitoring of intracellular magnesium ions using the two-photon probe.
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: February 15, 2011
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventor: Bong-Rae Cho
  • Patent number: 7875320
    Abstract: A method for producing a film of vanadium pentoxide nanowires having improved alignment is provided.
    Type: Grant
    Filed: February 12, 2008
    Date of Patent: January 25, 2011
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Jae-Hyun Park, Jeong-Sook Ha, Yong-Kwan Kim
  • Publication number: 20100316792
    Abstract: A method of fabricating an electron emission source and a method of fabricating an electronic device by using the method. An electron emission material layer of the electron emission source is formed by filtration and transfer, and a mask including windows (openings) having predetermined patterns is used in a transfer process so that an electron emission layer having a desired shape may be freely obtained.
    Type: Application
    Filed: January 12, 2010
    Publication date: December 16, 2010
    Applicant: KOREA UNIVERSITY INDUSTRY AND ACADEMY COOPERATION FOUNDATION
    Inventors: Cheol Jin Lee, Seung Il Jung, Dong Hoon Shin
  • Patent number: 7830184
    Abstract: A frequency multiplier is disclosed. A plurality of voltage regulators each regulate levels of voltages at first and second common nodes in response to a corresponding one of input signals from a voltage-controlled delay line. An input buffer charges the first node or discharges the second node in response to a feedback signal. An output buffer regulates a level of a voltage at an output node and outputs a frequency-multiplied clock signal and the feedback signal corresponding to the voltage level of the output node. A discharge circuit discharges the first node before a rising edge of each of the input signals from the voltage-controlled delay line is inputted. A charge circuit charges the second node before the rising edge of each of the input signals from the voltage-controlled delay line is inputted.
    Type: Grant
    Filed: July 27, 2005
    Date of Patent: November 9, 2010
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Chul-Woo Kim, Jin-Han Kim, Seok-Ryung Yoon, Young-Ho Kwak, Seok-Soo Yoon
  • Patent number: 7814333
    Abstract: Methods and apparatuses for detecting and recovering from a buffer overflow attack are provided. A method of recovering an operation state of a processor from a buffer overflow attach includes: detecting whether a buffer overflow attack is made on any write operation while storing write operations that are potential targets of buffer overflow attacks in a predetermined location instead of an original destination to store write operations; storing the contents stored in the predetermined location at a predetermined interval in the original destination for storing write operations if no buffer overflow attack is detected and discarding unsafe write operations subsequent to a buffer overflow attack if a buffer overflow attack is detected; and ignoring the unsafe write operations subsequent to the buffer overflow attack if a buffer overflow attack is detected.
    Type: Grant
    Filed: March 18, 2005
    Date of Patent: October 12, 2010
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Lynn Choi, Yong Shin
  • Patent number: 7781644
    Abstract: Disclosed herein are an Arabidopsis gene (AtLEJ1), acting as an inhibitor of the biosynthesis of the phytohormones jasmonic acid and ethylene, and a method for producing a male sterile transgenic plant using the same. The gene guarantees stable male sterile strains which need no maintainers for the maintenance thereof. Also, the transgenic plants comprising the gene can be readily restored to a fertile phenotype merely through hormonal treatment. Although the preferred embodiments of the present invention have been disclosed for illustrative purposes, those skilled in the art will appreciate that various modifications, additions and substitutions are possible, without departing from the scope and spirit of the invention as disclosed in the accompanying claims.
    Type: Grant
    Filed: April 3, 2007
    Date of Patent: August 24, 2010
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Jeong Sheop Shin, Kwang Wook Jung, Kyoung Shin Yoo, Mei Hua Cui, Yun Young Kim, Sung Han Ok
  • Patent number: 7662084
    Abstract: A blood pump actuator to generate a driving force for driving a blood pump is disclosed. The blood pump actuator includes: a motor unit having a stator and a rotor, and rotating to generate a rotating force; a cam unit to convert the rotating motion of the motor unit into a rectilinear reciprocating motion; and a bellows unit having a bellows, which is expandable and contractible and contains a fluid therein, and an upper bellows plate and a lower bellows plate respectively attached to the upper and lower ends of the bellows, wherein the lower bellows plate moves upwards and downwards in a vertical direction according to the rectilinear reciprocating motion of the cam unit engaging with the lower bellows plate, and the bellows repeatedly expands and contracts according to the vertical movement of the lower bellows plate.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: February 16, 2010
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Kyung Sun, Kyu Back Lee, Yong Doo Park, Ho Sung Son, Chang Mo Hwang, Gi Seok Jeong
  • Patent number: 7637147
    Abstract: An ultrahigh-pressure dual on-line solid phase extraction/capillary reverse-phase liquid chromatography (DO-SPE/cRPLC) system is provided.
    Type: Grant
    Filed: November 1, 2007
    Date of Patent: December 29, 2009
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Sang Won Lee, Seok Won Hyung
  • Publication number: 20090269280
    Abstract: The present invention relates to a method for activation of TRPA1 (transient receptor potential cation channel, subfamily A, member 1) using acetaldehyde, more precisely a method for selecting a candidate for TRPA1 activation blocker from neurons activated by acetaldehyde. Acetaldehyde of the present invention works on TRPA1 specifically so that it facilitates the isolation of sensory neurons expressing TRPA1. Therefore, acetaldehyde of the invention can be effectively used for the studies on TRPA1 mechanisms and the development of a TRPA1 based anodyne.
    Type: Application
    Filed: April 24, 2008
    Publication date: October 29, 2009
    Applicant: Korea University Industry and Academy Cooperation Foundation
    Inventors: Sun Wook Hwang, Sang Su Bang
  • Patent number: 7592387
    Abstract: A clay-polyurethane nanocomposite comprising a clay and a polyurethane covalently bonded to the surface of the clay wherein the polyurethane is formed by reacting a clay-containing diisocyanate compound with a polyol, the clay-containing diisocyanate compound contains a diisocyanate compound covalently bonded to surface silanol groups of the clay and 0.5˜5% by weight of the clay based on the diisocyanate compound, and the clay is exfoliated by the polyurethane such that no wide-angle X-ray diffraction (WAXD) peak is detected between 2° and 10° by XRD measurement. The clay-polyurethane nanocomposite structure has clay layers are completely exfoliated. In addition, the clay-polyurethane nanocomposite can be foamed to prepare a foamed clay-polyurethane nanocomposite.
    Type: Grant
    Filed: January 7, 2005
    Date of Patent: September 22, 2009
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Woo-Nyon Kim, Won-Jin Seo, Jae-Sung Han
  • Patent number: 7538210
    Abstract: Disclosed herein are a novel sucrose-inducible promoter sequence and a 5? untranslated region which are derived from sweetpotato ADP-glucose pyrophosphorlyase gene (ibAGP1) (SEQ ID NO: 1). Also disclosed are expression vectors using the same sequences and a transgenic plant using the same vectors. The promoter and 5? untranslated region according to the present invention can confer a high level of sucrose-inducible expression in plants, particularly in plant storage roots which contain sucrose in relatively large quantities to accumulate starch in large quantities in plants. Therefore the present invention may be useful for the generation of transgenic plants to produce useful proteins in large quantities in plant storage roots.
    Type: Grant
    Filed: August 25, 2005
    Date of Patent: May 26, 2009
    Assignee: Korea University Industry and Academy Cooperation Foundation
    Inventors: Jung Myung Bae, Man Sup Kwak, Seol Ah Noh, Jeong Sheop Shin, Shin Woo Lee