Abstract: The present disclosure provides compounds and pharmaceutically acceptable salt thereof, and methods of using the same. The compounds and methods have a range of utilities as therapeutics, diagnostics, and research tools. In particular, the subject compositions and methods are useful for reducing signaling output of oncogenic proteins.
Type:
Grant
Filed:
June 2, 2023
Date of Patent:
February 27, 2024
Assignee:
KUMQUAT BIOSCIENCES INC.
Inventors:
Baogen Wu, Pingda Ren, Zhiyong Chen, Yi Liu
Abstract: The present disclosure provides compounds represented by Formula (I-1): and pharmaceutically acceptable salts thereof, and methods of using the same. The compounds and methods have a range of utilities as therapeutics, diagnostics, and research tools. In particular, the subject compositions and methods are useful for reducing signaling output of oncogenic proteins.
Type:
Grant
Filed:
March 2, 2022
Date of Patent:
May 16, 2023
Assignee:
Kumquat Biosciences Inc.
Inventors:
Baogen Wu, Xiangzhu Wang, Xiaoming Li, Zhiyong Chen, Pingda Ren, Yi Liu