Patents Assigned to Kyoritsu Seiyaku Corporation
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Patent number: 9987359Abstract: The present invention provides a subcutaneous injection product for cattle for inducing superovulation characterized by comprising aluminum hydroxide gel and an efficient amount of a gonadotropin, wherein the concentration of the aluminum hydroxide is, in terms of the amount of aluminum, higher than or equal to 0.2 mg/mL and lower than 1.0 mg/mL, which is a subcutaneous injection product that is useful for producing good calves and that can induce superovulation in a cow by a single administration. The present invention also provides a method for producing good calves undergoing steps of subcutaneously injecting the aforementioned injection product into a cow to thereby induce superovulation, inducing estrus in the cow, conducting artificial insemination, and then collecting fertilized eggs.Type: GrantFiled: May 23, 2014Date of Patent: June 5, 2018Assignee: Kyoritsu Seiyaku CorporationInventors: Koji Kimura, Shuichi Matsuyama, Kenyo Ishii, Makoto Seki, Toshiya Hamada
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Publication number: 20160250333Abstract: The present invention provides a subcutaneous injection product for cattle for inducing superovulation characterized by comprising aluminum hydroxide gel and an efficient amount of a gonadotropin, wherein the concentration of the aluminum hydroxide is, in terms of the amount of aluminum, higher than or equal to 0.2 mg/mL and lower than 1.0 mg/mL, which is a subcutaneous injection product that is useful for producing good calves and that can induce superovulation in a cow by a single administration. The present invention also provides a method for producing good calves undergoing steps of subcutaneously injecting the aforementioned injection product into a cow to thereby induce superovulation, inducing estrus in the cow, conducting artificial insemination, and then collecting fertilized eggs.Type: ApplicationFiled: May 23, 2014Publication date: September 1, 2016Applicant: Kyoritsu Seiyaku CorporationInventors: Koji Kimura, Shuichi Matsuyama, Kenyo Ishii, Makoto Seki, Toshiya Hamada
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Patent number: 9381241Abstract: Problem to be Solved: The present invention provides a novel mucosal adjuvant. Solution: The present invention provides a mucosal adjuvant composition containing at least a composition comprising molecules having a molecular weight in a range of 100 to 300 kDa obtained from cells or culture fluid of Bordetella bronchiseptica. Administration of the mucosal adjuvant composition to a non-human animal at a surface of the mucous membrane can enhance immunity at the surface of mucous membrane. Therefore preventive effects against trans-mucosal infection can be increased by administering an inactivated vaccine against trans-mucosal infection and the mucosal adjuvant composition to a non-human animal at a surface of mucous membrane. The present invention is effective for preventing trans-mucosal infections, including one or more infections of e.g., canine parainfluenza, canine adenovirus, canine coronavirus, canine parvovirus, canine distemper virus, canine herpesvirus, reovirus and pneumovirus.Type: GrantFiled: September 27, 2011Date of Patent: July 5, 2016Assignee: KYORITSU SEIYAKU CORPORATIONInventors: Ken-ichi Asai, Kazuo Kawakami, Masami Mochizuki
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Publication number: 20130302360Abstract: Problem to be Solved: The present invention provides a novel mucosal adjuvant. Solution: The present invention provides a mucosal adjuvant composition containing at least a composition comprising molecules having a molecular weight in a range of 100 to 300 kDa obtained from cells or culture fluid of Bordetella bronchiseptica. Administration of the mucosal adjuvant composition to a non-human animal at a surface of the mucous membrane can enhance immunity at the surface of mucous membrane. Therefore preventive effects against trans-mucosal infection can be increased by administering an inactivated vaccine against trans-mucosal infection and the mucosal adjuvant composition to a non-human animal at a surface of mucous membrane. The present invention is effective for preventing trans-mucosal infections, including one or more infections of e.g., canine parainfluenza, canine adenovirus, canine coronavirus, canine parvovirus, canine distemper virus, canine herpesvirus, reovirus and pneumovirus.Type: ApplicationFiled: September 27, 2011Publication date: November 14, 2013Applicant: KYORITSU SEIYAKU CORPORATIONInventors: Ken-ichi Asai, Kazuo Kawakami, Masami Mochizuki
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Patent number: 8246963Abstract: Disclosed is a vaccine for edwardsiellosis and streptococcosis in a fish. Specifically, disclosed is a vaccine for edwardsiellosis in a fish, which comprises inactivated cells of (A) an Edwardsiella tarda strain derived from the target fish, and inactivated cells of (B) an Edwardsiella tarda strain derived from a fish other than the target fish, wherein, when the strain (A) is a typical Edwardsiella tarda strain, the strain (B) is an atypical Edwardsiella tarda strain, whereas when the strain (A) is an atypical Edwardsiella tarda strain, the strain (B) is a typical Edwardsiella tarda strain. Also specifically disclosed is a vaccine for edwardsiellosis and/or streptococcosis in a fish, which comprises the components mentioned above and inactivated cells of (C) Streptococcus iniae and/or Streptococcus parauberis.Type: GrantFiled: June 5, 2007Date of Patent: August 21, 2012Assignees: Kyoritsu Seiyaku Corporation, Yukinori TakahashiInventors: Yukinori Takahashi, Michinari Abe
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Publication number: 20120151882Abstract: A waste storage device includes a waste storage part for storing a waste item and a packaging device arranged in an upper part of the waste storage part. The packaging device includes two film feed rollers, two waste sealing rollers which pull out films and are arranged in parallel that the peripheral surfaces thereof are in contact via the pulled out respective films in a normal state and at least one of which has the peripheral surface that is elastically deformed along the shape of the waste item, and a driving part which rotates the rollers. Two friction rollers which are driven and rotated to sandwich the films sealing the waste item having passed between the waste sealing rollers and pull them downward are provided below the waste sealing rollers. The device prevents a waste item sealed with resin films from being caught in rollers such as waste sealing rollers.Type: ApplicationFiled: June 22, 2010Publication date: June 21, 2012Applicant: Kyoritsu Seiyaku CorporationInventor: Yoichi Nakano
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Patent number: 7910366Abstract: The invention relates to a cell strain induced from MDCK cells as dog kidney-derived cells, and being able to be cultured without ingredients derived from animals. The cell strain is produced by adapting a MDCK cell to a medium without a serum but with a cell growth factor; and culturing the cell in a medium with an RPMI 1640 medium and a soybean-derived peptone but without ingredients derived from animals.Type: GrantFiled: March 10, 2005Date of Patent: March 22, 2011Assignee: Kyoritsu Seiyaku CorporationInventor: Masami Mochizuki
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Patent number: 7767451Abstract: The present invention provides a cell strain which is derived from an fcwf-4 cell that is a cell derived from a feline whole fetus and which is capable of being cultured without animal-derived proteins, a method for producing the cell strain, and a method for producing a virus by using the cell. An inexpensive and safe feline vaccine can be produced according to the present invention.Type: GrantFiled: April 28, 2006Date of Patent: August 3, 2010Assignee: Kyoritsu Seiyaku CorporationInventor: Masami Mochizuki
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Patent number: 7659114Abstract: An attenuated feline recombinant herpesvirus 1 (FHV-1), which is prepared by identifying gene regions in the genome wherein inserted foreign genes can be expressed without affecting the replication of FHV-1 and has least two types of foreign nucleic acid sequences inserted thereinto, usable as a vector virus or a vaccine. In this attenuated recombinant FHV-1, at least two types of foreign genes are inserted in such a manner as allowing the expression into two different gene regions exerting no lethal effect on the proliferation of the virus in the feline herpesvirus 1 genome.Type: GrantFiled: October 10, 2007Date of Patent: February 9, 2010Assignee: Kyoritsu Seiyaku CorporationInventors: Kazuo Kawakami, Masahiko Kishi, Masami Mochizuki
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Publication number: 20090098159Abstract: The present invention provides a cell strain which is derived from an fcwf-4 cell that is a cell derived from a feline whole fetus and which is capable of being cultured without animal-derived proteins, a method for producing the cell strain, and a method for producing a virus by using the cell. An inexpensive and safe feline vaccine can be produced according to the present invention.Type: ApplicationFiled: April 28, 2006Publication date: April 16, 2009Applicant: Kyoritsu Seiyaku CorporationInventor: Masami Mochizuki
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Publication number: 20080152670Abstract: An attenuated feline recombinant herpesvirus 1 (FHV-1), which is prepared by identifying gene regions in the genome wherein inserted foreign genes can be expressed without affecting the replication of FHV-1 and has least two types of foreign nucleic acid sequences inserted thereinto, usable as a vector virus or a vaccine. In this attenuated recombinant FHV-1, at least two types of foreign genes are inserted in such a manner as allowing the expression into two different gene regions exerting no lethal effect on the proliferation of the virus in the feline herpesvirus 1 genome.Type: ApplicationFiled: October 10, 2007Publication date: June 26, 2008Applicant: Kyoritsu Seiyaku CorporationInventors: Kazuo Kawakami, Masahiko Kishi, Masami Mochizuki
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Patent number: 7297533Abstract: An attenuated feline recombinant herpesvirus 1 (FHV-1), which is prepared by identifying gene regions in the genome wherein inserted foreign genes can be expressed without affecting the replication of FHV-1 and has least two types of foreign nucleic acid sequences inserted thereinto, usable as a vector virus or a vaccine. In this attenuated recombinant FHV-1, at least two types of foreign genes are inserted in such a manner as allowing the expression into two different gene regions exerting no lethal effect on the proliferation of the virus in the feline herpesvirus 1 genome.Type: GrantFiled: October 5, 2001Date of Patent: November 20, 2007Assignee: Kyoritsu Seiyaku CorporationInventors: Kazuo Kawakami, Masahiko Kishi, Masami Mochizuki
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Patent number: 7235528Abstract: The invention provides an immunostimulant for a lactating bovine mammary gland, said immunostimulant containing lactoferrin or pharmaceutically acceptable salt thereof as an active ingredient.Type: GrantFiled: June 24, 2002Date of Patent: June 26, 2007Assignee: Kyoritsu Seiyaku CorporationInventors: Katsuo Kumagai, Ken-ichi Komine, Kenzo Kai
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Publication number: 20060283153Abstract: The present invention automatically and continuously packs women's sanitary products, paper diapers, and the like in a sealed manner and is installed in toilets of hotels, public toilets, and the like used by general public. When a trash is put in, film pull-out rollers (50), (60) are rotated by a motor (70) and films (31), (41) are pulled out from film feed rollers (30), (40). When passing between film pull-out rollers (50), (60), the trash is sealingly packed between the two films (31), (41). Therefore, since the trash can be automatically packed in a sealed manner and a clean state is maintained, the present invention is suitable for installation in toilets of hotels, public toilets, and the like used by general public.Type: ApplicationFiled: October 14, 2004Publication date: December 21, 2006Applicant: KYORITSU SEIYAKU CORPORATIONInventor: Yoichi Nakano
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Patent number: 6872709Abstract: The present invention provides a therapeutic agent and therapeutic method for treatment of mastitis in livestock comprising glycyrrhizin and pharmaceutically acceptable salts thereof as effective ingredients.Type: GrantFiled: July 28, 2003Date of Patent: March 29, 2005Assignee: Kyoritsu Seiyaku CorporationInventors: Katsuo Kumagai, Kenzo Kai, Ken-ichi Komine