Abstract: Method for preparing a factor VIII solution that is essentially free of viruses and essentially devoid of vWF (von Willebrand factor) and factor VIII-vWF complexes by (a) obtaining a starting factor VIII solution devoid of factor VIII-vWF complexes; and (b) filtering the solution through a hydrophilic virus filter.
Type:
Grant
Filed:
December 14, 1998
Date of Patent:
November 22, 2005
Assignee:
Laboratoire Francias du Franctionnement et des Biotechnologies
Inventors:
Abdessatar Chtourou, Michel Nogre, Pierre Porte