Abstract: A pharmaceutical composition useful for treating hypogonadism is disclosed. The composition comprises an androgenic or anabolic steroid, a C1-C4 alcohol, a penetration enhancer such as isopropyl myristate, and water. Also disclosed is a method for treating hypogonadism utilizing the composition.
Abstract: The invention relates to derivatives of general formula I ##STR1## The invention also relates to pharmaceutical and cosmetic compositions comprising derivatives of general formula I.
Abstract: The present invention provides .beta.-carboline derivatives useful as components of cosmetic, medicinal, and pharmaceutical compositions. The medicinal and pharmaceutical compositions can be used to induce hypnotic activity in a subject. Methods of producing the .beta.-carboline derivatives are provided as well.
Type:
Grant
Filed:
March 17, 1998
Date of Patent:
April 11, 2000
Assignees:
Cemaf, Laboratories Besins Iscovesco
Inventors:
J-Bernard Fourtillan, Marianne Fourtillan, Jean-Claude Jacquesy, Marie-Paule Jouannetaud, Bruno Violeau, Omar Karam
Abstract: The present invention relates to spiro?3H-indole-3(2H),3'-pyrrolidine! derivatives of general formula I ##STR1## as defined in the description. The invention also relates to a process for their preparation and to their therapeutic use, in particular for the treatment of complaints associated with melatonin disorders, and to the pharmaceutical and cosmetic compositions comprising them.
Type:
Grant
Filed:
December 11, 1996
Date of Patent:
June 9, 1998
Assignees:
CEMAF, Laboratories Besins Iscovesco
Inventors:
Jean-Bernard Fourtillan, Marianne Fourtillan, Jean-Claude Jacquesy, Marie-Paule Jouannetaud, Bruno Violeau, Omar Karam