Patents Assigned to Laboratories Expanscience
  • Patent number: 9952201
    Abstract: The invention relates to in vitro methods for testing formulations or active ingredients for preventing the harmful effects of UV on children's skin, in particular children aged three or less. The inventors have developed methods for evaluating the in vitro efficacy of formulations in preventing the harmful effects of UV on the skin of children aged three or less, using a skin model specifically capable of reproducing the characteristics of the skin of children of this age.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: April 24, 2018
    Assignee: LABORATORIES EXPANSCIENCE
    Inventors: Caroline Baudouin, Stephanie Bredif, Philippe Msika
  • Patent number: 9023810
    Abstract: The invention relates to the use of a compound comprising D-mannoheptulose and/or perseitol for producing a drug for treating and/or preventing diseases related to the modification of an innate and/or acquired immunity by increasing the production of antimicrobial peptides, preferably hBD-2 without inducing inflammatory reactions, irritation or intolerance. Said compound can also comprise a peptidic avocado extract an/or a peptidic lupin extract.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: May 5, 2015
    Assignee: Laboratories Expanscience
    Inventors: Antoine Piccirilli, Nathalie Piccardi, Philippe Msika, François Paul, Stéphanie Bredif
  • Publication number: 20120294887
    Abstract: The invention relates to a method for the solid/liquid extraction of an oil or butter, particularly having a high unsaponifiable content, contained in at least one solid vegetable matter or a micro-organism. The method includes at least the following steps: solid/liquid extraction of at least one solid vegetable matter or a micro-organism using a first solvent system comprising a concentration of solvent selected from among fluorinated aromatic solvents, particularly trifluorotoluene (BTF) and hexafluorobenzene (BHF), tert-butyl ethers, particularly 2-ethoxy-2-methylpropane, also known as ethyl-tert-butyl-ether (ETBE), and 2-methoxy-2-methylpropane or methyl-tert-butylether (MTBE), solvents comprising at least one silicon atom, particularly hexamethyldisiloxane (HMDS) and tetramethylsilane (TMS), methyl-tetrahydrofuran (MeTHF), and mixtures thereof, representing at least 50 vol.
    Type: Application
    Filed: January 31, 2011
    Publication date: November 22, 2012
    Applicant: LABORATORIES EXPANSCIENCE
    Inventors: Alex Saunois, Jacques Legrand, Eglantine Mercier
  • Patent number: 7883729
    Abstract: The invention concerns a natural vegetable oil selected among palm oil, corn germ oil, sunflower oil and canola oil, concentrated in unsaponifiable matters, such that said oil unsaponifiable matter content is 3 to 15% m/m. Said concentrated natural vegetable oil constitutes a novel food ingredient enriched in particular in vitamin E and phytosterol, useful as favored food source in vitamin E and phytosterol, meeting recommended daily intake.
    Type: Grant
    Filed: March 19, 2001
    Date of Patent: February 8, 2011
    Assignee: Laboratories Expanscience
    Inventors: Carole Kohler, Philippe Msika, Antoine Piccirilli
  • Patent number: 7872043
    Abstract: The invention relates to the use of one or several synthetic or natural furan alkyls for cosmetically treating cellulite. Said furan alkyls preferably correspond to formula (I), wherein identical or different R1, R2, R3et R4 are independently of each other a hydrogen atom, a C1-C35alkyl radical, C1-C35 alcenyl radical or a C1-C35 alcynyl radical, preferably C10-C22, wherein said alkyl, alcenyl and alcynyl radicals are substitutable and R1, R2, R3 are preferably a hydrogen atom.
    Type: Grant
    Filed: May 27, 2005
    Date of Patent: January 18, 2011
    Assignee: Laboratories Expanscience
    Inventors: Antoine Piccirilli, Philippe Msika, Nathalie Piccardi
  • Patent number: 7863472
    Abstract: The present invention concerns a process for producing refined avocado oil rich in triglycerides. The invention also pertains to refined avocado oil rich in triglycerides obtainable by said process. Advantageously, the refined avocado oil of the invention contains a sterols-enriched unsaponifiable fraction. Advantageously, the refined avocado oil of the invention is substantially free of acetogenins and furanic lipids. The invention also concerns compositions containing said oil. The invention also pertains to such compositions for use as a medication, as a dermatological agent, as a cosmetic agent, or as a nutriceutical, for human or animal use.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: January 4, 2011
    Assignee: Laboratories Expanscience
    Inventors: Philippe Msika, Jacques Legrand
  • Patent number: 7763647
    Abstract: The invention relates to compositions intended for external topical use comprising a true solution containing a chromane or chromene derivative having formula (I), preferably a flavonoid, dissolved in a suitable solvent. The invention also relates to a method for preparing such compositions and the use of said compositions as sun protection agents for the skin, advantageously as agents having an anti-erythemal, anti-oxidant, anti-radical, anti-inflammatory or vasculotropic activity.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: July 27, 2010
    Assignee: Laboratories Expanscience
    Inventors: Philippe Msika, Antoine Piccirilli, Nathalie Piccardi, Nicole Broutin
  • Patent number: 7744933
    Abstract: The invention relates to the use of at least one unsaponifiable component of vegetable oil, in particular of avocado, soya bean and/or lupin oils, for the preparation of a medicament intended to stimulate the expression of TGF-? or the expression of the plasminogen activator inhibitor PAI-1. The invention also relates to a method of cosmetic treatment comprising the application of at least one unsaponifiable component of vegetable oil as well as the use of the latter as additive in a food for human beings and/or for animals.
    Type: Grant
    Filed: October 2, 2008
    Date of Patent: June 29, 2010
    Assignee: Laboratories Expanscience
    Inventors: Karim Boumediene, Jean-Pierre Pujol, Georges Bernard Guillou, Philippe Msika, Chafik Ghayor