Patents Assigned to Laboratories, UPSA
  • Method for treatment of pain
    Patent number: 6593331
    Abstract: A method of treating pain with acetaminophen comprises the concurrent administration of a hydroxyazapirone selected from 6-hydroxybuspirone or 3-hydroxygepirone. This combination of agents results in a more morphine-like analgesic response characterized by rapid onset and greater pain relief.
    Type: Grant
    Filed: April 4, 2002
    Date of Patent: July 15, 2003
    Assignees: Laboratories UPSA, Bristol-Myers Squibb Company
    Inventors: Francoise Camborde, Alix Cloarec, Charles Conway
  • Azapirone pain treatment
    Patent number: 6566361
    Abstract: A method of treating pain with acetaminophen comprises the concurrent administration of an azapirone such as buspirone. This combination of agents surprisingly results in a strengthened analgesic response characterized by rapid onset, greater pain relief, and a longer duration of action.
    Type: Grant
    Filed: May 17, 2001
    Date of Patent: May 20, 2003
    Assignees: Laboratories, UPSA, Bristol-Myers Squibb Company
    Inventors: Francoise Camborde, Alix Cloarec, Charles Conway
  • 1,2-diarylmethylene derivatives, their methods of preparation and their uses in therapeutics
    Patent number: 5972950
    Abstract: The present invention relates to the derivatives of formula: ##STR1## and to their use in therapeutics, especially as drugs with anti-inflammatory and analgesic properties.
    Type: Grant
    Filed: October 6, 1997
    Date of Patent: October 26, 1999
    Assignee: Laboratories UPSA
    Inventors: Eric Nicolai, Jean-Marie Teulon
  • 3,4-diaryloxazolone derivatives, their methods of preparation and their uses in therapeutics
    Patent number: 5866596
    Abstract: The present invention relates to the derivatives of formula: ##STR1## and to their use in therapeutics, especially as drugs with anti-inflammatory and analgesic properties.
    Type: Grant
    Filed: March 24, 1997
    Date of Patent: February 2, 1999
    Assignee: Laboratories UPSA
    Inventors: Eric Sartori, Jean-Marie Teulon
  • 3,4-diarylthiazolin-2-one or -2-thione derivatives, their methods of preparation and their uses in their methods of preparation and their uses in therapeutics
    Patent number: 5859036
    Abstract: The present invention relates to derivatives of formula ##STR1## and to their use in therapeutics especially as drugs with anti-inflammatory and analgesic properties.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: January 12, 1999
    Assignee: Laboratories UPSA
    Inventors: Eric Sartori, Jean-Marie Teulon
  • 1,2 diarylmethylene derivatives, their methods of preparation and their uses in therapeutics
    Patent number: 5840753
    Abstract: The present invention relates to the derivatives of formula: ##STR1## and to their use in therapeutics, especially as drugs with anti-inflammatory and analgesic properties.
    Type: Grant
    Filed: March 24, 1997
    Date of Patent: November 24, 1998
    Assignee: Laboratories UPSA
    Inventors: Eric Nicolai, Jean-Marie Teulon
  • Diarylmethylidenefuran derivatives and their uses in therapeutics
    Patent number: 5807873
    Abstract: The present invention relates to the derivatives of the formula ##STR1## and to their use in therapeutics, especially as drugs with anti-inflammatory and analgesic properties.
    Type: Grant
    Filed: March 27, 1997
    Date of Patent: September 15, 1998
    Assignee: Laboratories UPSA
    Inventors: Eric Nicolai, Jean-Marie Teulon
  • 1,2-Diarylindole derivatives, processes for their preparation and their uses in therapeutics
    Patent number: 5723485
    Abstract: The present invention relates to the derivatives of the formula ##STR1## and to their use in therapeutics, especially as drugs with anti-inflammatory and analgesic properties.
    Type: Grant
    Filed: October 7, 1996
    Date of Patent: March 3, 1998
    Assignee: Laboratories UPSA
    Inventors: Timur Gungor, Jean-Marie Teulon
  • Effervescent pharmaceutical composition containing ibuprofen and its method of preparation
    Patent number: 5567437
    Abstract: The present invention relates to a novel pharmaceutical composition for the preparation of effervescent powders or tablets incorporating ibuprofen or one of its pharmaceutically acceptable salts as the active ingredient. This composition comprises an effective amount of ibuprofen or one of its pharmaceutically acceptable salts; a pharmaceutically acceptable effervescent system comprising at least one alkali metal carbonate and at least one organic acid, preferably in a sufficient amount to give a pH below about 8; and at least one pharmaceutically acceptable antioxidant in a sufficient amount to stabilize the ibuprofen. This composition has a remarkable stability both in powder form and in tablet form.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: October 22, 1996
    Assignee: Laboratories UPSA
    Inventors: Nicole Bru-Magniez, Jean-Fran.cedilla.ois Cordoliani, Gerard Thauvin, Jehan-Yves Drouin
  • Adenosine derivatives, their methods of preparation and pharmaceutical compositions in which they are present
    Patent number: 5219839
    Abstract: The present invention relates to the derivatives of the formula ##STR1## and the corresponding enantiomers and diastereoisomers and, if appropriate, their addition salts, and to their use in therapeutics, especially in the central nervous system as analgesics, anticonvulsants, antiepileptics, anxiolytics, antidepressants and neuroprotectors, and in the cardiovascular system as antiarrhythmics, antihypertensives and platelet aggregation inhibitors.
    Type: Grant
    Filed: March 2, 1992
    Date of Patent: June 15, 1993
    Assignee: Laboratories UPSA
    Inventors: Nicole Bru-Magniez, Timur Gungor, Jean-Marie Teulon