Patents Assigned to Laila Impex
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Patent number: 11122829Abstract: The invention discloses novel dietary supplements or herbal product comprising at least one ingredient selected from the extracts or fractions derived from Bauhinia racemosa fruit, Cassia auriculata, Mangifera indica stem bark, Woodfordia fruticosa tender stem and Acacia nilotica fruit or their compositions in combination with at least one compound selected from biological actives, herbal extracts, minerals, amino acids, proteins, vitamins, excipient, diluent or carrier as a natural energy enhancer to provide an onset and steady maintenance of energy and for improving muscle strength, muscle mass and mental alertness, for treating sarcopenia and muscular atrophy in a warm blooded animal or mammal in need thereof.Type: GrantFiled: November 20, 2018Date of Patent: September 21, 2021Assignee: Laila ImpexInventors: Ganga Raju Gokaraju, Trimurtulu Golakoti, Rama Raju Gokaraju, Kiran Bhupathiraju, Venkata Kanaka Ranga Raju Gokaraju, Krishanu Sengupta, Venkata Krishna Raju Alluri
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Patent number: 8568802Abstract: A process for producing an enriched fraction of tetrahydoxycurcumin containing, tetrahydroxycurcumin, demethylcurcumin, demethylmonodemethoxycurcumin and bisd.emethoxycurcumin and colorless tetrahydroderivatives thereof. The process consists of demethylation of natural curcumins, obtained, in turn, from the organic solvent extract of turmeric from Curcuma species. The said enriched fraction of tetrahydroxycurcumin is subjected to hydrogenation to get colorless tetrahydrotetrahydroxycurcumin enriched fraction. The enriched fractions of tetrahydroxycurcumin and colorless tetrahydrotetrahydroxycurcumin exhibits potent antioxidative action and reduces inflammation.Type: GrantFiled: October 13, 2005Date of Patent: October 29, 2013Assignee: Laila ImpexInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Subbaraju Gottumukkala, Venkateswarlu Somepalli
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Patent number: 8541381Abstract: This invention describes a process for producing a fraction enriched with jujubogenin and psudojujubogenin lycosides from Bacopa species, wherein the total Bacopa saponin concentration is up to 100% when estimated by HPLC method of analysis. The present invention also describes the processes for the enrichment of new compositions and individual saponin compounds from Bacopa monnieri to more than 95% purity. It further describes an analytical HPLC method for the estimation of total Bacopa saponin fraction and its use in therapeutic applications. This invention also includes two Bacopa saponin 3-O-[?-D-glucopyranosyl-(1?3)-?-D-glucopyranosyl] jujubogenin and 3-O-[?-D-glucopyranosyl-(1?3)-?-D-glucopyranosyl] pseudojujubogenin herein referred to as bacopaside N1 of general formula (1) and bacopaside N2 of general formula (2) respectively.Type: GrantFiled: May 3, 2005Date of Patent: September 24, 2013Assignee: Laila ImpexInventors: Raju Gokaraju Ganga, Raju Gokaraju Rama, Subbaraju Gottumukkala Venkata, Trimurtulu Golakoti, Sivaramakrishna Chillara
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Patent number: 8524769Abstract: The invention relates to a process for producing a fraction enriched upto 100% of 3-O-acetyl-11-keto-?-boswellic acid. An organic solvent extract of gum resin from Boswellia species is first subjected to oxidation and then acetylation or vice versa. This converts the less potent boswellic acids present in the fraction to AKBA. This treated fraction is subjected to further purification and separation by chromatographic separation techniques to enhance its purity and to remove contaminants therefrom. This process provide an access to a fraction enriched in 10-100% AKBA for therapeutic applications.Type: GrantFiled: March 5, 2002Date of Patent: September 3, 2013Assignee: Laila ImpexInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Subbaraju Gottumukkala, Trimurtulu Golakoti, Sridhar Pratha
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Patent number: 8420132Abstract: Disclosed herein are novel dietary supplement compositions comprising enriched 3-O-acetyl-11-keto-?-boswellic acid and enriched demethylated curcuminoids, wherein the composition exhibits anti-inflammatory, antiulcerogenic and anti-oxidant activities. Also disclosed are novel compositions comprising enriched 3-O-acetyl-11-keto-?-boswellic acid, enriched demethylated curcuminoids that have a synergistic effect on specific inhibition of—COX-2 and 5-LOX activity and optionally containing glucosamine, resveratrol, garlic extract, chondroitin, methlysulphonymethane, bromelain, serratiopeptidase, quercitine, gallic acid, caffeic acid, green tea extract, aspirin and ibuprofen.Type: GrantFiled: May 3, 2012Date of Patent: April 16, 2013Assignee: Laila ImpexInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Venkateswarlu Somepalli
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Publication number: 20120220657Abstract: Disclosed herein are novel dietary supplement compositions comprising enriched 3-O-acetyl-11-keto-?-boswellic acid and enriched demethylated curcuminoids, wherein the composition exhibits anti-inflammatory, antiulcerogenic and anti-oxidant activities. Also disclosed are novel compositions comprising enriched 3-O-acetyl-11-keto-?-boswellic acid, enriched demethylated curcuminoids that have a synergistic effect on specific inhibition of—COX-2 and 5-LOX activity and optionally containing glucosamine, resveratrol, garlic extract, chondroitin, methlysulphonymethane, bromelain, serratiopeptidase, quercitine, gallic acid, caffeic acid, green tea extract, aspirin and ibuprofen.Type: ApplicationFiled: May 3, 2012Publication date: August 30, 2012Applicant: LAILA IMPEXInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Venkateswarlu Somepalli
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Patent number: 8226989Abstract: Herbal compositions having anti-adipocyte fatty acid-binding protein (aP2), anti-5-lipoxygenase-activating protein (FLAP) and anti-Cysteinyl Leukotriene (CysLT)-1 receptor expression activity contain an extract of Boswellia serrata. More particularly, these herbal compositions comprise an effective amount of an enriched Boswellia extract containing from 10% to 99% by weight of 3-0-acetyl-11-keto-?-boswellic acid; and an effective amount of a second extract selected from the group consisting of an extract of Aegle marmelos, an extract of Zingiber officinale, an extract of Garcinia mangostana, and mixtures thereof. These may be used in dietary supplements or pharmaceutical formulations for controlling diseases associated with or related to inflammation. These diseases in particular include respiratory disorders such as asthma, allergic rhinitis, hay fever, type-1 hypersensitivity and mild allergies. The compositions can also be useful for skin care.Type: GrantFiled: June 3, 2009Date of Patent: July 24, 2012Assignee: Laila ImpexInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Golakoti Trimurtulu, Sivaramakrishna Chillara, Krishanu Sengupta, Kiran Bhupathiraju
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Patent number: 8192768Abstract: Disclosed herein are novel dietary supplement compositions comprising enriched 3-O-acetyl-11-keto-?-boswellic acid and enriched demethylated curcuminoids, wherein the composition exhibits anti-inflammatory, antiulcerogenic and antioxidant activities. Also disclosed are novel compositions comprising enriched 3-O-acetyl-11-keto-?-boswellic acid, enriched demethylated curcuminoids that have a synergistic effect on specific inhibition of—COX-2 and 5-LOX activity and optionally containing glucosamine, resveratrol, garlic extract, chondroitin, methlysulphonymethane, bromelain, serratiopeptidase, quercitine, gallic acid, caffeic acid, green tea extract, aspirin and ibuprofen.Type: GrantFiled: April 3, 2007Date of Patent: June 5, 2012Assignee: Laila ImpexInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Vendateswarlu Somepalli
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Patent number: 7780997Abstract: The present invention relates to pharmaceutically active extracts of Vitex leucoxylon exhibiting hypoglycemic and anti-inflammatory properties. This extract is suitable for administrating to animals and humans in treating diabetes, liver disorders and related inflammatory diseases. The extract is found suitable for treating insulin and non-insulin diabetes mellitus.Type: GrantFiled: September 5, 2005Date of Patent: August 24, 2010Assignee: Laila ImpexInventors: Gokaraju Ganga Raju, Gokaraju Rama Raju, Gottumukkala Venkata Subbaraju, Somepalli Venkateswarlu
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Publication number: 20100168248Abstract: A process for producing an enriched fraction of tetrahydoxycurcumin containing, tetrahydroxycurcumin, demethylcurcumin, demethylmonodemethoxycurcumin and bisd.emethoxycurcumin and colorless tetrahydroderivatives thereof. The process consists of demethylation of natural curcumins, obtained, in turn, from the organic solvent extract of turmeric from Curcuma species. The said enriched fraction of tetrahydroxycurcumin is subjected to hydrogenation to get colorless tetrahydrotetrahydroxycurcumin enriched fraction. The enriched fractions of tetrahydroxycurcumin and colorless tetrahydrotetrahydroxycurcumin exhibits potent antioxidative action and reduces inflammation.Type: ApplicationFiled: October 13, 2005Publication date: July 1, 2010Applicant: LAILA IMPEXInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Subbaraju Gottumukkala, Venkateswarlu Somepalli
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Patent number: 7741370Abstract: This invention relates to new double salts of (?)-hydroxycitric acid with group II metals. Preferred double salts are calcium and magnesium double salts of hydroxycitric acid of the formula II. This invention also includes a process for the preparation of these double salts by the addition of one metal compound from group II to (?)-hydroxycitric acid solution followed by the addition of other metal compound solution from group II. These double salts are tasteless and are soluble in water. They are useful as dietary supplements and in beverages.Type: GrantFiled: April 19, 2004Date of Patent: June 22, 2010Assignee: Laila ImpexInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Subbaraju Gottumukkala, Venkateswarlu Somepalli
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Publication number: 20100112101Abstract: The present invention discloses bio-efficacy and bio-availability enhancing composition comprising, an effective amount of stevia compound selected from raw powder or extract, or fraction(s) or compound(s) or combinations thereof derived from the whole plant or plant parts of genus Stevia, preferably leaves of Stevia rebaudiana for enhancing the bio-availability and bio-efficacy of therapeutic agents, cosmetic agents, supplements, food ingredients and beverages selected from but not limited to pharmaceutical drugs, nutrients (micro and macro nutrients), vitamins, minerals, Proteins, amino acids, enzymes, nutraceuticals, herbal drugs/products and antioxidants.Type: ApplicationFiled: November 2, 2009Publication date: May 6, 2010Applicant: LAILA IMPEXInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Cletus D'souza, Elizabeth Frank
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Publication number: 20100098676Abstract: Disclosed herein are novel dietary supplement compositions comprising enriched 3-O-acetyl-11-keto-?-boswellic acid and enriched demethylated curcuminoids, wherein the composition exhibits anti-inflammatory, antiulcerogenic and antioxidant activities. Also disclosed are novel compositions comprising enriched 3-O-acetyl-11-keto-?-boswellic acid, enriched demethylated curcuminoids that have a synergistic effect on specific inhibition of—COX-2 and 5-LOX activity and optionally containing glucosamine, resveratrol, garlic extract, chondroitin, methlysulphonymethane, bromelain, serratiopeptidase, quercitine, gallic acid, caffeic acid, green tea extract, aspirin and ibuprofen.Type: ApplicationFiled: April 3, 2007Publication date: April 22, 2010Applicant: LAILA IMPEXInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Vendateswarlu somepalli
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Publication number: 20090298941Abstract: Herbal compositions having anti-adipocyte fatty acid-binding protein (aP2), anti-5-lipoxygenase-activating protein (FLAP) and anti-Cysteinyl Leukotriene (CysLT)-1 receptor expression activity contain an extract of Boswellia serrata. More particularly, these herbal compositions comprise an effective amount of an enriched Boswellia extract containing from 10% to 99% by weight of 3-0-acetyl-11-keto-?-boswellic acid; and an effective amount of a second extract selected from the group consisting of an extract of Aegle marmelos, an extract of Zingiber officinale, an extract of Garcinia mangostana, and mixtures thereof. These may be used in dietary supplements or pharmaceutical formulations for controlling diseases associated with or related to inflammation. These diseases in particular include respiratory disorders such as asthma, allergic rhinitis, hay fever, type-1 hypersensitivity and mild allergies. The compositions can also be useful for skin care.Type: ApplicationFiled: June 3, 2009Publication date: December 3, 2009Applicant: LAILA IMPEXInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Golokoti Trimurtulu, Sivaramakrishna Chillara, Krishanu Sengupta, Kiran Bhupathiraju
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Patent number: 7208615Abstract: This invention relates to novel triple salts of (?)-hydroxycitric acid having the general formula 1 wherein X, Y are selected from zinc or group IIA metal and Z is selected from group IA metal of the Periodic Table. Preferred salts are triple metal salts of calcium, magnesium or zinc and potassium. This invention also includes a process for preparing the triple salts by adding stiochiometric amounts of aqueous solutions of the compounds of the desired metal to an aqueous solution of (?)-HCA. Preferably an extract from garcinia fruit ring is used as a starting material. Compounds of this invention are substantially tastless, odorless and highly water soluble and find use in beverages and in neutraceuticals.Type: GrantFiled: March 9, 2004Date of Patent: April 24, 2007Assignee: Laila ImpexInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Subbaraju Gottumukkala, Venkateswarlu Somepalli
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Patent number: 7026518Abstract: Novel resveratrol analogs that are potent antioxidants.Type: GrantFiled: June 25, 2002Date of Patent: April 11, 2006Assignee: Laila ImpexInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Subbaraju Gottumukkala, Venkateswarlu Somepalli
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Patent number: 6900356Abstract: This invention relates to novel polyhydroxy curcumins of the formula (I), wherein R and R1 may be same or different and are selected from H, OH and OCH3. This invention also includes a process for synthesising the above polyhydroxy curcumins by reacting substituted aromatic alhehydes with a diketone in the presence of boron oxide, alkyl borate and a primary or secondary amine catalyst. If desired, the resulting compounds can be deprotected by known means. These compounds are used as anti-oxidants.Type: GrantFiled: April 18, 2001Date of Patent: May 31, 2005Assignee: Laila ImpexInventors: Ganga Raju Gokaraju, Venkata Subbaraju Gottumukkala, Venkateswarlu Somepalli
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Patent number: 6875891Abstract: This invention relates to a novel process for preparing highly water soluble alkaline earth metal and alkali metal double salts of hydroxycitric acid. These salts are practically odourless and has negligible taste and are therefor useful as nutraceuticals. Aqueous extract of the fruits belonging to Garcinia species are treated to precipitate its alkaline earth metal salts such as the calcium salt. This sparingly soluble product is dissolved in alkali hydroxide and the pH of the solution is adjusted by adding purified extract of the fruit rind. Ca/Na or Ca/K double salts are particularly useful.Type: GrantFiled: March 19, 2004Date of Patent: April 5, 2005Assignee: Laila ImpexInventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Subbaraju Gottumukkala, Sridhar Pratha