Patents Assigned to Leibniz—Institut für Analytische Wissenschaften—ISAS—e.V.
  • Patent number: 9778248
    Abstract: With a method for measurement of thrombocyte function, a solution is created, by which the sensitivity of individual thrombocytes can be measured with the least possible apparatus effort, with high throughput, by passing a liquid thrombocyte solution, in which the thrombocytes are present in isolated form, into a microfluidic chamber and brought into contact with at least one stimulant, wherein an electrical field directed transverse to the entry direction of the thrombocyte solution is applied to the chamber, and the movement path of the thrombocytes in the electrical field is observed and evaluated, in such a manner that thrombocytes having a movement path directed in the direction toward the minus pole of the electrical field are classified as non-activated thrombocytes, and thrombocytes having a movement path directed in the direction toward the plus pole of the electrical field are classified as activated thrombocytes.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: October 3, 2017
    Assignee: Leibniz—Institut fuer Analytische Wissenschaften—ISAS—e.V.
    Inventors: Jonathan West, Dirk Janasek, Albert Sickmann
  • Patent number: 8873048
    Abstract: A spectrometer assembly (10), comprising an Echelle grating (18; 46) for dispersing radiation entering the spectrometer assembly (10) in a main dispersion direction, and a dispersion assembly (16; 40) for dispersing a parallel radiation bundle generated from the radiation entering the spectrometer assembly in a lateral dispersion direction, is characterized in that the dispersion assembly (16; 40) is reflective, and the dispersion assembly (16; 40) is arranged relative to the Echelle grating (18; 46) in such a way that the parallel radiation bundle is reflected in the direction of the Echelle grating. The Echelle grating (18; 46) may be arranged in such a way that the dispersed radiation is reflected back to the dispersion assembly (16; 40).
    Type: Grant
    Filed: December 13, 2010
    Date of Patent: October 28, 2014
    Assignee: Leibniz—Institut für Analytische Wissenschaften—ISAS—e.V.
    Inventors: Stefan Florek, Michael Okruss, Helmut Becker-Ross
  • Patent number: 8587786
    Abstract: The invention relates to a surface plasmon resonance spectrometer comprising a radiation source that emits substantially monochromatic radiation, a sensor surface, an optical arrangement for lighting the sensor surface by the radiation emitted from the radiation source such that surface plasmons can be created in the sensor surface, a detector having a plurality of image elements and observation optics for depicting the radiation reflected by the sensor surface on the detector, characterized in that the resolution capability of the observation optics and of the detector is larger than the resolution that can be obtained by the deflection-limited radiation source.
    Type: Grant
    Filed: August 26, 2011
    Date of Patent: November 19, 2013
    Assignee: Leibniz—Institut für Analytische Wissenschaften—ISAS—e.V.
    Inventor: Alexander Zybin
  • Patent number: 7973279
    Abstract: A solution is supposed to be created with a method for generating positively and/or negatively ionized gas analytes for gas analysis in an ion mobility spectrometer or in a mass spectrometer, with which method the gas analyte can be ionized without the restrictions of previous ionization methods for gas analysis in an ion mobility spectrometer or in a mass spectrometer, forming positive and/or negative ions. This is achieved in that the positive and/or negative gas ions are generated by means of a plasma, which is brought about by means of a dielectrically inhibited discharge, whereby the dielectrically inhibited discharge is produced in that a noble gas is passed in through a capillary made of a dielectric material, whereby an alternating voltage is applied by means of two electrically insulated electrodes disposed on the capillary adjacent to the exit region of the capillary, and the gas analyte is passed to the exit region outside of the capillary.
    Type: Grant
    Filed: September 14, 2007
    Date of Patent: July 5, 2011
    Assignee: Leibniz—Institut für Analytische Wissenschaften—ISAS—e.V.
    Inventors: Joerg Ingo Baumbach, Wolfgang Vautz, Antje Michels, Joachim Franzke