Abstract: Sleeve catheters having an interactive device near their distal ends are provided for introduction while disposed over conventional interventional and imaging catheters. Exemplary interactive devices on the sleeve catheters include ultrasonic imaging arrays, drug delivery lumens, and the like. The sleeve catheters are most commonly used with angioplasty catheters, stent placement catheters, atherectomy catheters, and the like.

Abstract: A perfusion shunt device is used in conjunction with balloon catheters to provide blood perfusion across an inflated balloon in a blood vessel. The perfusion shunt device comprises a flexible conduit structure having one or more blood perfusion paths formed from a proximal end to a distal end thereof. The flexible conduit structure is usually attached directly or indirectly to a proximal shaft structure. Discrete anchors or expansible sleeves or cages are provided for locating the conduit structure over the balloon on the catheter. The flexible conduit structure will not be directly attached to the balloon, but rather will be secured at locations distal to an proximal of the balloon. In this way, constriction and distortion of the conduit structure and/or balloon resulting from balloon expansion are minimized. The device may be loaded over a conventional angioplasty balloon catheter outside of the blood vessel being treated, either before or after an angioplasty procedure.

Abstract: A perfusion shunt device is used in conjunction with balloon catheters to provide blood perfusion across an inflated balloon in a blood vessel. The perfusion shunt device comprises a flexible conduit structure having one or more blood perfusion paths formed from a proximal end to a distal end thereof. The flexible conduit structure is usually attached directly or indirectly to a proximal shaft structure. Discrete anchors or expansible sleeves or cages are provided for locating the conduit structure over the balloon on the catheter. The flexible conduit structure will not be directly attached to the balloon, but rather will be secured at locations distal to an proximal of the balloon. In this way, constriction and distortion of the conduit structure and/or balloon resulting from balloon expansion are minimized. The device may be loaded over a conventional angioplasty balloon catheter within or outside of the blood vessel being treated, either before or after an angioplasty procedure.

Abstract: A multi-function proximal end adapter (70, 86, 100) for a catheter (22) includes a hollow body (6) defining an axial lumen (8) extending between its proximal and distal ends (12, 10). An annular radially compressible seal (48) is positioned within the body along the axial lumen. A seal driver (58) is threadably mounted to the body and has a hollow extension (60) with a distal end adapted to axially compress the seal causing a radially inward deflection of the seal when the seal driver is threaded onto the body thereby providing a good seal against and securement for an object (such as a catheter or guide wire) passing through the axial lumen of the body. At least a portion of the proximal end of the axial lumen is defined by an internal tapered surface (36) sized to matingly and sealingly engage an external tapered surface (44) of a Luer lock connector (40) after the seal driver has been removed from the proximal end of the body.

Abstract: An intravascular catheter provides means for infusing an agent into a treatment site in a body lumen and means for deploying the infusing means adjacent the treatment site which operate independently of one another. In a preferred embodiment, a flexible catheter body has an expansion member attached to its distal end in communication with an inflation passage, and an infusion array disposed about the expansion member in communication with one or more delivery passages. The infusion array includes a plurality of delivery conduits having laterally oriented orifices. The delivery conduits may be extended radially from the catheter body to contact a treatment site by expanding the expansion member with an inflation fluid. An agent may be introduced into the delivery passages and infused into the treatment site through orifices in the delivery conduits. The expansion member may be expanded for dilatation of the lumen before, during, or after infusion.

Abstract: An intravascular treatment apparatus provides means for infusing a treatment site with an agent and means for positioning the delivery interface against the treatment site which operate independently of one another. In a preferred embodiment, the apparatus includes a flexible body having a deflectable support frame at its distal end. A plurality of platforms, each comprising a plenum and a delivery interface, is coupled to the support frame. The platforms may be deployed radially from the body by deflecting the support frame using an actuator shaft extending through a passage in the body. The platforms are connected to a supply passage through the body. In this way, the apparatus may be positioned within a body lumen, usually an artery, with the platforms near a treatment site. By actuating the actuator shaft, the platforms are deployed against the treatment site.