Patents Assigned to LRE Medical GmbH
-
Patent number: 9335268Abstract: A device (10) and a method for analyzing a sample (16) containing fluorophores use a light source (12) emitting light (?ex) onto the sample (16), and onto a fluorescence standard (14). The fluorophores of the sample (16), given an immission of light of a first wavelength (?ex1), have a first excitation efficiency and, given an immission of light of a second wavelength (?ex2), have a second excitation efficiency. The fluorescence standard (14), given the same immissions of light, has a third excitation efficiency and, a fourth excitation efficiency. An optical element (20) which is arranged between the light source (12) and the sample (16) and/or (12) the fluorescence standard (14) adapts, due to its optical property, a first difference between the first excitation efficiency and the second excitation efficiency and a second difference between the third excitation efficiency and the fourth excitation efficiency to each other.Type: GrantFiled: January 28, 2015Date of Patent: May 10, 2016Assignee: LRE Medical GmbHInventors: Rafael Egger, Jörg Zeiner
-
Patent number: 9006685Abstract: A device (10) and a method for analyzing a sample (16) containing fluorophores use a light source (12) emitting light (?ex) onto the sample (16), and onto a fluorescence standard (14). The fluorophores of the sample (16), given an immission of light of a first wavelength (?ex1), have a first excitation efficiency and, given an immission of light of a second wavelength (?ex2), have a second excitation efficiency. The fluorescence standard (14), given the same immissions of light, has a third excitation efficiency and, a fourth excitation efficiency. An optical element (20) which is arranged between the light source (12) and the sample (16) and/or (12) the fluorescence standard (14) adapts, due to its optical property, a first difference between the first excitation efficiency and the second excitation efficiency and a second difference between the third excitation efficiency and the fourth excitation efficiency to each other.Type: GrantFiled: April 11, 2012Date of Patent: April 14, 2015Assignee: LRE Medical GmbHInventors: Rafael Egger, Jörg Zeiner
-
Patent number: 8334522Abstract: The invention concerns methods and apparatuses for quantitatively determining the concentration of fluorophores of a substance in a sample. A constant portion of the reference light of a reference light wave length (?r) emitted by a reference light source is coupled in by an optical element in the direction of a receiving element. A first value corresponding to the portion of the reference light coupled in which is incident on the receiving element is detected. The sample is irradiated with the excitation light of an excitation wave length (?ex) emitted by an excitation light source. A second value corresponding to the portion of the fluorescent light of an emission wave length (?em) emitted by the sample which is incident on the receiving element. The ratio of the second value to the first value is determined. The number of fluorophores in the substance is determined based on the ratio.Type: GrantFiled: November 12, 2009Date of Patent: December 18, 2012Assignee: LRE Medical GmbHInventor: Rafael Egger
-
Publication number: 20120261591Abstract: A device (10) and a method for analyzing a sample (16) containing fluorophores use a light source (12) emitting light (?ex) onto the sample (16), and onto a fluorescence standard (14). The fluorophores of the sample (16), given an immission of light of a first wavelength (?ex1), have a first excitation efficiency and, given an immission of light of a second wavelength (?ex2), have a second excitation efficiency. The fluorescence standard (14), given the same immissions of light, has a third excitation efficiency and, a fourth excitation efficiency. An optical element (20) which is arranged between the light source (12) and the sample (16) and/or (12) the fluorescence standard (14) adapts, due to its optical property, a first difference between the first excitation efficiency and the second excitation efficiency and a second difference between the third excitation efficiency and the fourth excitation efficiency to each other.Type: ApplicationFiled: April 11, 2012Publication date: October 18, 2012Applicant: LRE MEDICAL GMBH, ESTERLINE CORPORATIONInventors: Rafael Egger, Jörg Zeiner
-
Patent number: 8045172Abstract: In a method for determining the concentration of at least one substance in a liquid the liquid is applied onto a test strip containing at least one test zone, wherein an optical sensor arrangement is moved step-by-step in a first direction over the surface of the test strip while the test trip is at the same time irradiated with light of a predetermined wave length and wherein in each step the radiation reflected from the surface of the test strip is measured, and wherein in each measurement step the test strip surface is irradiated alternately with light of at least two different wave lengths and the irradiation is measured at the same time and the difference between the measurement signals obtained in each measurement step using irradiation light of different wave lengths is analyzed.Type: GrantFiled: June 19, 2009Date of Patent: October 25, 2011Assignee: LRE Medical GmbHInventor: Rafael Egger
-
Publication number: 20100117003Abstract: The invention concerns a method and an apparatus for the quantitative determination of the concentration of fluorophores of at least one substance in a sample. A constant portion of the reference light of a reference light wave length (?r) emitted by a reference light source (28) is coupled in by an optical element (REM) in the direction of a receiving element (38). A first measured value is detected which corresponds to the portion of the reference light coupled in which is incident on the receiving element (38). The sample is irradiated with the excitation light of an excitation wave length (?ex) emitted by an excitation light source (26). A second measured valued is detected which corresponds to the portion of the fluorescent light of an emission wave length (?em) emitted by the sample which is incident on the receiving element (38). The ratio (Emes2/Es2) of the second measured value (Emes2) to the first measured value (Es2) is determined.Type: ApplicationFiled: November 12, 2009Publication date: May 13, 2010Applicant: LRE Medical GmbHInventor: Rafael Egger
-
Publication number: 20090323070Abstract: In a method for determining the concentration of at least one substance in a liquid the liquid is applied onto a test strip containing at least one test zone, wherein an optical sensor arrangement is moved step-by-step in a first direction over the surface of the test strip while the test trip is at the same time irradiated with light of a predetermined wave length and wherein in each step the radiation reflected from the surface of the test strip is measured, and wherein in each measurement step the test strip surface is irradiated alternately with light of at least two different wave lengths and the irradiation is measured at the same time and the difference between the measurement signals obtained in each measurement step using irradiation light of different wave lengths is analyzed.Type: ApplicationFiled: June 19, 2009Publication date: December 31, 2009Applicant: LRE Medical GmbHInventor: Rafael Egger
-
Patent number: 7507371Abstract: The invention concerns a method and an apparatus for disinfecting a cuvette cover. The opening of a cuvette (14) containing a test fluid is temporarily covered while the cuvette is at a processing station. The surface of the cover facing the cuvette opening in the lifted condition of the cover is heated to a temperature suitable for the killing of microorganisms on the cover.Type: GrantFiled: May 24, 2005Date of Patent: March 24, 2009Assignee: LRE Medical GmbHInventor: Klaus Deuter
-
Patent number: 7431885Abstract: A measuring device for the amperometric measurement of test strips 12, each having a test field moistenable by a liquid to be investigated and having measuring electrodes associated with the test field. The device includes at least one test strip receiver 20 for the insertion of a test strip 12, first contact elements arranged in the region of the strip receiver 20 for contacting the measuring electrodes of a test strip 12 located in the strip receiver 20, and an evaluation and control circuit. The strip receiver 20 is formed with a separate unitary housing which on its external side has second external contact elements 50 electrically connected with the first internal contact elements. The external contact elements 50 are designed for contacting opposite contact elements 16 connected with the evaluation and control circuit.Type: GrantFiled: May 23, 2007Date of Patent: October 7, 2008Assignee: LRE Medical GmbHInventors: Norbert Pöllmann, Wolfgang Heider, Genrich Siris
-
Publication number: 20070274866Abstract: A measuring device for the amperometric measurement of test strips 12, each having a test field moistenable by a liquid to be investigated and having measuring electrodes associated with the test field. The device includes at least one test strip receiver 20 for the insertion of a test strip 12, first contact elements arranged in the region of the strip receiver 20 for contacting the measuring electrodes of a test strip 12 located in the strip receiver 20, and an evaluation and control circuit. The strip receiver 20 is formed with a separate unitary housing which on its external side has second external contact elements 50 electrically connected with the first internal contact elements. The external contact elements 50 are designed for contacting opposite contact elements 16 connected with the evaluation and control circuit.Type: ApplicationFiled: May 23, 2007Publication date: November 29, 2007Applicant: LRE Medical GmbHInventors: Norbert Pollmann, Wolfgang Heider, Genrich Siris
-
Patent number: 7240565Abstract: A strip ejector removes a longitudinal test strip (12), which has at least one test field for wetting by a fluid, from a measuring device that optically or amperemetrically measures such test strip. The ejector includes a clamping jaw holder (14), and at least two clamping jaws (18) arranged on the clamping jaw holder at a distance from one another. The jaws are moveable relative to one another between a freeing position in which the spacing between their clamping surfaces is larger than the width of a test strip (12), and a clamping position in which their clamping faces respectively engage parallel edges (22) of the test strip (12). An actuating element (24) moveably supported on the clamping jaw holder (14) has at least one control surface 30 arranged at an angle to the movement direction of the actuating element.Type: GrantFiled: May 5, 2005Date of Patent: July 10, 2007Assignee: LRE Medical GmbHInventors: Martin Eisenmann, Otto Rzehak, Ralph Pinzenöller, Johann Stapfner, Norbert Pöllmann
-
Publication number: 20050265891Abstract: The invention concerns a method and an apparatus for disinfecting a cuvette cover. The opening of a cuvette (14) containing a test fluid is temporarily covered while the cuvette is at a processing station. The surface of the cover facing the cuvette opening in the lifted condition of the cover is heated to a temperature suitable for the killing of microorganisms on the cover.Type: ApplicationFiled: May 24, 2005Publication date: December 1, 2005Applicant: LRE Medical GmbHInventor: Klaus Deuter
-
Publication number: 20050256382Abstract: A strip ejector removes a longitudinal test strip (12), which has at least one test field for wetting by a fluid, from a measuring device that optically or amperemetrically measures such test strip. The ejector includes a clamping jaw holder (14), and at least two clamping jaws (18) arranged on the clamping jaw holder at a distance from one another. The jaws are moveable relative to one another between a freeing position in which the spacing between their clamping surfaces is larger than the width of a test strip (12), and a clamping position in which their clamping faces respectively engage parallel edges (22) of the test strip (12). An actuating element (24) moveably supported on the clamping jaw holder (14) has at least one control surface 30 arranged at an angle to the movement direction of the actuating element.Type: ApplicationFiled: May 5, 2005Publication date: November 17, 2005Applicant: LRE Medical GmbHInventors: Martin Eisenmann, Otto Rzehak, Ralph Pinzenoller, Johann Stapfner, Norbert Pollmann