Abstract: An electro-optical sensor senses marks on a sheet which travels longitudinally with respect to a printed circuit board, carrying linear arrays of light sources (LEDs) and photodetectors and optics which define zones displaced laterally across the width of a sheet of paper, longitudinal columns of which can contain marks, the presence and absence of which marks is detected by the sensor. The sensor is especially adapted for use in detecting marks which indicate votes on paper ballots in electronic, computerized vote counting apparatus.

Abstract: The quality of images produced by confocal microscopy, and especially scanning laser confocal microscopy, is enhanced especially for images obtained in turbid mediums such as many biological tissue specimens, by reducing speckle from scatterers that exist outside (above and below) the focal plane region which is being imaged by utilizing sheared beams, both of which are focused to spots in the focal or image plane (region of interest) and polarizing the beams to have opposite senses of circular polarization (right and left handed circular polarization). The return light from the image plane of certain polarization is detected after passing through the confocal aperture of the confocal microscope. Light from scatterers outside the region of interest, which are illuminated by both of the sheared beams, interfere thereby reducing speckle due to such scatterers, and particularly scatters which are adjacent to the image plane.

Abstract: The quality of images produced by confocal microscopy, and especially scanning laser confocal microscopy, is enhanced especially for images obtained in turbid mediums such as many biological tissue specimens, by reducing speckle from scatterers that exist outside (above and below) the section which is being imaged by utilizing sheared beams, both of which are focused to laterally or vertically offset spots and polarizing the beams to have opposite senses of circular polarization (right and left handed circular polarization). The return light from the section of certain polarization is detected after passing through the confocal aperture of the confocal microscope. Images can be formed using optical coherence detection of the return light. Light from scatterers outside the section of interest, which are illuminated by both of the sheared beams, interfere thereby reducing speckle due to such scatterers, and particularly scatters which are adjacent to the section being imaged.

Abstract: An improved system for cellular surgery which includes a laser for producing a laser beam, and confocal optics for scanning and focusing the laser beam in tissue and generating confocal images of the tissue in accordance with returned light from the tissue. The confocal images are visualized on a display. The system includes a controller for enabling the operator to select one or more cells of the tissue in the displayed confocal images for surgical treatment. The controller operates the laser and confocal optics in a first mode to treat the tissue when the confocal optics focus the laser beam at at least one region associated with the selected cells in the tissue, but at all other times operates the laser and confocal optics in a second mode which does not damage the tissue.

Abstract: A system is provided having a clamping apparatus with first and second members, which are spaced apart from each other. An attachment mechanism is connected to the first member for attaching the apparatus to a confocal imaging system. This attachment mechanism has a surface with a window facing the tissue to be examined. Opposing this surface is a third member connected to the second member. A clamping mechanism includes the first and second members for clamping the tissue between the surface of the attachment mechanism and the surface of the third member, thereby stabilizing the tissue to the confocal imaging system. The window of the attachment mechanism presents the clamped tissue to the confocal imaging system.

Abstract: A scanning reflection profilometry system utilizes an objective lens which focuses a beam at the surface under test and measures the profile of the surface (its height variations) in accordance with the amount of defocus of the reflected beam. Surface profile distortion which is focus dependent is reduced through the use of a transparent mask over the aperture of the lens in the path of the beam which is incident on and reflected from the surface under test and which covers a portion but not all of the aperture. A photodetector upon which the reflected beam is incident provides output signals representing the change in profile. The system has height sensitivity characteristic of a small spot size on the surface without signal distortion attributable to the diffraction anomalies associated with small spot sizes. A microprofilometer head having the objective lens and other optics is mounted on flexures and driven to execute reciprocal movement so as to scan the surface under test.

Abstract: In order to reduce the size of a spectrophotometer having a rotatable diffraction grating and to compensate for longitudinal chromatic aberration and to provide for triangular bandwidth (where the image of the entrance aperture through which the light to be analyzed enters the spectrophotometer is equal in width to the width of exit slit through which the spectral components of each band are passed to a photodetector) thereby enabling high, accurate resolution of spectral line locations and edges of colors to be obtained, the diffraction grating is pivoted about an axis laterally displaced from the grating in the tangential plane, which plane contains substantially all of the light paths in the spectrophotometer. The exit aperture rotates with the grating and has a displacement from the grating in a direction transverse to the direction of displacement of the pivot, which displacement may be in the sagittal plane of the spectrophotometer.

Abstract: A robust spectrophotometer (also known as a color spectrometer or colorimeter) is self contained in a housing which is adapted to be held-held and has all of the electrical, optical and electro optic elements mounted on a board captured within the housing at one end of which light from a sample is restricted to an object area and projected after being dispersed spectrally, as with a reflection grating, to an image area at a photodetector via a lens which has an optical axis and converges the dispersed light at the image area. The dispersive element is mounted on an arm having a pivot laterally offset from the dispersive element's surface where a diverging beam of light from the object area is incident and is deflected to the image area. The geometry is such that the dispersive element may be rotated to a position where the beam is specularly deflected (zeroth order diffraction), and the spectrometer calibrated when the dispersive element is in the specular reflection/deflection position.

Abstract: A hand held microsurgical instrument for applying laser energy to selected locations (sites) in an area under the skin (or other exposed translucent tissue) to provide localized photothermolysis of underlying tissue at these sites, is described. The laser energy is focused into a spot within the tissue. This spot is of sufficiently small size so that the energy density is sufficient to provide surgical or treatment effects within the tissue without damaging the surface tissue. In dermatology, for example, the technique can be used to destroy endothelial cells in blood vessels which are desired to be removed, such spider veins (nevi) in the skin, hair follicles to prevent hair growth therefrom, or other microsurgical procedures. The area is visualized while the laser beam is steered, using a deflection system, in X and Y coordinates.

Abstract: A spectral densitometer system reads dosimeter cards. The cards contain bar codes with information for calibration of the system and for identification of the cards (serial numbers for each card). The densitometer has compartments optically and physically separated by a mechanism which contains a slide for receiving the cards and moving them into alignment with openings which expose the bar code to a bar code scanner in one of the compartments. The compartment containing the scanner also contains a source of illumination which projects through another opening and through a radiation sensitive patch. A scanning spectrophotometer in the other compartment reads the spectrum of the transmitted illumination. The system includes a computer, which may be a separate host computer, connected to the spectrophotometer and the bar code reader via communication ports. The computer computes the dosage based upon the wavelength measurements and the calibration information contained in the bar code.

Abstract: In order to facilitate pathological examination of a lesion in in-vivo tissue, a system and method are provided having a computer system in which both a camera for producing a digital macroscopic picture of the lesion and an imager are coupled to the computer system. The imager is responsive to the computer system and has optics for scanning the lesion to generate images representing microscopic sections of the lesion which provide sufficient information for pathological examination of the lesion. The computer system generates location information, referencing the location in the macroscopic picture of the lesion where the lesion was scanned to the images, and stores data in an electronic file structure which contains at least a representation of the images, a representation of the macroscopic picture, and the location information.

Abstract: A synchronous digital system is disclosed which includes a system clock, a first and a second subsystem, each having a clock input, and a circuit for disabling the clock input to the second subsystem on a regular basis. The effective clock rate of the second subsystem is a fraction of the effective clock rate of the first subsystem.