Abstract: The invention involves isolation of nucleic acid molecules, the expression of which are upregulated by interleukin-9. The amino acid sequences of the proteins which correspond to the nucleic acid molecules show some structural features of cytokines. In addition to the nucleic acid molecules and the proteins, various uses of the molecules are disclosed. The molecules are referred to as T cell inducible factors.
Abstract: A glioblastoma-derived angiogenesis inhibiting factor is described. The material is induced in presence of wild type p53, but not by several mutated forms of p53. Various uses of the material are described.
Type:
Grant
Filed:
November 15, 1996
Date of Patent:
November 23, 1999
Assignee:
Ludwig Institue for Cancer Research
Inventors:
Erwin Van Meir, H.-J. Su Huang, Webster K Cavenee