Patents Assigned to Mallinckrodt Hospital Products IP Limited
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Patent number: 9629358Abstract: Described are systems and methods for monitoring administration of nitric oxide (NO) to ex vivo fluids. Examples of such fluids include blood in extracorporeal membrane oxygenation (ECMO) circuits or perfusion fluids used for preserving ex vivo organs prior to transplanting in a recipient. The systems and methods described herein provide for administering nitric oxide to the fluid, monitoring nitric oxide or a nitric oxide marker in the fluid, and adjusting the nitric oxide administration.Type: GrantFiled: December 3, 2013Date of Patent: April 25, 2017Assignee: Mallinckrodt Hospital Products IP LimitedInventors: Jim Potenziano, Douglas R. Hansell, Jeff Griebel, Eddie Costa, Lisa Cooper
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Patent number: 9616193Abstract: Described are methods and devices for therapeutic or medical gas delivery that utilize at least one proportional control valve and at least one binary control valve. The proportional control valve may be in series with the binary control valve to provide a valve combination capable of pulsing therapeutic gas at different flow rates, depending on the setting of the proportional control valve. Alternatively, the proportional control valve and binary control valve may be in parallel flow paths.Type: GrantFiled: March 14, 2014Date of Patent: April 11, 2017Assignee: Mallinckrodt Hospital Products IP LimitedInventors: Jaron Acker, Thomas Kohlmann, Craig R. Tolmie
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Publication number: 20170072157Abstract: Described are systems and methods for compensating long term sensitivity drift of catalytic type electrochemical gas sensors used in systems for delivering therapeutic nitric oxide (NO) gas to a patient by compensating for drift that may be specific to the sensors atypical use in systems for delivering therapeutic nitric oxide gas to a patient. In at least some instances, the long term sensitivity drift of catalytic type electrochemical gas sensors can be addressed using calibration schedules, which can factor in the absolute change in set dose of NO being delivered to the patient that can drive one or more baseline calibrations. The calibration schedules can be used reduce the amount of times the sensor goes offline. Systems and methods described may factor in in actions occurring at the delivery system and/or aspects of the surrounding environment, prior to performing a baseline calibration, and may postpone the calibration and/or rejected using the sensor's output for the calibration.Type: ApplicationFiled: November 2, 2016Publication date: March 16, 2017Applicant: Mallinckrodt Hospital Products IP LimitedInventors: Craig R. Tolmie, Jeff Milsap, Jaron M. Acker
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Publication number: 20170072153Abstract: Described are systems and methods for compensating long term sensitivity drift of catalytic type electrochemical gas sensors used in systems for delivering therapeutic nitric oxide (NO) gas to a patient by compensating for drift that may be specific to the sensors atypical use in systems for delivering therapeutic nitric oxide gas to a patient. In at least some instances, the long term sensitivity drift of catalytic type electrochemical gas sensors can be addressed using calibration schedules, which can factor in the absolute change in set dose of NO being delivered to the patient that can drive one or more baseline calibrations. The calibration schedules can be used reduce the amount of times the sensor goes offline. Systems and methods described may factor in in actions occurring at the delivery system and/or aspects of the surrounding environment, prior to performing a baseline calibration, and may postpone the calibration and/or rejected using the sensor's output for the calibration.Type: ApplicationFiled: November 2, 2016Publication date: March 16, 2017Applicant: Mallinckrodt Hospital Products IP LimitedInventors: Craig R. Tolmie, Jeff Milsap, Jaron M. Acker
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Publication number: 20170074844Abstract: Described are systems and methods for compensating long term sensitivity drift of catalytic type electrochemical gas sensors used in systems for delivering therapeutic nitric oxide (NO) gas to a patient by compensating for drift that may be specific to the sensors atypical use in systems for delivering therapeutic nitric oxide gas to a patient. In at least some instances, the long term sensitivity drift of catalytic type electrochemical gas sensors can be addressed using calibration schedules, which can factor in the absolute change in set dose of NO being delivered to the patient that can drive one or more baseline calibrations. The calibration schedules can be used reduce the amount of times the sensor goes offline. Systems and methods described may factor in in actions occurring at the delivery system and/or aspects of the surrounding environment, prior to performing a baseline calibration, and may postpone the calibration and/or rejected using the sensor's output for the calibration.Type: ApplicationFiled: November 4, 2016Publication date: March 16, 2017Applicant: Mallinckrodt Hospital Products IP LimitedInventors: Craig R. Tolmie, Jeff Milsap, Jaron M. Acker
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Publication number: 20170074845Abstract: Described are systems and methods for compensating long term sensitivity drift of catalytic type electrochemical gas sensors used in systems for delivering therapeutic nitric oxide (NO) gas to a patient by compensating for drift that may be specific to the sensors atypical use in systems for delivering therapeutic nitric oxide gas to a patient. In at least some instances, the long term sensitivity drift of catalytic type electrochemical gas sensors can be addressed using calibration schedules, which can factor in the absolute change in set dose of NO being delivered to the patient that can drive one or more baseline calibrations. The calibration schedules can be used reduce the amount of times the sensor goes offline. Systems and methods described may factor in in actions occurring at the delivery system and/or aspects of the surrounding environment, prior to performing a baseline calibration, and may postpone the calibration and/or rejected using the sensor's output for the calibration.Type: ApplicationFiled: November 2, 2016Publication date: March 16, 2017Applicant: Mallinckrodt Hospital Products IP LimitedInventors: Craig R. Tolmie, Jeff Milsap, Jaron M. Acker
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Patent number: 9567226Abstract: Apparatus for making at least 99.99% pure gaseous carbon monoxide comprising a reactor vessel, a cooling vessel, a compressor and optionally a chiller, a dryer or a pressurized cylinder. The chiller can be adapted to chill the scrubbed carbon monoxide gas to a temperature in the range of ?30° C. to ?90° C. to remove impurities. The dryer can be adapted to dry the scrubbed gaseous carbon monoxide to remove impurities. The pressurized cylinder can be adapted to store the compressed gaseous carbon monoxide.Type: GrantFiled: February 28, 2014Date of Patent: February 14, 2017Assignee: MALLINCKRODT HOSPITAL PRODUCTS IP LIMITEDInventors: Tammer Mosa, Gerard T. Taylor
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Publication number: 20170021124Abstract: Described are systems and methods for compensating long term sensitivity drift of catalytic type electrochemical gas sensors used in systems for delivering therapeutic nitric oxide (NO) gas to a patient by compensating for drift that may be specific to the sensors atypical use in systems for delivering therapeutic nitric oxide gas to a patient. In at least some instances, the long term sensitivity drift of catalytic type electrochemical gas sensors can be addressed using calibration schedules, which can factor in the absolute change in set dose of NO being delivered to the patient that can drive one or more baseline calibrations. The calibration schedules can be used reduce the amount of times the sensor goes offline. Systems and methods described may factor in in actions occurring at the delivery system and/or aspects of the surrounding environment, prior to performing a baseline calibration, and may postpone the calibration and/or rejected using the sensor's output for the calibration.Type: ApplicationFiled: October 4, 2016Publication date: January 26, 2017Applicant: Mallinckrodt Hospital Products IP LimitedInventors: Craig R. Tolmie, Jeff Milsap, Jaron M. Acker
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Patent number: 9550039Abstract: The present invention generally relates to, amongst other things, systems, devices, materials, and methods that can improve the accuracy and/or precision of nitric oxide therapy by, for example, reducing the dilution of inhaled nitric oxide (NO). As described herein, NO dilution can occur because of various factors. To reduce the dilution of an intended NO dose, various exemplary nasal cannulas, pneumatic configurations, methods of manufacturing, and methods of use, etc. are disclosed.Type: GrantFiled: June 23, 2014Date of Patent: January 24, 2017Assignee: Mallinckrodt Hospital Products IP LimitedInventors: Craig Flanagan, Simon Freed, John Klaus, Thomas Kohlmann, Martin D. Meglasson, Manesh Naidu, Parag Shah
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Patent number: 9550040Abstract: Described are methods for safer nitric oxide delivery, as well as apparatuses for performing these methods. The methods may include detecting the presence or absence of a nasal cannula, and stopping the delivery of nitric oxide or providing an alert if the cannula is disconnected. The methods may also include purging the nasal cannula if it is reconnected after a disconnection or if it is replaced by a new cannula. Other methods pertain to automatic purging of the delivery conduit if the elapsed time between successive deliveries of therapeutic gas exceeds a predetermined period of time.Type: GrantFiled: August 17, 2015Date of Patent: January 24, 2017Assignee: Mallinckrodt Hospital Products IP LimitedInventors: Jaron M. Acker, Thomas Kohlmann
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Publication number: 20170014591Abstract: Described are systems and methods for compensating long term sensitivity drift of catalytic type electrochemical gas sensors used in systems for delivering therapeutic nitric oxide (NO) gas to a patient by compensating for drift that may be specific to the sensors atypical use in systems for delivering therapeutic nitric oxide gas to a patient. In at least some instances, the long term sensitivity drift of catalytic type electrochemical gas sensors can be addressed using calibration schedules, which can factor in the absolute change in set dose of NO being delivered to the patient that can drive one or more baseline calibrations. The calibration schedules can be used reduce the amount of times the sensor goes offline. Systems and methods described may factor in in actions occurring at the delivery system and/or aspects of the surrounding environment, prior to performing a baseline calibration, and may postpone the calibration and/or rejected using the sensor's output for the calibration.Type: ApplicationFiled: September 28, 2016Publication date: January 19, 2017Applicant: Mallinckrodt Hospital Products IP LimitedInventors: Craig R. Tolmie, Jeff Milsap, Jaron M. Acker
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Publication number: 20170014592Abstract: Described are systems and methods for compensating long term sensitivity drift of catalytic type electrochemical gas sensors used in systems for delivering therapeutic nitric oxide (NO) gas to a patient by compensating for drift that may be specific to the sensors atypical use in systems for delivering therapeutic nitric oxide gas to a patient. In at least some instances, the long term sensitivity drift of catalytic type electrochemical gas sensors can be addressed using calibration schedules, which can factor in the absolute change in set dose of NO being delivered to the patient that can drive one or more baseline calibrations. The calibration schedules can be used reduce the amount of times the sensor goes offline. Systems and methods described may factor in in actions occurring at the delivery system and/or aspects of the surrounding environment, prior to performing a baseline calibration, and may postpone the calibration and/or rejected using the sensor's output for the calibration.Type: ApplicationFiled: September 30, 2016Publication date: January 19, 2017Applicant: Mallinckrodt Hospital Products IP LimitedInventors: Craig R. Tolmie, Jeff Milsap, Jaron M. Acker
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Publication number: 20160367775Abstract: Described are systems and methods for compensating long term sensitivity drift of catalytic type electrochemical gas sensors used in systems for delivering therapeutic nitric oxide (NO) gas to a patient by compensating for drift that may be specific to the sensors atypical use in systems for delivering therapeutic nitric oxide gas to a patient. In at least some instances, the long term sensitivity drift of catalytic type electrochemical gas sensors can be addressed using calibration schedules, which can factor in the absolute change in set dose of NO being delivered to the patient that can drive one or more baseline calibrations. The calibration schedules can be used reduce the amount of times the sensor goes offline. Systems and methods described may factor in in actions occurring at the delivery system and/or aspects of the surrounding environment, prior to performing a baseline calibration, and may postpone the calibration and/or rejected using the sensor's output for the calibration.Type: ApplicationFiled: September 2, 2016Publication date: December 22, 2016Applicant: Mallinckrodt Hospital Products IP LimitedInventors: Craig R. Tolmie, Jeff Milsap, Jaron M. Acker
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Publication number: 20160310693Abstract: A nitric oxide delivery device including a valve assembly, a control module and a gas delivery mechanism is described. An exemplary gas delivery device includes a valve assembly with a valve and circuit including a memory, a processor and a transceiver in communication with the memory. The memory may include gas data such as gas identification, gas expiration and gas concentration. The transceiver on the circuit of the valve assembly may send wireless optical line-of-sight signals to communicate the gas data to a control module. Exemplary gas delivery mechanisms include a ventilator and a breathing circuit. Methods of administering gases containing nitric oxide are also described.Type: ApplicationFiled: July 7, 2016Publication date: October 27, 2016Applicant: MALLINCKRODT HOSPITAL PRODUCTS IP LIMITEDInventors: Duncan P. Bathe, John Klaus, David Christensen
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Patent number: 9408993Abstract: A nitric oxide delivery device including a valve assembly, a control module and a gas delivery mechanism is described. An exemplary gas delivery device includes a valve assembly with a valve and circuit including a memory, a processor and a transceiver in communication with the memory. The memory may include gas data such as gas identification, gas expiration and gas concentration. The transceiver on the circuit of the valve assembly may send wireless optical line-of-sight signals to communicate the gas data to a control module. Exemplary gas delivery mechanisms include a ventilator and a breathing circuit. Methods of administering gases containing nitric oxide are also described.Type: GrantFiled: July 10, 2014Date of Patent: August 9, 2016Assignee: Mallinckrodt Hospital Products IP LimitedInventors: Duncan P. Bathe, John Klaus, David Christensen
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Patent number: 9381212Abstract: The present invention provides a treatment of acute respiratory distress syndrome (ARDS) in children using dosing of nitric oxide at low concentrations, such as less than 10 ppm.Type: GrantFiled: January 9, 2015Date of Patent: July 5, 2016Assignee: Mallinckrodt Hospital Products IP LimitedInventors: Jim Potenziano, Ronald Bronicki, James Baldassarre
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Patent number: 9351994Abstract: Described are methods and systems for delivering a pharmaceutical gas to a patient. The methods and systems provide varying quantities of pharmaceutical gas delivered to the patient in two or more breaths based on the monitored respiratory rate or changes in the patient's respiratory rate.Type: GrantFiled: February 27, 2013Date of Patent: May 31, 2016Assignee: Mallinckrodt Hospital Products IP LimitedInventors: Frederick J. Montgomery, Duncan P. Bathe
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Patent number: 9295802Abstract: A gas delivery system including a gas delivery device, a control module and a gas delivery mechanism is described. An exemplary gas delivery device includes a valve assembly with a valve and circuit including a memory, a processor and a transceiver in communication with the memory. The memory may include gas data such as gas identification, gas expiration and gas concentration. The transceiver on the circuit of the valve assembly may send wireless optical line-of-sight signals to communicate the gas data to a control module. Exemplary gas delivery mechanisms include a ventilator and a breathing circuit. Methods of administering gas are also described.Type: GrantFiled: February 24, 2015Date of Patent: March 29, 2016Assignee: Mallinckrodt Hospital Products IP LimitedInventors: Duncan P. Bathe, John Klaus, David Christensen
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Patent number: D776278Type: GrantFiled: October 30, 2015Date of Patent: January 10, 2017Assignee: MALLINCKRODT HOSPITAL PRODUCTS IP LIMITEDInventors: David Newman, Patrick Sharpe, David Strait
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Patent number: D776279Type: GrantFiled: October 30, 2015Date of Patent: January 10, 2017Assignee: MALLINCKRODT HOSPITAL PRODUCTS IP LIMITEDInventors: David Newman, Brian Paap, Patrick Sharpe, David Strait