Abstract: Systems and methods for tracking dosage periods are disclosed. The systems and methods may include setting a timer (140) to a predetermined value corresponding to a dosage period in response to the engagement of a cover (110) to a container (120). An indication may be provided that corresponds to a remaining period in the dosage period set by the engagement of the cover (110) and container (120). The indication may also indicate a remaining time period in the dosage period.

Abstract: In one characterization, the present invention relates to a radiation-shielding assembly for holding a container having a radioactive material disposed therein. The assembly may, at least in one regard, be referred to as an elution shield and/or a dispensing shield. The assembly includes a body at least partially defining a cavity. There is at least one opening through the body into the cavity. The assembly may include a cap that at least generally hinders escape of radiation from the assembly through the opening. The cap may be releasably attached to the body in one orientation and may establish non-attached engagement with the body in another orientation. The assembly may include an adjustable spacer system for adapting the assembly for use with containers having different heights.

Abstract: In one characterization, the present invention relates to a radiation-shielding assembly for holding a container having a radioactive material disposed therein. The assembly may, at least in one regard, be referred to as an elution shield and/or a dispensing shield. The assembly includes a body at least partially defining a cavity. There is at least one opening through the body into the cavity. The assembly may include a cap that at least generally hinders escape of radiation from the assembly through the opening. The cap may be releasably attached to the body in one orientation and may establish non-attached engagement with the body in another orientation. The assembly may include an adjustable spacer system for adapting the assembly for use with containers having different heights.

Abstract: Embodiments of the present invention include systems and methods that relate to pulse oximetry. Specifically, one embodiment includes an oximeter sensor, comprising a light emitting element configured to emit light, a light detector configured to receive the light, and a pressure switch that is sensitive to pressure present due to placement of the sensor on a patient, the pressure switch having a status indicative of sensor contact with the patient.

Abstract: Processes are described for the synthesis of 3-hydroxymorphinan derivatives by hydrolysis of side products from the O-demethylation of 3-methoxymorphinan derivatives.

Abstract: Embodiments of the present invention include systems and methods that relate to pulse oximetry. Specifically, one embodiment includes an oximeter sensor comprising a light emitting element configured to emit light, a light detector configured to detect the light, and a memory storing an optical shunting measurement for the oximeter sensor.

Abstract: A syringe for an injector that has at its nozzle end a connection to the fluid delivery tubing that prevents, reduces, or eliminates fluid leaks, by virtue of a ridge on the external surfaces of the connector which engage to tubing. Furthermore, the syringe and injector are configured to permit the syringe to be oriented in more than one manner on the injector.

Abstract: The present invention is directed to the conversion of a 6-keto morphinan to a 6-alpha-hydroxy morphinan in the presence of a ruthenium, rhodium, or iridium asymmetric catalyst and a hydrogen source.

Abstract: Embodiments of the present invention include systems and methods that relate to pulse oximetry. Specifically, one embodiment includes an oximeter sensor comprising a light emitting element configured to emit light, a light detector configured to detect the light a memory storing data, and a changeable encryption key to facilitate scrambling the data to make the data inaccessible to devices that are without an appropriate decryption mechanism.

Abstract: The present invention relates to management of information relating to medical fluids, containers therefor, and medical fluid administration devices for administering such medical fluids to patients. Data tags (e.g., RFID tags) are generally associated with containers of the invention and may be electromagnetically read from and/or written to using an electromagnetic device, for example, that may be associated with a medical fluid administration device of the invention.

Abstract: The present invention relates to management of information relating to medical fluids, containers therefor, and medical fluid administration devices for administering such medical fluids to patients. Data tags (e.g., RFID tags) are generally associated with containers of the invention and may be electromagnetically read from and/or written to using an electromagnetic device, for example, that may be associated with a medical fluid administration device of the invention.

Abstract: A power injector (302) with syringe communication logic (316) is disclosed. A communication with a syringe (320) for the power injector (302) may be initiated via data provided by one or more of a tilt sensor (306), a syringe clamp sensor (308), a prefilled syringe sensor (310), or an imaging energy output sensor (312).

Abstract: A power injector (302) with syringe communication logic (316) is disclosed. A communication with a syringe (320) for the power injector (302) may be initiated via data provided by one or more of a tilt sensor (306), a syringe clamp sensor (308), a prefilled syringe sensor (310), or an imaging energy output sensor (312).

Abstract: The present invention provides (+)-morphinans comprising Toll-like receptor 9 (TLR9) antagonist activity, as well as methods for using the (+)-morphinans to treat pain. Also provided are pharmaceutical combination compositions comprising a (+)-morphinan and an opioid agonist/monoamine reuptake inhibitor, as well as methods for using the combination compositions to treat pain.

Abstract: Embodiments of the present invention include systems and methods that relate to pulse oximetry. Specifically, one embodiment includes an oximeter sensor comprising a light emitting element configured to emit light, a light detector configured to receive the light, and an accelerometer configured to detect motion of the oximeter sensor.

Abstract: A method of performing cardiac surgery on a patient's heart, including covering a patient with an inflatable blanket for a forced air convection system, the inflatable blanket having at least one separable seal line within the blanket. The separable seal line may be separated to form a slit. A patient's femoral artery is accessed through the slit, and an elongate medical instrument is passed through the slit, and through the femoral artery toward the patient's heart. Cardiac surgery is performed with the elongate medical instrument, and the elongate medical instrument is withdrawn from the femoral artery through the slit.

Abstract: Embodiments of the present invention include systems and methods that relate to a sensor with memory. Specifically, one embodiment includes a sensor, comprising a light emitting element configured to emit light, a light detecting element configured to detect the light, and a memory storing data corresponding to algorithms used by an oximeter monitor, the memory providing access to the oximeter monitor to read the data.

Abstract: A process for the purification of an impure preparation containing naltrexone by means of a reverse phase preparative chromatography process is provided. In an illustrative embodiment a chromatographic column is loaded with a stationary phase, typically a silica particle having an organic ligand bound thereto. With a loading ratio of from about 10 to about 1000 the impure preparation is acidified and passed through the column. The column is eluted with typically an aqueous solution with acetonitrile and the purified naltrexone is obtained in a specified fraction.

Abstract: A pharmaceutical pig is used to transport a syringe containing a liquid radiopharmaceutical from a radiopharmacy to a medical facility for administration to a patient. The pharmaceutical pig includes an elongate polymer cap that is removably attached to an elongate polymer base. The elongate polymer cap includes a cap shell that completely encloses a cap shielding element and the elongate polymer base includes a base shell that completely encloses a base shielding element. Preferably the polymer utilized for the cap shell and the base shell is polycarbonate resin, e.g., LEXAN®. An inner liner is not utilized and the cap shielding element and the base shielding element, which are preferably, but not necessarily, made of lead, are completely sealed and unexposed.

Abstract: A pharmaceutical pig is used to transport a syringe containing a liquid radiopharmaceutical from a radiopharmacy to a medical facility for administration to a patient. The pharmaceutical pig includes an elongate polymer cap that is removably attached to an elongate polymer base. The elongate polymer cap includes a cap shell that completely encloses a cap shielding element and the elongate polymer base includes a base shell that completely encloses a base shielding element. Preferably the polymer utilized for the cap shell and the base shell is polycarbonate resin, e.g., LEXAN®. An inner liner is not utilized and the cap shielding element and the base shielding element, which are preferably, but not necessarily, made of lead, are completely sealed and unexposed.