Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.
Type:
Grant
Filed:
December 18, 2015
Date of Patent:
October 17, 2017
Assignees:
The Broad Institute Inc., Massachusetts Institude of Technology, President and Fellows of Harvard College
Inventors:
Feng Zhang, Bernd Zetsche, Ian Slaymaker, Jonathan Gootenberg, Omar O. Abudayyeh