Abstract: An interactive system is provided with at least one active surface of plastic from monomers containing at least one structural element derived from a carbon dioxide (A), and at least one substance associated to a linker with at least one structural element (B) capable of establishing a hydrogen bond, and involving an interaction between the structural elements (A) and (B). The interactive system is suitable for presenting and eliminating substances in liquids.

Abstract: The invention relates to a method and a device for detection of splice sites in DNA or RNA sequences comprising three steps: a) examining a training set of sequences comprising DNA or RNA sequences with known splice sites by an automated, discriminative training device for detecting splicing patterns, especially in a predetermined window around the known splice sites; b) scanning a sequence comprising DNA or RNA sequences containing unknown splice sites for the occurrence of the splicing patterns detected in step a); and c) calculation of a cumulative splice score in dependence of a maximization of the margin between the true splice forms and all wrong splice forms in the sequence. The invention also relates to a method and a device for detection of splice forms and alternative splice forms in DNA or RNA sequences.

Abstract: The present invention relates to an interactive system comprising at least one active surface of plastic from monomers containing at least one structural element derived from a carbon dioxide (A), and at least one substance associated to a linker with at least one structural element (B) capable of establishing a hydrogen bond, and involving an interaction between the structural elements (A) and (B). That interactive system is suitable for presenting and eliminating substances in liquids.

Abstract: This invention relates to the use of an inhibitor of an activatable metabolic enzyme, which inhibitor is bound to a high molecular weight carrier, as a molecular marker for determining the activation of this enzyme for the diagnosis of the enzyme. The invention relates in particular to the use of a thrombin inhibitor, which is bound to a high molecular weight carrier, as a molecular marker for determining clotting activation in clotting diagnosis and therapy monitoring. The invention preferably relates to the use of dextran-hirudin or PEG-coupled hirudin as a molecular marker for clotting diagnosis and therapy monitoring.

Abstract: The invention concerns an adenovirus vector for liver specific gene thera fields of application in medicine are the treatment of gene defects and tumour diseases of the liver and molecular biology. The vector according to the invention is marked by the fact that a therapeutic gene is coupled with a liver-specific promoter consisting of enhancer elements of the hepatitis B virus and an enhancerless minimum promoter and is optionally surrounded by SAR elements wherein the promoter is inserted into the adenovirus genome.

Abstract: Apparatus for the production of short-wave electromagnetic radiaion, especially in the x-ray and gamma-ray region, by means of the interaction between accelerated charged particles, especially electrons or positrons, and a crystal lattice, with a charged-particle source for the production of a beam of energetic charged particles and with a crystal arrangement which is so arranged in the path of the charged particle radiation beam that the charged particles traverse the crystal lattice of the crystal arrangement parallel to a predetermined lattice direction ("channeling-condition"). In order to produce an electromagnetic radiation beam with predetermined convergence or divergence, there are used a correspondingly convergent or divergent charged particle radiation beam (212) as well as a crystal arrangement (214) which is so bent that the channeling condition is at least approximately fulfilled for all charged particle paths in the crystal. (FIG.