Patents Assigned to MBC Research, Inc.
  • Biphosphonate conjugates and methods of making and using the same
    Patent number: 6896871
    Abstract: The present invention is directed to particular bisphosphonate compounds, and in particular, to bisphosphonate conjugates that are useful in the treatment of soft tissues surrounding bone and bone-related diseases, such as bone cancer and osteoporosis.
    Type: Grant
    Filed: April 10, 2001
    Date of Patent: May 24, 2005
    Assignee: MBC Research, Inc.
    Inventors: Alexander Karpeisky, Nelly Padioukova, Sergey Mikhailov, H.B.F. Dixon, Grigorii Tzeitline, Marat Karpeisky
  • Bisphosphonate conjugates and methods of making and using the same
    Patent number: 6750340
    Abstract: The present invention is directed to particular bisphosphonate compounds, and in particular, to bisphosphonate conjugates that are useful in the treatment of soft tissues surrounding bone and bone-related diseases, such as bone cancer and osteoporosis.
    Type: Grant
    Filed: December 7, 2000
    Date of Patent: June 15, 2004
    Assignee: MBC Research, Inc.
    Inventors: Nelly Padioukova, Sergey Mikhailov, H. B. F. Dixon, Grigorii Tzeitline
  • Bisphosphonate conjugates and methods of making and using the same
    Patent number: 6214812
    Abstract: Bisphosphonate conjugates capable of releasing antibacterial and/or cytotoxic components upon binding with bone tissue. Such conjugates are useful in the treatment and prevention of bone cancer, bone infections and other bone-related diseases. Bisphosphonate conjugates are also delivery vehicles for use in delivering pharmaceutical compositions to bone tissue. Methods of synthesizing novel bisphosphonates and pharmaceutical compositions incorporating the same, and medical uses for such compositions, are provided. Compositions of the present invention include bone-seeking radio isotope conjugates for use in imaging and therapy.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: April 10, 2001
    Assignee: MBC Research, Inc.
    Inventors: Marat Karpeisky, Nelly Padioukova, Sergey Mikhailov, H. B. F. Dixon, Grigorii Tzeitline