Abstract: An apparatus includes a generator including a control module that is operably coupled to a power module. The power module is configured to produce an electronic signal to be received by an ultrasonic energy delivery assembly. The ultrasonic energy delivery assembly is characterized by a natural frequency, and the electronic signal is characterized by a frequency. The control module is configured to send a control signal to the power module to randomly vary the frequency of the electronic signal within a range defined at least in part by the natural frequency.

Abstract: An apparatus includes a transmission member having a proximal end portion and a distal end portion. The transmission member is configured to be inserted into a bodily lumen, and is configured to transfer ultrasonic energy from the proximal end portion to the distal end portion. The transmission member defines a lumen along a longitudinal center line of the transmission member. The distal end portion of the transmission member includes a concave engagement surface and a distal end surface. The distal end surface defines a plane that intersects the longitudinal center line of the transmission member at an angle of between about 75 degrees and about 105 degrees. The engagement surface is configured to engage a target tissue within the bodily lumen to limit movement of the target tissue along the longitudinal center line. The engagement surface defines an opening in fluid communication with the lumen.

Abstract: An apparatus includes a monolithically-constructed transmission member that defines a lumen along a longitudinal axis. The transmission member includes a first portion, a second portion, and a third portion. The first portion is configured to be coupled to an ultrasonic energy source. The second portion is configured to contact a bodily tissue to transfer ultrasonic energy from a first portion into the bodily tissue. The third portion is disposed between the first portion and the second portion and defines a cross-sectional moment of inertia that is less than at least one of a cross-sectional area moment of inertia of the first portion or a cross-sectional moment of inertia of the second portion.

Abstract: An apparatus includes a generator including a control module that is operably coupled to a power module. The power module is configured to produce an electronic signal to be received by an ultrasonic energy delivery assembly. The ultrasonic energy delivery assembly is characterized by a natural frequency, and the electronic signal is characterized by a frequency. The control module is configured to send a control signal to the power module to randomly vary the frequency of the electronic signal within a range defined at least in part by the natural frequency.

Abstract: An apparatus includes a generator including a control module that is operably coupled to a power module. The power module is configured to produce an electronic signal to be received by an ultrasonic energy delivery assembly. The ultrasonic energy delivery assembly is characterized by a natural frequency, and the electronic signal is characterized by a frequency. The control module is configured to send a control signal to the power module to randomly vary the frequency of the electronic signal within a range defined at least in part by the natural frequency.

Abstract: An apparatus includes a generator including a control module that is operably coupled to a power module. The power module is configured to produce an electronic signal to be received by an ultrasonic energy delivery assembly. The ultrasonic energy delivery assembly is characterized by a natural frequency, and the electronic signal is characterized by a frequency. The control module is configured to send a control signal to the power module to randomly vary the frequency of the electronic signal within a range defined at least in part by the natural frequency.

Abstract: An apparatus includes a monolithically-constructed transmission member that defines a lumen along a longitudinal axis. The transmission member includes a first portion, a second portion, and a third portion. The first portion is configured to be coupled to an ultrasonic energy source. The second portion is configured to contact a bodily tissue to transfer ultrasonic energy from a first portion into the bodily tissue. The third portion is disposed between the first portion and the second portion and defines a cross-sectional moment of inertia that is less than at least one of a cross-sectional area moment of inertia of the first portion or a cross-sectional moment of inertia of the second portion.

Abstract: An apparatus includes a monolithically-constructed transmission member that defines a lumen along a longitudinal axis. The transmission member includes a first portion, a second portion, and a third portion. The first portion is configured to be coupled to an ultrasonic energy source. The second portion is configured to contact a bodily tissue to transfer ultrasonic energy from a first portion into the bodily tissue. The third portion is disposed between the first portion and the second portion and defines a cross-sectional moment of inertia that is less than at least one of a cross-sectional area moment of inertia of the first portion or a cross-sectional moment of inertia of the second portion.

Abstract: A coupler includes a first portion and a second portion, and defines a passageway configured to fixedly receive a proximal end portion of a transmission member. The first portion is configured to be coupled to an ultrasonic energy source. The coupler is configured to transfer at least a portion of an ultrasonic vibration produced by the ultrasonic energy source to the transmission member. Furthermore, the first portion and the second portion are collectively configured to adjust a resonant frequency of the transmission member to correspond to a vibrational frequency of the ultrasonic vibration produced by the ultrasonic energy source. In some embodiments, the portion of the ultrasonic vibration includes a linear component. In such embodiments, the first portion and the second portion are collectively configured to transform at least a portion of the linear component of the ultrasonic vibration into a torsional component within the transmission member.

Abstract: An apparatus includes a generator including a control module that is operably coupled to a power module. The power module is configured to produce an electronic signal to be received by an ultrasonic energy delivery assembly. The ultrasonic energy delivery assembly is characterized by a natural frequency, and the electronic signal is characterized by a frequency. The control module is configured to send a control signal to the power module to randomly vary the frequency of the electronic signal within a range defined at least in part by the natural frequency.

Abstract: An apparatus includes a monolithically-constructed transmission member that defines a lumen along a longitudinal axis. The transmission member includes a first portion, a second portion, and a third portion. The first portion is configured to be coupled to an ultrasonic energy source. The second portion is configured to contact a bodily tissue to transfer ultrasonic energy from a first portion into the bodily tissue. The third portion is disposed between the first portion and the second portion and defines a cross-sectional moment of inertia that is less than at least one of a cross-sectional area moment of inertia of the first portion or a cross-sectional moment of inertia of the second portion.