Abstract: A device (10) for delivery of glucose-regulating medication depending on the measured tissue glucose concentration, having a sensor (7) for measuring the glucose concentration in the tissue fluid, possibly a unit (1) for removing fluid from subcutaneous tissue (11), as well as a container (14) for the medications, having a unit (23) for subcutaneous delivery of the glucose-regulating medications, and having a unit (12) connected to the glucose sensor (7) for regulating the delivery of the glucose-regulating medication depending on the measured tissue glucose concentrations. To provide a device (10) simulating the function of the natural pancreas and being compact, the sensor (7) for measuring the tissue glucose concentration or the unit (1) for removing the tissue fluid is combined with the delivery unit (23), particularly in a shared catheter (25), so that the measurement of the tissue glucose concentration is essentially performed at the location of the delivery of the glucose-regulating medication.

Abstract: The invention relates to a device (5) for delivery of substances (9) to and removal of bodily substances (22) from a tissue (2) or vessel (25) of a body using an element (6) to be positioned in the tissue (2) or vessel (25).