Abstract: A model of flow through a left ventricular assist device (LVAD) can be used for preoperative planning of implantation of the LVAD into a patient and/or optimization of the LVAD after implantation into the patient are described. At least one imaging data set related to a patient and at least one physiological data set related to the patient can be received. An ideal parameter related to the LVAD can be determined based on the at least one imaging data set related to the patient, the at least one physiological data set related to the patient using a model of circulation in a large spatial region of the patient's body and a three-dimensional anatomical model of at least one component of the region of the patient's body and at least one component of the LVAD. Flow patterns within the three-dimensional anatomical model are calculated using computational fluid dynamics.

Abstract: An obscuring cover for covering at least a portion of a saw that includes a saw body and a saw blade attached to the saw body is provided. The obscuring cover includes an interior cavity defined by at least one inner surface of the obscuring cover. The interior cavity is configured to removably receive at least a portion of the saw body. At least one securing member is at least partially located at least one of internal to and adjacent to the interior cavity. The at least one securing member is configured to removably engage an exterior portion of the saw to removably connect the obscuring cover to the saw. At least a portion of the obscuring cover is configured to at least partially visually obstruct a subject's view of the saw blade when the obscuring cover is connected to the saw.

Abstract: Vaginal dilator assemblies, devices and kits. Assemblies can include a base, and an adapter. The base can have an inner portion and the adapter can have an outer portion that is complimentary to the inner portion of the base such that the adapter is non-rotatably fitted into the base. Vaginal dilator devices can include a base defining a recess aligned with the longitudinal axis of the base. The recess can have a plurality of step tapered sections. Vaginal dilator kits are also provided that include a plurality of vaginal dilators having different diameters. Each of the plurality of vaginal dilators is configured to be axially aligned and securely fitted into one of the step tapered sections of the recess of the base.

Abstract: Compositions comprising bile acids or their salts and methods of use thereof for the treatment of residual lesions of vascular anomalies.

Abstract: The invention relates to methods for treating COVID-19 by targeting the inflammasome/caspase1/pyroptosis axis as a key inflammatory pathway. In particular, the invention relates to treating a patient infected with SARS-CoV-2 with an effective amount of one or more compounds that directly or indirectly inhibit one or more pathways of the inflammasome/caspase1/pyroptosis axis.

Abstract: An apparatus for helping to protect a patient's hair is provided. The apparatus includes a sheet configured to cover a patient's hair during an operation. A sealing member is provided on or joined to a leading end of the sheet. The sealing member is configured to be applied to a patient's skin adjacent to an operating field to create a seal between the operating field and the patient's hair. At least one anchoring member is joined to the sheet adjacent to the leading end of the sheet. The at least one anchoring member is configured to be attached to the patient's hair adjacent to the operating field to anchor the apparatus to the patient.

Abstract: Compositions comprising bile acids or their salts and methods of use thereof for the treatment of residual lesions of vascular anomalies.

Abstract: A bra is disclosed comprising a body portion and left and right adjustable shoulder straps. The body portion comprises a back panel, left and right front panels, an adjustable torso strap, and a releasable front closure. The left and right front panels comprise cups having an interior mesh lining over at least a portion of each cup. The mesh lining forms a pocket with each cup and has a coating comprising an antibacterial, antimicrobial agent. The adjustable torso strap comprises a back torso strap, left and right front torso straps, and left and right side torso straps. The left and right side torso straps have end portions that are removably attachable to left and right front torso straps. When attached to the left and right front torso straps, the left and right side torso straps and left and right front panels define left and right drainage ports.

Abstract: A bra is disclosed comprising a body portion and left and right adjustable shoulder straps. The body portion comprises a back panel, left and right front panels, an adjustable torso strap, and a releasable front closure. The left and right front panels comprise cups having an interior mesh lining over at least a portion of each cup. The mesh lining forms a pocket with each cup and has a coating comprising an antibacterial, antimicrobial agent. The adjustable torso strap comprises a back torso strap, left and right front torso straps, and left and right side torso straps. The left and right side torso straps have end portions that are removably attachable to left and right front torso straps. When attached to the left and right front torso straps, the left and right side torso straps and left and right front panels define left and right drainage ports.

Abstract: One aspect of the present disclosure relates to a physical training system for injury prevention and rehabilitation. The training system can include a wearable device in communication with an external device, which can be used to train at least the athlete wearing the wearable device. The wearable device can reduce the number of sensors needed to capture motion data required for the training. For example, the wearable device can include an inertial measurement unit (IMU) device located at a position relative to a joint of an athlete to measure an inertial displacement of the joint and an optical sensor to measure an angle of the joint. The wearable device can include a wireless transceiver to communicate a characteristic of motion of the joint (determined based on data from the IMU and the optical sensor) to an external device.

Abstract: An embolization scaffold device. The scaffold has a base having a central longitudinal axis extending therethrough and a plurality of expandable struts extending from the base. Each of the struts has a proximal portion extending from the base and substantially aligned with the central longitudinal axis, an intermediate arcuate portion radially extending away from the central longitudinal axis, and a distal portion curving back towards the central longitudinal axis.

Abstract: Systems and methods are provided for an electrocardiograph system. A set of electrodes is configured to detect a voltage differences between various pairs of locations on a body of a patient. A display is configured to visually represent digital signals derived from the plurality of detected voltage differences. A display interface is configured to format the digital signals for the display, such that the leads are grouped and displayed as a sequence of proper subsets or groups of the plurality of detected voltage differences. Each proper subset or lead group represents a specific anatomical structure of a heart of the patient.

Abstract: Compositions comprising bile acids or their salts and methods of use thereof for the treatment of residual lesions of vascular anomalies.

Abstract: A non-invasive system, and method for simple, quantitative screening for mTBI and other forms of mid cognitive impairment using a visuo-motor performance test (for example, a submaximal grip test) in response to visual feedback to quantitatively measure the intra-individual variability of performance metric for initial screening of patients with mild traumatic brain injury (mTBI), and other neurological disorders. The system and method can be administered in minutes, by any level of caregiver, in any environment including military in-the-field or sports on-field deployments, and is useful in screening those truly injured from those disguising or mimicking injury. In addition to screening, the system and method can be used to monitor and/or detect changes to intra-individual variability over time by comparison to a baseline, which in turn is helpful in determining estimated recovery trajectory or other related information.

Abstract: A tendon repair apparatus includes a tendon bridge having oppositely disposed proximal and distal bridge ends spaced longitudinally apart by a bridge body. A plurality of engagement legs is provided. Each engagement leg has a proximal leg end attached directly to a corresponding one of the proximal and distal bridge ends and a distal leg end spaced transversely apart from the tendon bridge. At least one receiver plate, transversely spaced from the tendon bridge and extending substantially longitudinally and laterally parallel to the tendon bridge, is provided. The receiver plate includes a plurality of receiver apertures. Each receiver aperture corresponds to a selected engagement leg. Each receiver aperture is configured to selectively engage with a corresponding selected engagement leg. Engagement between the receiver aperture and the engagement leg maintains the receiver plate in transversely spaced indirect connection with the tendon bridge.

Abstract: One aspect of the present disclosure describes a method for burn wound assessment that identifies burn wound conversion. The method includes performing non-contact imaging on the burn wound with an imaging modality configured to record imaging data. The imaging modality includes active dynamic thermography (ADT). Based on the imaging data, an area of the burn wound undergoing conversion can be determined. The determination can be accomplished automatically by a system comprising a processor.

Abstract: Systems and methods for eye tracking include a video capture component that provides a video of an environment and a set of gaze tracking coordinates for the video. A library stores a plurality of feature sets representing respective areas of interest with respective object labels. An image annotation component extracts a plurality of features from a region of interest and matches the extracted features to an area of interest in the library to produce a selected area of interest and a confidence value. A verification component accepts the selected area of interest if the confidence value meets a threshold value and sends the region of interest to a human expert to assign an object label if the confidence value does not. The library is dynamically updated in response to input from the human expert to add new areas of interest and new object labels to the library.

Abstract: A method of diagnosing and selecting treatment for a urinary tract infection (UTI) in a subject having a neuropathic bladder (NB) is described. The method includes screening the subject for UTI risk; selecting a proper lower urinary symptom or UTI treatment if the determined risk exceeds a threshold, wherein the proper treatment is the administration of a therapeutically effective amount of a probiotic treatment to the subject and treating the subject.