Abstract: The present invention relates to new transcriptional promoters that are functional during meiosis. It thus provides new tools, methods and compositions for the expression of proteins during meiosis in a eukaryotic cell, and more particularly in a plant cell.
Type:
Grant
Filed:
May 23, 2019
Date of Patent:
October 24, 2023
Assignees:
MEIOGENIX, INTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NORMALE SUPERIEURE DE LYON
Inventors:
Giacomo Bastianelli, Alain Nicolas, Peter Rogowsky
Abstract: The present invention relates to a fusion protein comprising a Cas9 domain and a Spo11 domain, as well as the use of this protein to induce targeted meiotic recombinations in a eukaryotic cell.
Type:
Grant
Filed:
January 29, 2016
Date of Patent:
February 15, 2022
Assignees:
MEIOGENIX, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITE
Inventors:
Giacomo Bastianelli, Alexandre Serero, Alain Nicolas
Abstract: The present invention relates to a fusion protein comprising a Cas9 domain and a Spo11 domain, as well as the use of this protein to induce targeted meiotic recombinations in a eukaryotic cell.
Type:
Application
Filed:
January 29, 2016
Publication date:
January 25, 2018
Applicants:
MEIOGENIX, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
Inventors:
GIACOMO BASTIANELLI, ALEXANDRE SERERO, ALAIN NICOLAS