Patents Assigned to Memorial Sloane Kittering Cancer Center - Justia Patents Search

Patents Assigned to Memorial Sloane Kittering Cancer Center

Monoclonal antibody specific for vascular endothelial cell antigen endoglyx-1 and uses thereof for detection of, and isolation of, vascular endothelial cells

Patent number: 5536641

Abstract: An antigen which is specific to vascular endothelium is described. Described is a cell surface antigen which consists of four subunits, of 190, 145, 125 and 110 kd as determined by SDS-PAGE under reducing conditions as is a monoclonal antibody specific to this antigen. Uses, both diagnostic and therapeutic, are also described.

Type: Grant

Filed: May 17, 1994

Date of Patent: July 16, 1996

Assignee: Memorial Sloane Kittering Cancer Center

Inventors: Maria P. Sanz-Moncasi, Pilar Garin-Chesa, Elisabeth Stockert, Lloyd J. Old, Wolfgang J. Rettig