Abstract: Novel quinazolinamide derivatives of the formula (I), in which R1-R5 and X have the meanings indicated in Claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.
Type:
Application
Filed:
November 12, 2009
Publication date:
October 6, 2011
Applicant:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING
Inventors:
Hans-Michael Eggenweiler, Christian Sirrenberg, Hans-Peter Buchstaller
Abstract: The invention relates to a process for preparing an electronic device using a protection layer, and to improved electronic devices prepared by this process, in particular organic field effect transistors (OFETs).
Type:
Application
Filed:
March 28, 2008
Publication date:
May 6, 2010
Applicant:
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING
Inventors:
David Christoph Mueller, Toby Cull, Simon Dominic Ogier
Abstract: Arylbenzoylguanidines of the formula I ##STR1## in which R.sup.1 R.sup.2, R.sup.3 and Ph have the given meanings herein, and also the physiologically harmless salts thereof, exhibit antiarrhythmic properties and act as inhibitors of the cellular Na.sup.+ /H.sup.+ antiporter.
Type:
Grant
Filed:
August 25, 1995
Date of Patent:
September 15, 1998
Assignee:
Merck Patent Gesellschaft mit Beschrankter Hafting