Abstract: Provided herein are methods for preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Type:
Grant
Filed:
July 28, 2015
Date of Patent:
August 16, 2022
Assignees:
The Regents of the University of California, Meritage Pharma, Inc.
Inventors:
Ranjan Dohil, John Bastian, Seema S. Aceves, Elaine Phillips, Malcolm Hill
Abstract: Provided herein are methods for preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Type:
Grant
Filed:
March 11, 2019
Date of Patent:
December 14, 2021
Assignees:
The Regents of the University of California, Meritage Pharma, Inc.
Inventors:
Ranjan Dohil, John Bastian, Seema Aceves, Elaine Phillips, Malcolm Hill
Abstract: Provided herein are methods for treating, preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Abstract: The invention relates to pharmaceutical compositions comprising a corticosteroid and an antioxidant. The invention further relates to methods of treating, preventing, or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract comprising administering the pharmaceutical compositions comprising a corticosteroid and an antioxidant.
Abstract: Provided herein are methods for treating, preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Abstract: Provided herein are methods for preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Type:
Grant
Filed:
September 18, 2017
Date of Patent:
April 30, 2019
Assignees:
The Regents of the University of California, Meritage Pharma, Inc.
Inventors:
Ranjan Dohil, John Bastian, Seema Aceves, Elaine Phillips, Malcolm Hill
Abstract: Provided herein are computer-based systems, software, and methods of using the same including a daily patient questionnaire, the questionnaire comprising: a question for determining whether the patient avoided solid food; a question for determining whether the patient had difficulty swallowing solid food; a question for determining what action the patient took to correct or relieve difficulty swallowing food; a question for determining the amount of pain the patient experienced while swallowing food; and a software module configured to apply an algorithm to answers to one or more of said questions to determine a score, wherein said score illustrates one or more selected from the group consisting of: (1) severity, intensity, or frequency of patient dysphagia; (2) suitability of a patient for a particular diagnostic tool, diagnostic method, or therapy for dysphagia; and (3) efficacy of a particular therapy for dysphagia.
Type:
Grant
Filed:
September 11, 2015
Date of Patent:
January 8, 2019
Assignee:
MERITAGE PHARMA, INC.
Inventors:
Malcolm Hill, Robert Farber, Bonnie Hepburn, Linda Gieschen
Abstract: Provided herein are methods for treating the symptoms of and inflammation associated with gastroesophageal reflux disease (GERD) and other conditions. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Abstract: Provided herein are methods for preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Type:
Grant
Filed:
January 3, 2014
Date of Patent:
October 10, 2017
Assignees:
The Regents of the University of California, Meritage Pharma, Inc.
Inventors:
Ranjan Dohil, John Bastian, Seema Aceves, Elaine Phillips, Malcolm Hill
Abstract: Provided herein are methods for treating the symptoms of and inflammation associated with gastroesophageal reflux disease (GERD) and other conditions. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Abstract: Provided herein are computer-based systems, software, and methods of using the same including a daily patient questionnaire, the questionnaire comprising: a question for determining whether the patient avoided solid food; a question for determining whether the patient had difficulty swallowing solid food; a question for determining what action the patient took to correct or relieve difficulty swallowing food; a question for determining the amount of pain the patient experienced while swallowing food; and a software module configured to apply an algorithm to answers to one or more of said questions to determine a score, wherein said score illustrates one or more selected from the group consisting of: (1) severity, intensity, or frequency of patient dysphagia; (2) suitability of a patient for a particular diagnostic tool, diagnostic method, or therapy for dysphagia; and (3) efficacy of a particular therapy for dysphagia.
Type:
Application
Filed:
September 11, 2015
Publication date:
March 17, 2016
Applicant:
MERITAGE PHARMA INC.
Inventors:
Malcolm Hill, Robert Farber, Bonnie Hepburn, Linda Gieschen
Abstract: Provided herein are methods for treating, preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Type:
Grant
Filed:
November 12, 2008
Date of Patent:
June 9, 2015
Assignee:
Meritage Pharma, Inc.
Inventors:
Elaine Phillips, Malcolm Hill, Hemant Deshmukh, Keith Johnson, Cynthia Licalsi
Abstract: Provided herein are methods for treating, preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Abstract: Provided herein are methods for preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Type:
Application
Filed:
January 3, 2014
Publication date:
July 3, 2014
Applicants:
Meritage Pharma, Inc., The Regents of the University of California
Inventors:
Ranjan Dohil, John Bastian, Seema Aceves, Elaine Phillips, Malcolm Hill
Abstract: Provided herein are methods for preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Type:
Grant
Filed:
November 12, 2008
Date of Patent:
March 25, 2014
Assignees:
The Regents of the University of California, Meritage Pharma, Inc.
Inventors:
Ranjan Dohil, John Bastian, Seema Aceves
Abstract: Provided herein are methods for treating gastrointestinal inflammation, for example, esophageal inflammation, or reduction of eosinophilic infiltration of the esophagus and/or reducing local and systemic exposure and/or side effects resulting therefrom. Provided herein are methods for diagnosing gastrointestinal inflammation, for example, esophageal inflammation, or reduction of eosinophilic infiltration of the esophagus.
Abstract: Provided herein are compositions and formulations suitable for the treatment of gastrointestinal disorders. Also provided are methods for treating, preventing, or alleviating disorders of the gastrointestinal tract, for example, those involving the esophagus.
Type:
Application
Filed:
June 11, 2010
Publication date:
April 28, 2011
Applicant:
MERITAGE PHARMA, INC.
Inventors:
Elaine Phillips, Malcolm Hill, Adam Simpson
Abstract: Provided herein are methods for treating the symptoms of and inflammation associated with gastroesophageal reflux disease (GERD) and other conditions. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
Abstract: This document provides methods and compositions suitable for treating eosinophilic esophogitis. For example, this document provides methods that involve administering a steroid and mucoadherent to a mammal (e.g., a human). Kits comprising compositions containing a steroid in combination with a mucoadherent also are provided.
Type:
Application
Filed:
April 20, 2009
Publication date:
October 22, 2009
Applicant:
Meritage Pharma, Inc.
Inventors:
Roger Warndahl, Jeffery Alexander, Gianrico Farrugia
Abstract: Provided herein are methods for preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.