Patents Assigned to Meso Scale Technology
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Patent number: 12013332Abstract: Assay cartridges are described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain embodiments, these cartridges are adapted to receive and analyze a sample collected on an applicator stick. Also described are kits including such cartridges and a cartridge reader configured to analyze an assay conducted using an assay cartridge.Type: GrantFiled: March 30, 2012Date of Patent: June 18, 2024Assignee: Meso Scale Technologies, LLC.Inventors: Nicholas Anderson, Jeffery Debad, Eli N. Glezer, Sudeep Kumar, Noel Lawrence, Kenneth Page, George Sigal, Sharon West
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Publication number: 20240159766Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.Type: ApplicationFiled: December 19, 2023Publication date: May 16, 2024Applicant: Meso Scale Technologies, LLC.Inventors: Charles M. CLINTON, Eli N. GLEZER, Bandele JEFFREY-COKER, Sandor L. KOVACS, Sudeep M. KUMAR, George SIGAL, Carl STEVENS, Michael VOCK
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Patent number: 11982871Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.Type: GrantFiled: October 1, 2021Date of Patent: May 14, 2024Assignee: MESO SCALE TECHNOLOGIES, LLC.Inventors: Ian Chamberlin, Charles M. Clinton, Eli N. Glezer, Bandele Jeffrey-Coker, Manish Kochar, Sandor Kovacs, D. T. Le, Aaron Leimkuehler, George Sigal, Leo Tabakin, Jon Willoughby
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Publication number: 20240151726Abstract: The present invention relates to methods of diagnosing a liver disorder in a patient, as well as methods of monitoring the progression of a liver disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a chemotherapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.Type: ApplicationFiled: January 16, 2024Publication date: May 9, 2024Applicant: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, Anu Mathew, Martin Stengelin, Mingyue Wang
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Patent number: 11971359Abstract: We describe a detection module useful with an apparatus and/or system for conducting luminescence assays, and a kit, a system, an apparatus, and a method incorporating the detection module.Type: GrantFiled: November 16, 2020Date of Patent: April 30, 2024Assignee: Meso Scale Technologies, LLC.Inventors: Charles M. Clinton, Jacob N. Wohlstadter
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Patent number: 11971418Abstract: The present invention relates to methods of diagnosing glomerulonephritis (GN) in a patient, as well as methods of monitoring the progression of GN and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.Type: GrantFiled: February 8, 2021Date of Patent: April 30, 2024Assignee: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, John Kenten, Galina Nikolenko
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Patent number: 11967410Abstract: Methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. Also, algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.Type: GrantFiled: February 22, 2018Date of Patent: April 23, 2024Assignees: Meso Scale Technologies, LLC, THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.Inventors: William F Blakely, Eli N. Glezer, John Kenten, Sudeep Kumar, Anu Mathew, Natalia I. Ossetrova, George Sigal
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Patent number: 11960552Abstract: In examples, a method of controlling customer access to an assay system comprises (a) receiving a system identifier; (b) identifying said system identifier; and (c) utilizing information obtained from the system identifier to perform one or more operations selected from: (i) enabling full access to said system and/or a consumable used in said system; (ii) enabling partial access to said system and/or a consumable used in said system; or (iii) denying access to said system and/or a consumable used in said system.Type: GrantFiled: March 17, 2023Date of Patent: April 16, 2024Assignee: Meso Scale Technologies, LLC.Inventors: Xinri Cong, Jerome Jackson, Carl Stevens, Michael Vock, Jacob N. Wohlstadter
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Patent number: 11951483Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.Type: GrantFiled: March 29, 2021Date of Patent: April 9, 2024Assignee: MESO SCALE TECHNOLOGIES, LLC.Inventors: Eli N. Glezer, Sudeep Kumar, Pankaj Oberoi, George Sigal, Michael Tsionsky
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Patent number: 11940385Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.Type: GrantFiled: February 7, 2019Date of Patent: March 26, 2024Assignee: Meso Scale Technologies, LLC.Inventors: Charles M. Clinton, Eli N. Glezer, Sharon West, George Sigal, Carl Stevens, Michael L. Vock
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Patent number: 11927592Abstract: The present disclosure provides compositions, reagents, kits, systems, system components, and methods for performing assays. More particularly, the disclosure relates to an assay composition for detecting luminescence, which comprises an alkyl diethanolamine, for example, N-butyldiethanolamine (BDEA). In emodiments, the assay composition comprises 2-dibutylaminoethanol (BDAE).Type: GrantFiled: July 20, 2022Date of Patent: March 12, 2024Assignee: MESO SCALE TECHNOLOGIES, LLC.Inventors: Alexander K. Tucker-Schwartz, George Sigal
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Publication number: 20240053364Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.Type: ApplicationFiled: March 27, 2023Publication date: February 15, 2024Applicant: Meso Scale Technologies, LLC.Inventors: Eli N. Glezer, John Kenten, Sudeep Kumar, Galina Nikolenko
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Patent number: 11896979Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. The apparatuses, systems, method, reagents, and kits may be employed in conducting automated analysis in a multi-well plate assay format.Type: GrantFiled: July 15, 2020Date of Patent: February 13, 2024Assignee: MESO SCALE TECHNOLOGIES, LLC.Inventors: Gary I. Krivoy, Cecilia Zimmerman, Jules Vandersarl, Sandor Kovacs, Aaron H. Leimkuehler, Leo Tabakin, Jon Willoughby, Manish Kochar, Charles M. Clinton
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Patent number: 11896978Abstract: Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.Type: GrantFiled: September 25, 2020Date of Patent: February 13, 2024Assignee: MESO SCALE TECHNOLOGIES, LLC.Inventors: Eli N. Glezer, Stephen Higgins, Sandor Kovacs, Sudeep Kumar, Kenneth Page, Kristian Roth, George Sigal
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Publication number: 20240042447Abstract: The invention relates to kits and components thereof used in the conduct of solid-phase binding assays.Type: ApplicationFiled: August 24, 2023Publication date: February 8, 2024Applicant: MESO SCALE TECHNOLOGIES, LLC.Inventors: Yihong Claire Lu, Pankaj Oberoi
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Patent number: 11892455Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.Type: GrantFiled: October 1, 2020Date of Patent: February 6, 2024Assignee: Meso Scale Technologies, LLC.Inventors: Charles M. Clinton, Eli N. Glezer, Bandele Jeffrey-Coker, Sandor L. Kovacs, Sudeep M. Kumar, George Sigal, Carl Stevens, Michael Vock
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Publication number: 20240027456Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.Type: ApplicationFiled: October 4, 2023Publication date: January 25, 2024Applicant: Meso Scale Technologies, LLC.Inventors: Anahit Aghvanyan, Eli N. Glezer, John Kenten, Sudeep Kumar, Galina Nikolenko, Martin Stengelin, Srikant Vaithilingam
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Publication number: 20240027671Abstract: The application is directed to a device housing. The device housing includes a first light device, the first light device including a first electrical supply configured to provide an electrical signal to a first light emitting diode (LED), the first LED separated from a first surface of a diffuser film by a space, wherein the diffuser film includes a second surface, opposite the first surface, the second surface configured to contact a first light pipe.Type: ApplicationFiled: September 20, 2023Publication date: January 25, 2024Applicant: Meso Scale Technologies, LLC.Inventors: Cecilia Zimmerman, Jules VanDersarl
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Patent number: D1016325Type: GrantFiled: August 29, 2023Date of Patent: February 27, 2024Assignee: Meso Scale Technologies, LLC.Inventors: Jacob N. Wohlstadter, Rodger Darin Osborne, Sandor Kovacs, Aaron Leimkuehler, Cecilia Zimmerman, Jules VanDersarl
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Patent number: D1031072Type: GrantFiled: November 2, 2021Date of Patent: June 11, 2024Assignee: Meso Scale Technologies, LLC.Inventors: Eric Jones, Manish Kochar