Patents Assigned to Metabolomycs, Inc.
  • Patent number: 11493516
    Abstract: The present invention relates to a metabolic biomarker set for use in assessing breast cancer in a mammalian subject. In particular, the invention relates to a metabolic biomarker set for screening and/or diagnosing breast cancer, the metabolic biomarker set including at least (a) one amino acid selected from glutamine, glutamate and serine, and one lipid, or (b) glutamine and glutamate. Further, the invention relates to a metabolic biomarker set for prediction of therapeutic response to breast cancer neoadjuvant chemotherapy. Moreover, the present invention relates to a method for assessing breast cancer, which includes obtaining a biological sample, preferably blood, from a mammalian subject and measuring in the biological sample the amount and/or ratios of metabolites. By employing the specific biomarkers and the method according to the present invention it becomes possible to more properly and reliably assess breast cancer.
    Type: Grant
    Filed: March 9, 2021
    Date of Patent: November 8, 2022
    Assignee: Metabolomycs, Inc
    Inventors: Andre Lopes Carvalho, Rene Aloisio Da Costa Vieira, Ismael Dale Cotrim Guerreiro Da Silva, Edson Guimaraes Lo Turco, Therese Koal
  • Publication number: 20220034893
    Abstract: A system and method for using new biomarkers to assess individual diseases is provided. In one embodiment of the present invention, absolute quantification of annotated metabolites by mass spectrometry is used to identify certain biomarkers and derivatives thereof (i.e., signatures), which are then used to screen for, diagnose, predict, prognose, and treat various diseases, including, but not limited to, breast cancer, ovarian cancer, colorectal cancer, pancreatic cancer, and acute graft-versus-host disease.
    Type: Application
    Filed: October 19, 2021
    Publication date: February 3, 2022
    Applicant: Metabolomycs, Inc.
    Inventors: Robert Nagourney, Ismael Silva, Paulo D'Amora
  • Publication number: 20220034892
    Abstract: A system and method for using new biomarkers to assess individual diseases is provided. In one embodiment of the present invention, absolute quantification of annotated metabolites by mass spectrometry is used to identify certain biomarkers and derivatives thereof (i.e., signatures), which are then used to screen for, diagnose, predict, prognose, and treat various diseases, including, but not limited to, breast cancer, ovarian cancer, colorectal cancer, pancreatic cancer, and acute graft-versus-host disease.
    Type: Application
    Filed: October 19, 2021
    Publication date: February 3, 2022
    Applicant: Metabolomycs, Inc.
    Inventors: Robert Nagourney, Ismael Silva, Paulo D'Amora
  • Patent number: 11181524
    Abstract: A system and method for using new biomarkers to assess individual diseases is provided. In one embodiment of the present invention, absolute quantification of annotated metabolites by mass spectrometry is used to identify certain biomarkers and derivatives thereof (i.e., signatures), which are then used to screen for, diagnose, predict, prognose, and treat various diseases, including, but not limited to, breast cancer, ovarian cancer, colorectal cancer, pancreatic cancer, and acute graft-versus-host disease.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: November 23, 2021
    Assignee: Metabolomycs, Inc
    Inventors: Robert Nagourney, Ismael Silva, Paulo D'Amora
  • Publication number: 20210003578
    Abstract: A system and method for using new biomarkers to assess individual diseases is provided. In one embodiment of the present invention, absolute quantification of annotated metabolites by mass spectrometry is used to identify certain biomarkers and derivatives thereof (i.e., signatures), which are then used to screen for, diagnose, predict, prognose, and treat various diseases, including, but not limited to, breast cancer, ovarian cancer, colorectal cancer, pancreatic cancer, and acute graft-versus-host disease.
    Type: Application
    Filed: March 8, 2020
    Publication date: January 7, 2021
    Applicant: Metabolomycs, Inc.
    Inventors: Robert Nagourney, Ismael Silva, Paulo D'Amora
  • Publication number: 20200386766
    Abstract: A system and method for using new biomarkers to assess individual diseases, including, but not limited to, a patient's prognosis before and/or after being diagnosed with the disease. In one embodiment of the present invention, absolute quantification of annotated metabolites by mass spectrometry is used to identify certain biomarkers and derivatives thereof (i.e., signatures), which are then used to screen for, diagnose, predict, prognose, and/or treat various diseases, including, but not limited to, COVID-19.
    Type: Application
    Filed: July 6, 2020
    Publication date: December 10, 2020
    Applicant: Metabolomycs, Inc.
    Inventors: Robert Nagourney, Ismael Silva, Paulo D'Amora
  • Publication number: 20200200754
    Abstract: A system and method for using new biomarkers to assess individual diseases is provided. In one embodiment of the present invention, absolute quantification of annotated metabolites by mass spectrometry is used to identify certain biomarkers and derivatives thereof (i.e., signatures), which are then used to screen for, diagnose, predict, prognose, and treat various diseases, including, but not limited to, breast cancer, ovarian cancer, colorectal cancer, pancreatic cancer, and acute graft-versus-host disease.
    Type: Application
    Filed: December 16, 2019
    Publication date: June 25, 2020
    Applicant: Metabolomycs, Inc.
    Inventors: Robert Nagourney, Ismael Silva, Paulo D'Amora
  • Publication number: 20190383819
    Abstract: A system and method for using new biomarkers to assess individual diseases is provided. In one embodiment of the present invention, absolute quantification of annotated metabolites by mass spectrometry is used to identify certain biomarkers and derivatives thereof (i.e., signatures), which are then used to screen for, diagnose, predict, prognose, and treat various diseases, including, but not limited to, breast cancer, ovarian cancer, colorectal cancer, pancreatic cancer, and acute graft-versus-host disease.
    Type: Application
    Filed: June 14, 2019
    Publication date: December 19, 2019
    Applicant: Metabolomycs, Inc.
    Inventors: Robert Nagourney, Ismael Silva, Paulo D'Amora