Abstract: An analyte sensor and systems for determining analyte levels in a user's body. The analyte sensor and systems are adapted to be used with single dose medication devices and include a communication system to transmit the communications from the analyte sensor to the user to notify the user of an estimated amount of fluid to deliver to the user's body. More particularly, these apparatuses and methods for use are for providing convenient monitoring of blood glucose levels in determining the appropriate amount of insulin to deliver.
Type:
Application
Filed:
December 6, 2006
Publication date:
June 12, 2008
Applicant:
METRONIC MINIMED, INC.
Inventors:
John J. Mastrototaro, Rajiv Shah, Partha Ray, Kenny J. Long, Andrew C. Hayes, Nandita Patel, Cary D. Talbot, Bahar Reghabi
Abstract: A system is provided for monitoring blood glucose data of a patient. The system includes a sensing device and hospital monitor. The sensing device includes a sensor and sensor electronics and is adapted to transmit information to the hospital monitor while continuing to sense blood glucose data. The communication between the sensing device and the hospital monitor may be wireless. The sensor electronics may include a sensor power supply, a voltage regulator, and optionally a memory and processor.
Type:
Application
Filed:
December 4, 2006
Publication date:
May 3, 2007
Applicant:
METRONIC MINIMED, INC.
Inventors:
John Mastrototaro, Rajiv Shah, Partha Ray, Kenny Long, Andrew Hayes, Nandita Patel, Cary Talbot, Bahar Reghabi
Abstract: Embodiments of the invention are directed to a method of estimating the physical stability of a protein formulation. A particular embodiment of the invention places the protein formulation under an agitational stress that causes the protein to aggregate at an accelerated rate. In one embodiment, the change in protein aggregation is monitored spectroscopically using Thioflavin-T. Embodiments of the invention then utilize a survival curve analysis to ascertain the relative physical stability of the different protein formulations under study. This method was used to develop novel surfactant-stabilized insulin formulations in a rapid, cost efficient manner, thus illustrating the utility of the inventive method to the discovery and development of pharmaceutical protein formulations.
Type:
Grant
Filed:
October 18, 2001
Date of Patent:
May 18, 2004
Assignee:
Metronic MiniMed, Inc.
Inventors:
Seonyoung Kim, William P. Van Antwerp, Todd M. Gross, Poonam S. Gulati